Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Younhee Ko"'
Autor:
Daehong Kwon, Jiyeong Ahn, Hyeonji Kim, Heesun Kim, Junyoung Kim, Suyeon Wy, Younhee Ko, Jaebum Kim
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Currently, diverse minipigs have acquired a common dwarfism phenotype through independent artificial selections. Characterizing the population and genetic diversity in minipigs is important to unveil genetic mechanisms regulating
Externí odkaz:
https://doaj.org/article/2f49b550a9cc4f798eff0441096cd44e
Autor:
Jaehwan Kim, Jongmi Lee, Xuan Li, Norma Kunjravia, Darshna Rambhia, Inna Cueto, Katherine Kim, Vasuma Chaparala, Younhee Ko, Sandra Garcet, Wei Zhou, Junyue Cao, James G. Krueger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Durable psoriasis improvement has been reported in a subset of psoriasis patients after treatment withdrawal of biologics blocking IL-23/Type 17 T-cell (T17) autoimmune axis. However, it is not well understood if systemic blockade of the IL-23/T17 ax
Externí odkaz:
https://doaj.org/article/c88bd241872747988a0bece722d3d3d0
Autor:
Mikang Sim, Jongin Lee, Daehong Kwon, Daehwan Lee, Nayoung Park, Suyeon Wy, Younhee Ko, Jaebum Kim
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 444-451 (2023)
Constructing accurate microbial genome assemblies is necessary to understand genetic diversity in microbial genomes and its functional consequences. However, it still remains as a challenging task especially when only short-read sequencing technologi
Externí odkaz:
https://doaj.org/article/1510106d81d24290bcfee5ca828b533f
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2469 (2023)
Drug–drug interactions (DDI) occur because of the unexpected pharmacological effects of drug pairs. Although drug efficacy can be improved by taking two or more drugs in the short term, this may cause inevitable side effects. Currently, multiple dr
Externí odkaz:
https://doaj.org/article/a303b295a73943f8ab0f2f1461fc3949
Autor:
Seoung Wan Nam, Kwang Seob Lee, Jae Won Yang, Younhee Ko, Michael Eisenhut, Keum Hwa Lee, Jae Il Shin, Andreas Kronbichler
Publikováno v:
Clinical and Experimental Pediatrics, Vol 64, Iss 5, Pp 208-222 (2021)
The publication of genetic epidemiology meta-analyses has increased rapidly, but it has been suggested that many of the statistically significant results are false positive. In addition, most such meta-analyses have been redundant, duplicate, and err
Externí odkaz:
https://doaj.org/article/e86b4a14e68d429da9bc3f48403d866d
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253190 (2021)
Crop tolerance to crowding stress, specifically plant population density, is an important target to improve productivity in processing sweet corn. Due to limited knowledge of biological mechanisms involved in crowding stress in sweet corn, a study wa
Externí odkaz:
https://doaj.org/article/e9247415986f4fd2b5da2779848a09dd
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background Advances in sequencing technologies have facilitated large-scale comparative genomics based on whole genome sequencing. Constructing and investigating conserved genomic regions among multiple species (called synteny blocks) are es
Externí odkaz:
https://doaj.org/article/b41708c34548489d9ab9c027906853c5
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-14 (2018)
Stroke: creating a safe haven for neurological repair A potent “survival signal” for brain stem cells could enable effective regenerative therapies for stroke patients. Neural progenitor cells (NPCs) can develop into functional neurons and suppor
Externí odkaz:
https://doaj.org/article/b185d6e8def74fbf8a8603d23fb4d92a
Autor:
Jinhee Lee, Min Ji Son, Chei Yun Son, Gwang Hun Jeong, Keum Hwa Lee, Kwang Seob Lee, Younhee Ko, Jong Yeob Kim, Jun Young Lee, Joaquim Radua, Michael Eisenhut, Florence Gressier, Ai Koyanagi, Brendon Stubbs, Marco Solmi, Theodor B. Rais, Andreas Kronbichler, Elena Dragioti, Daniel Fernando Pereira Vasconcelos, Felipe Rodolfo Pereira da Silva, Kalthoum Tizaoui, André Russowsky Brunoni, Andre F. Carvalho, Sarah Cargnin, Salvatore Terrazzino, Andrew Stickley, Lee Smith, Trevor Thompson, Jae Il Shin, Paolo Fusar-Poli
Publikováno v:
Brain Sciences, Vol 10, Iss 10, p 692 (2020)
This study aimed to verify noteworthy findings between genetic risk factors and autism spectrum disorder (ASD) by employing the false positive report probability (FPRP) and the Bayesian false-discovery probability (BFDP). PubMed and the Genome-Wide A
Externí odkaz:
https://doaj.org/article/bc5b13cc1a8941d9bebcd3e2e34557a8
Autor:
Younhee Ko
Publikováno v:
Applied Sciences, Vol 10, Iss 15, p 5076 (2020)
Novel drug discovery is time-consuming, costly, and a high-investment process due to the high attrition rate. Therefore, many trials are conducted to reuse existing drugs to treat pressing conditions and diseases, since their safety profiles and phar
Externí odkaz:
https://doaj.org/article/4e3068c15d944540b01e692009b0e3e8