Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Youngjae You"'
Autor:
Pritam Thapa, Mengjie Li, Radha Karki, Moses Bio, Pallavi Rajaputra, Gregory Nkepang, Sukyung Woo, Youngjae You
Publikováno v:
ACS Omega, Vol 2, Iss 10, Pp 6349-6360 (2017)
Externí odkaz:
https://doaj.org/article/d1cb7868843a4d84b97a43b8663cefc0
Publikováno v:
Photochemistry and Photobiology. 99:420-436
Bladder cancer is the first cancer for which PDT was clinically approved in 1993. Unfortunately, it was unsuccessful due to side effects like bladder contraction. Here, we summarized the recent progress of PDT for bladder cancers, focusing on photose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f95fbeadb63d6cc4ad61d6313f89de7
https://doi.org/10.1111/php.13726
https://doi.org/10.1111/php.13726
Autor:
Luong Nguyen, Daniel C. Schultz, Simon S. Terzyan, Mohammad Rezaei, Jinhua Songb, Chenglong Li, Youngjae You, Marie H. Hanigan
Publikováno v:
Bioorganicmedicinal chemistry. 73
Inhibitors of gamma-glutamyl transpeptidase (GGT1, aka gamma-glutamyl transferase) are needed for the treatment of cancer, cardiovascular illness and other diseases. Compounds that inhibit GGT1 have been evaluated in the clinic, but no inhibitor has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c6b4be1bea147cd53c17e8e1104980
https://pubmed.ncbi.nlm.nih.gov/36208545
https://pubmed.ncbi.nlm.nih.gov/36208545
Autor:
Martin J. Schnermann, Youngjae You
Publikováno v:
Photochemistry and photobiology. 98(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5034a8f6c43b003006538f4fe74966e0
https://pubmed.ncbi.nlm.nih.gov/35297552
https://pubmed.ncbi.nlm.nih.gov/35297552
Publikováno v:
Photochemistry and photobiologyREFERENCES. 98(2)
We established a light-activatable prodrug strategy that produces the combination effect of photodynamic therapy (PDT) and site-specific chemotherapy. Prodrugs are activated by singlet oxygen (SO), generated from PS and visible or near IR light, in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce7cf9e7a46f2f27323253acf82d8cb
https://pubmed.ncbi.nlm.nih.gov/34970997
https://pubmed.ncbi.nlm.nih.gov/34970997
Publikováno v:
Journal of Clinical Medicine
Photodynamic therapy (PDT) has become an effective treatment for certain types of solid tumors. The combination of PDT with other therapies has been extensively investigated in recent years to improve its effectiveness and expand its applications. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33230226882cd04d795d05ecd0a2697c
http://europepmc.org/articles/PMC6947033
http://europepmc.org/articles/PMC6947033
Autor:
Pallavi Rajaputra, Cody J. Peer, Pritam Thapa, Youngjae You, Sukyung Woo, William D. Figg, Mengjie Li, Moses Bio
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 44:521-536
The combination of photodynamic therapy (PDT) with anti-tumor agents is a complimentary strategy to treat local cancers. We developed a unique photosensitizer (PS)-conjugated paclitaxel (PTX) prodrug in which a PS is excited by near-infrared waveleng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dadfd90cfdcc3bd0d8675b206c551c
https://doi.org/10.1007/s10928-017-9543-z
https://doi.org/10.1007/s10928-017-9543-z
Autor:
Jin-Young Yang, Youngjae You
Publikováno v:
Journal of Dental Hygiene Science. 16:401-408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cf098fb9f2d7c10d08da045abb87c15
https://doi.org/10.17135/jdhs.2016.16.6.401
https://doi.org/10.17135/jdhs.2016.16.6.401
Autor:
Jessica Kindrick, Cody J. Peer, Bharathiraja Subramaniyan, Moses Bio, Sukyung Woo, Mengjie Li, Luong T. Nguyen, Youngjae You, William D. Figg
Publikováno v:
J Control Release
Photodynamic therapy (PDT) is a clinically approved therapeutic modality to treat certain types of cancers. However, incomplete ablation of tumor is a challenge. Visible and near IR-activatable prodrug, exhibiting the combined effects of PDT and loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ae2291e55ee67457c28f17208bb414
https://pubmed.ncbi.nlm.nih.gov/31299262
https://pubmed.ncbi.nlm.nih.gov/31299262
Autor:
Moses Bio, Kazi Md Mahabubur Rahman, Youngjae You, Robert E. Hurst, Pallavi Rajaputra, Irene Lim
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(12)
Systemic side effects and high hydrophobicity are major disadvantages of paclitaxel (PTX), one of the most popular anticancer drugs. Here, we present singlet oxygen (SO)-activatable and mitochondria-targeted PTX prodrugs to overcome these problems an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31607aebb75603cff98b9266f0fa2629
https://pubmed.ncbi.nlm.nih.gov/30987891
https://pubmed.ncbi.nlm.nih.gov/30987891