Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Youngsu C, Kwon"'
Autor:
Hans D. Brightbill, Eric Suto, Nicole Blaquiere, Nandhini Ramamoorthi, Swathi Sujatha-Bhaskar, Emily B. Gogol, Georgette M. Castanedo, Benjamin T. Jackson, Youngsu C. Kwon, Susan Haller, Justin Lesch, Karin Bents, Christine Everett, Pawan Bir Kohli, Sandra Linge, Laura Christian, Kathy Barrett, Allan Jaochico, Leonid M. Berezhkovskiy, Peter W. Fan, Zora Modrusan, Kelli Veliz, Michael J. Townsend, Jason DeVoss, Adam R. Johnson, Robert Godemann, Wyne P. Lee, Cary D. Austin, Brent S. McKenzie, Jason A. Hackney, James J. Crawford, Steven T. Staben, Moulay H. Alaoui Ismaili, Lawren C. Wu, Nico Ghilardi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Clinical trials of BAFF blockade with belimumab have shown partial efficacy for the treatment of systemic lupus erythematosus (SLE), so other therapeutic options are required. Here, the authors present a new small molecule inhibitor that targets NIK
Externí odkaz:
https://doaj.org/article/c1b21708fc0a4c58b4c58242d9d32c50
Autor:
Jieqiong Zhang, Joshua D. Webster, Debra L. Dugger, Tatiana Goncharov, Merone Roose-Girma, Jeffrey Hung, Youngsu C. Kwon, Domagoj Vucic, Kim Newton, Vishva M. Dixit
Publikováno v:
Cell Reports, Vol 27, Iss 9, Pp 2679-2689.e3 (2019)
Summary: Cellular inhibitor of apoptosis proteins cIAP1 and cIAP2 ubiquitinate nuclear factor κB (NF-κB)-inducing kinase (NIK) to suppress non-canonical NF-κB signaling and substrates such as receptor interacting protein kinase 1 (RIPK1) to promot
Externí odkaz:
https://doaj.org/article/8a63ee8ba40f4915a2963d7757c79bef
Autor:
Alexander D, Gitlin, Klaus, Heger, Alexander F, Schubert, Rohit, Reja, Donghong, Yan, Victoria C, Pham, Eric, Suto, Juan, Zhang, Youngsu C, Kwon, Emily C, Freund, Jing, Kang, Anna, Pham, Roger, Caothien, Natasha, Bacarro, Trent, Hinkle, Min, Xu, Brent S, McKenzie, Benjamin, Haley, Wyne P, Lee, Jennie R, Lill, Merone, Roose-Girma, Monika, Dohse, Joshua D, Webster, Kim, Newton, Vishva M, Dixit
Publikováno v:
Nature. 587(7833)
Mutations in the death receptor FAS