Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Younghyoun Yoon"'
Autor:
Hui-Kuo G Shu, Younghyoun Yoon, Samuel Hong, Kaiming Xu, Huiying Gao, Chunhai Hao, Edilson Torres-Gonzalez, Cardenes Nayra, Mauricio Rojas, Hyunsuk Shim
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79768 (2013)
A devastating late injury caused by radiation is pulmonary fibrosis. This risk may limit the volume of irradiation and compromise potentially curative therapy. Therefore, development of a therapy to prevent this toxicity can be of great benefit for t
Externí odkaz:
https://doaj.org/article/8b213b1cfa984cf09ef8f3e25e3e3494
Autor:
Zhongxing Liang, Weiqiang Zhan, Aizhi Zhu, Younghyoun Yoon, Songbai Lin, Maiko Sasaki, Jan-Michael A Klapproth, Hua Yang, Hans E Grossniklaus, Jianguo Xu, Mauricio Rojas, Ronald J Voll, Mark M Goodman, Richard F Arrendale, Jin Liu, C Chris Yun, James P Snyder, Dennis C Liotta, Hyunsuk Shim
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34038 (2012)
Metastasis, the spread and growth of tumor cells to distant organ sites, represents the most devastating attribute and plays a major role in the morbidity and mortality of cancer. Inflammation is crucial for malignant tumor transformation and surviva
Externí odkaz:
https://doaj.org/article/56ba1df1025349fea67ceff4c086a48d
Autor:
Hyunsuk Shim, Zhuo (Georgia) Chen, Mark M. Goodman, Dong M. Shin, Heidi T. Cho, Aizhi Zhu, Mison Choe, Xin Zhang, Zhongxing Liang, Younghyoun Yoon
Squamous cell carcinoma of the head and neck (SCCHN) metastasizes to the lymph nodes and lungs. We have generated previously an orthotopic mouse model for head and neck metastasis and did in vivo selection of SCCHN cells through four rounds of serial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d9de019ece513cbe6960e4534a2542
https://doi.org/10.1158/0008-5472.c.6494897
https://doi.org/10.1158/0008-5472.c.6494897
Autor:
Hyunsuk Shim, Zhuo (Georgia) Chen, Mark M. Goodman, Dong M. Shin, Heidi T. Cho, Aizhi Zhu, Mison Choe, Xin Zhang, Zhongxing Liang, Younghyoun Yoon
Supplementary Figures 1-4 from CXC Chemokine Receptor-4 Antagonist Blocks Both Growth of Primary Tumor and Metastasis of Head and Neck Cancer in Xenograft Mouse Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542bacb837b8f460ab1b05d4864cf395
https://doi.org/10.1158/0008-5472.22365869
https://doi.org/10.1158/0008-5472.22365869
Autor:
Karthik Ramesh, Zhongxing Liang, J. Scott Cordova, Saumya S. Gurbani, Robert H. Press, Brent D. Weinberg, José E. Velázquez Vega, Eric Salgado, Eduard Schreibmann, Jeffrey J. Olson, Hui-Kuo Shu, Alfredo Voloschin, Younghyoun Yoon, Hyunsuk Shim
Publikováno v:
Tomography
Tomography; Volume 5; Issue 1; Pages: 53-60
Volume 5
Issue 1
Pages 53-60
Tomography; Volume 5; Issue 1; Pages: 53-60
Volume 5
Issue 1
Pages 53-60
Histone deacetylases regulate a wide variety of cellular functions and have been implicated in redifferentiation of various tumors. Histone deacetylase inhibitors (HDACi) are potential pharmacologic agents to improve outcomes for patients with glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86200f57f48444ae85c85129e577ff92
https://doi.org/10.18383/j.tom.2018.00031
https://doi.org/10.18383/j.tom.2018.00031
Publikováno v:
Advanced Therapeutics. 5:2100223
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc0c905cf110cb503e0b02b839a2f04a
https://doi.org/10.1002/adtp.202100223
https://doi.org/10.1002/adtp.202100223
Autor:
Zhongxing Liang, Saumya S. Gurbani, Younghyoun Yoon, Eric Salgado, Amber Feng, Hyunsuk Shim, Renren Bai
Publikováno v:
European Journal of Medicinal Chemistry. 136:360-371
CXCR4 plays a crucial role in the inflammatory disease process, providing an attractive means for drug targeting. A series of novel amide-sulfamide derivatives were designed, synthesized and comprehensively evaluated. This new scaffold exhibited much
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb96086047ac5bcb5a1dc8e4ceb2b4c
https://doi.org/10.1016/j.ejmech.2017.05.030
https://doi.org/10.1016/j.ejmech.2017.05.030
Autor:
Zhongxing Liang, Yoon Hyeun Oum, Hyunsuk Shim, Ronald J. Voll, Dinesh K. Shetty, Younghyoun Yoon, Mark M. Goodman
Publikováno v:
Bioorg Med Chem
CXCR4 is involved in various diseases such as inflammation, tumor growth, and cancer metastasis through the interaction with its natural endogenous ligand, chemokine CXCL12. In an effort to develop imaging probes for CXCR4, we developed a novel small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df44204c856a9ca00b87607551264831
https://europepmc.org/articles/PMC6942325/
https://europepmc.org/articles/PMC6942325/
Autor:
Hyunsuk Shim, Wenyan Yu, Renren Bai, Zhongxing Liang, Yuanyuan Xie, Rui Wu, Younghyoun Yoon, Chuansheng Yao
Publikováno v:
European journal of medicinal chemistry. 185
Breast cancer is the most frequently diagnosed malignancy and the second common cause of death in women worldwide. High mortality in breast cancer is frequently associated with metastatic progression rather than the primary tumor itself. It has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bec9dedd809c7a3b5655243c4eedf42
https://pubmed.ncbi.nlm.nih.gov/31698158
https://pubmed.ncbi.nlm.nih.gov/31698158
Autor:
Zhongxing Liang, Francisco Javier Garcia, Younghyoun Yoon, Theresa Gaines, Saniya Virani, Hyunsuk Shim, Yoon Hyeun Oum, Suazette Reid Mooring
Publikováno v:
European journal of medicinal chemistry. 181
The interaction between G-Protein coupled receptor CXCR4 and its natural ligand CXCL12 has been linked to inflammation experienced by patients with Irritable Bowel Disease (IBD). Blocking this interaction could potentially reduce inflammatory symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416b6253b03f2785fa28960ea2fa0626
https://pubmed.ncbi.nlm.nih.gov/31377592
https://pubmed.ncbi.nlm.nih.gov/31377592