Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Youngsok, Choi"'
Autor:
HeeJi Lee, Dong Wook Han, Hyeonwoo La, Chanhyeok Park, Kiye Kang, Ohbeom Kwon, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Publikováno v:
Animal Bioscience, Vol 37, Iss 9, Pp 1635-1643 (2024)
Objective Disruptor of telomeric silencing 1-like (DOT1L) is the only known histone H3K79 methyltransferase essential for the development of the embryonic cardiovascular system, including the heart, blood vessels, and lymphatic vessels, through trans
Externí odkaz:
https://doaj.org/article/b27f067bf8364bfc8bea1b13712ffa32
Autor:
Hyeonji Lee, Dong Wook Han, Seonho Yoo, Ohbeom Kwon, Hyeonwoo La, Chanhyeok Park, Heeji Lee, Kiye Kang, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Publikováno v:
Animal Bioscience, Vol 37, Iss 6, Pp 1021-1030 (2024)
Objective R-loops are DNA:RNA triplex hybrids, and their metabolism is tightly regulated by transcriptional regulation, DNA damage response, and chromatin structure dynamics. R-loop homeostasis is dynamically regulated and closely associated with gen
Externí odkaz:
https://doaj.org/article/16c49cd087aa4c91b5bdc0e4cb3fd2bb
Autor:
Seung Chel Yang, Mira Park, Kwon-Ho Hong, Hyeonwoo La, Chanhyeok Park, Peike Wang, Gaizhen Li, Qionghua Chen, Youngsok Choi, Francesco J. DeMayo, John P. Lydon, David G. Skalnik, Hyunjung J. Lim, Seok-Ho Hong, So Hee Park, Yeon Sun Kim, Hye-Ryun Kim, Haengseok Song
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Progesterone (P4) is required for the preparation of the endometrium for a successful pregnancy. P4 resistance is a leading cause of the pathogenesis of endometrial disorders like endometriosis, often leading to infertility; however, the und
Externí odkaz:
https://doaj.org/article/6444b23feea846438ea6b8cd5143100b
Autor:
Nguyen Xuan Thang, Dong Wook Han, Chanhyeok Park, Hyeonji Lee, Hyeonwoo La, Seonho Yoo, Heeji Lee, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Kyoung Sik Park, Youngsok Choi, Kwonho Hong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The aberrant function of ATP-dependent chromatin remodeler INO80 has been implicated in multiple types of cancers by altering chromatin architecture and gene expression; however, the underlying mechanism of the functional involvement of INO80 mutatio
Externí odkaz:
https://doaj.org/article/4e3831288ec0422f85f4d7a4a9c0e81a
Autor:
Byeongseok Kim, Ki Hoon Park, Ok-Hee Lee, Giwan Lee, Hyukjung Kim, Siyoung Lee, Semi Hwang, Young Bong Kim, Youngsok Choi
Publikováno v:
Animal Bioscience, Vol 36, Iss 1, Pp 43-52 (2023)
Objective This study aimed to examine the influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on pregnancy in cytokeratin-18 (K18)-hACE2 transgenic mice. Methods To determine the expression of hACE2 mRNA in the female
Externí odkaz:
https://doaj.org/article/3fd6014d34744308876b161c212ea3ce
Publikováno v:
Journal of Animal Reproduction and Biotechnology, Vol 37, Iss 3, Pp 183-192 (2022)
Lipopolysaccharide (LPS) is an endotoxin factor present in the cell wall of Gram-negative bacteria and induces various immune responses to infection. Recent studies have reported that LPS induces cellular stress in various cells including oocytes and
Externí odkaz:
https://doaj.org/article/6584e186bc28491ba0ad481d1e6c415b
Autor:
Hyunjin Yoo, Hyeonwoo La, Chanhyeok Park, Seonho Yoo, Hyeonji Lee, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Epigenetic mechanisms are mandatory for endothelial called lymphangioblasts during cardiovascular development. Dot1l-mediated gene transcription in mice is essential for the development and function of lymphatic ECs (LECs). The role of Dot1l in the d
Externí odkaz:
https://doaj.org/article/f3098734b54144e0916b76357dc31c76
Publikováno v:
Animal Bioscience, Vol 34, Iss 4, Pp 533-538 (2021)
Objective Pluripotent stem cell-derived lymphatic endothelial cells (LECs) show great promise in their therapeutic application in the field of regenerative medicine related to lymphatic vessels. We tested the approach of forced differentiation of mou
Externí odkaz:
https://doaj.org/article/7446010ec5f248d9b1b898fdca9a3d16
Autor:
Ok-Hee Lee, Siyoung Lee, Miseon Park, Sohyeon Moon, Semi Hwang, Byeongseok Kim, C-Yoon Kim, Dong Ryul Lee, Sung Han Shim, Keun-Hong Park, Hyung Min Chung, Youngsok Choi
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102643- (2022)
Beta2-microglobulin (B2M) is a subunit of human leukocyte antigen class-I (HLA-I) heterodimer that mediates immune rejection through activation of cytotoxic T cells. B2M binding to HLA-I proteins is essential for functional HLA-I on the cell surface.
Externí odkaz:
https://doaj.org/article/4e9016da851f4729a2aed98e77593fcc
Publikováno v:
Theriogenology. 202:125-135