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pro vyhledávání: '"Youngjik Choi"'
Autor:
Zoya Leonenko, Simon J. Attwood, Mikko Karttunen, Elizabeth Drolle, Youngjik Choi, Matthew I. Hoopes
Publikováno v:
Soft Matter. 10:206-213
Melatonin is a pineal hormone that has been shown to have protective effects in several diseases that are associated with cholesterol dysregulation, including cardiovascular disease, Alzheimer's disease, and certain types of cancers. Cholesterol is a
Autor:
Elizabeth Drolle, Mikko Karttunen, Matthew I. Hoopes, Youngjik Choi, Norbert Kučerka, Zoya Leonenko, John Katsaras
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828:2247-2254
article i nfo The cell membrane plays an important role in the molecular mechanism of amyloid toxicity associated with Alzheimer's disease. The membrane's chemical composition and the incorporation of small molecules, such as melatonin and cholestero
Publikováno v:
International Journal of Molecular Sciences; Volume 14; Issue 2; Pages: 3514-3539
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 3514-3539 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 3514-3539 (2013)
Cell membranes are typically very complex, consisting of a multitude of different lipids and proteins. Supported lipid bilayers are widely used as model systems to study biological membranes. Atomic force microscopy and force spectroscopy techniques
Publikováno v:
Biophysical Journal. 104(2)
The cell membrane plays an important role in amyloid toxicity in relation to Alzheimer's disease. The membrane's composition and the inclusion of small molecules, such as melatonin and cholesterol, may alter the membrane's structure and physical prop
Autor:
Simon J. Attwood, Zoya Leonenko, Ravi Gaikwad, Elizabeth Drolle, Francis T. Hane, Youngjik Choi
Publikováno v:
Microscopy and Microanalysis. 18:884-885
Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 – August 2, 2012.
Publikováno v:
Biophysical Journal. (3):86a
Alzheimer's disease is a progressive neurodegenerative disease associated with amyloid fibril formation in the brain. The exact molecular mechanism of amyloid fibril formation and toxicity is not well understood, which delays development of novel and