Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Youngju Shim"'
Publikováno v:
Journal of the Korean Society for Aeronautical & Space Sciences. 51:199-205
Autor:
Massimo Loda, Sabina Signoretti, Fionnuala O'Connell, Lily Pao, Ji Luo, Benjamin G. Neel, Ronald A. DePinho, John M. Watt, Youngju Shim, Eyoung Shin, Lewis C. Cantley, Nicole M. Logsdon, Cassandra L. Sobkiw
Publikováno v:
Proceedings of the National Academy of Sciences. 102:10238-10243
Mice with heterozygous deletion of the PTEN tumor suppressor gene develop a range of epithelial neoplasia as well as lymphoid hyperplasia. Previous studies suggest that PTEN suppresses tumor formation by acting as a phosphoinositide phosphatase to li