Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Younger W"'
Autor:
Chung-Feng Kao, Po-Hsiu Kuo, Younger W.-Y. Yu, Albert C. Yang, Eugene Lin, Yu-Li Liu, Shih-Jen Tsai
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The serotonin [5-hydroxytryptamine (5-HT)] system has been implicated in the pathogenesis of major depressive disorder (MDD). Among the 5-HT receptor subtypes, 5-HT2 is one of the major pharmacological therapeutic targets for MDD. There have been inc
Externí odkaz:
https://doaj.org/article/5189aa30120543c6802f25bb5da36a4b
Autor:
Chung-Feng Kao, Yu-Li Liu, Younger W.-Y. Yu, Albert C. Yang, Eugene Lin, Po-Hsiu Kuo, Shih-Jen Tsai
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract It is well established that brain-derived neurotrophic factor (BDNF) signaling pathway plays a key role in the pathophysiology of major depressive disorder (MDD) and in therapeutic mechanisms of antidepressants. We aim to identify genetic va
Externí odkaz:
https://doaj.org/article/99bed60d7b9f4c5dbed09c6b9762adde
Publikováno v:
Pharmaceuticals, Vol 13, Iss 10, p 305 (2020)
In the wake of recent advances in machine learning research, the study of pharmacogenomics using predictive algorithms serves as a new paradigmatic application. In this work, our goal was to explore an ensemble machine learning approach which aims to
Externí odkaz:
https://doaj.org/article/56f72dcf98744112bf8c61bac5daefef
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
In the wake of recent advances in scientific research, personalized medicine using deep learning techniques represents a new paradigm. In this work, our goal was to establish deep learning models which distinguish responders from non-responders, and
Externí odkaz:
https://doaj.org/article/2e0ecc36c1c442a59abfb7d5f960fa8a
Autor:
Ying-Jay Liou, Chien-Hsiun Chen, Chih-Ya Cheng, Shiow-Yi Chen, Tai-Jui Chen, Younger W-Y Yu, Fang-Shin Nian, Shih-Jen Tsai, Chen-Jee Hong
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e32984 (2012)
OBJECTIVES: The forced swim test (FST) is a commonly used model to predict antidepressant efficacy. Uncovering the genetic basis of the model may unravel the mechanism of antidepressant treatment. METHODS: FVB/NJ (FVB) and C57BL/6J (B6) were first id
Externí odkaz:
https://doaj.org/article/7a48a5fcc4064ba9875b8dee4e19ffc9
Autor:
Adebileje, Sikiru A., Alexander, Steven D., Amma, Maya R., Anjomrouz, Marzieh, Asghariomabad, Fatemeh, Atharifard, Ali, Atlas, James, Bell, Stephen T., Butler, Anthony P.H., Butler, Philip H., Carbonez, Pierre, Chambers, Claire, Chapagain, Krishna M., Chernoglazov, Alexander I., Clark, Jennifer A., Colgan, Frances, Crighton, Jonathan S., Dahal, Shishir, Damet, Jérôme, Dapamede, Theodorus, de Ruiter, Niels J.A., Dixit, Devyani, Doesburg, Robert M.N., Dombroski, Karen, Duncan, Neryda, Gieseg, Steven P., Gopinathan, Anish, Healy, Joseph L., Holmes, Luke, Jonker, Kevin, Kirkbride, Tracy, Lowe, Chiara, Mandalika, V.B.H., Matanaghi, Aysouda, Moghiseh, Mahdieh, Paladugu, Manoj, Palmer, David, Panta, Raj K., Renaud, Peter, Sayous, Yann, Schleich, Nanette, Searle, Emily, Sheeja, Jereena S., Smith, Aaron, Broeke, Leza Vanden, Vivek, V.S., Peter Walker, E., Wijesooriya, Manoj, Ross Younger, W., Healy, Joe, Panta, Raj Kumar, Chernoglazov, Alex, Roake, Justin, Butler, Phil, Butler, Anthony
Publikováno v:
In Atherosclerosis August 2023 378
Autor:
Younger W-Y. Yu, 余伍洋
89
Telomere, the ends of chromosomes, consists of simple hexameric repeats. In human, TTAGGG repeat is found at the ends of all chromosomes. Telomeres progressively shorten with age in somatic cells, because the insufficient telomerase activity
Telomere, the ends of chromosomes, consists of simple hexameric repeats. In human, TTAGGG repeat is found at the ends of all chromosomes. Telomeres progressively shorten with age in somatic cells, because the insufficient telomerase activity
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/64084735775007799150
Publikováno v:
In Intelligence January-February 2012 40(1):38-48
Publikováno v:
In Psychiatry Research: Neuroimaging 30 December 2011 194(3):372-377
Publikováno v:
In Journal of Affective Disorders June 2011 131(1-3):243-250