Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Young-Un Park"'
Autor:
Su Been Lee, Jihyun Park, Yongdo Kwak, Young-Un Park, Truong Thi My Nhung, Bo Kyoung Suh, Youngsik Woo, Yeongjun Suh, Eunbyul Cho, Sehyung Cho, Sang Ki Park
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Disrupted-in-schizophrenia 1 (DISC1) is a scaffold protein that has been implicated in multiple mental disorders. DISC1 is known to regulate neuronal proliferation, signaling, and intracellular calcium homeostasis, as well as neurodevelopmen
Externí odkaz:
https://doaj.org/article/a569f15b88964372a19681cbdbc3d327
Autor:
Saebom Lee, Jaehoon Jeong, Young-Un Park, Yongdo Kwak, Seol Ae Lee, Haeryun Lee, Hyeon Son, Sang Ki Park
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/190432a5736a4607a9020c7699bbce42
Autor:
Jaehoon Jeong, Young-Un Park, Dae-Kyum Kim, Saebom Lee, Yongdo Kwak, Seol-Ae Lee, Haeryun Lee, Yoo-Hun Suh, Yong Song Gho, Daehee Hwang, Sang Ki Park
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84482 (2013)
The dopamine D2 receptor (DRD2) is a key receptor that mediates dopamine-associated brain functions such as mood, reward, and emotion. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase whose function has been implicated i
Externí odkaz:
https://doaj.org/article/db3bdd0e6d684b54a8daae3a16bfd53a
Autor:
Saebom Lee, Jaehoon Jeong, Young-Un Park, Yongdo Kwak, Seol Ae Lee, Haeryun Lee, Hyeon Son, Sang Ki Park
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45618 (2012)
Chromatin remodeling through histone modifications has emerged as a key mechanism in the pathophysiology of psychiatric disorders. Valproate (VPA), a first-line medication for bipolar disorder, is known to have histone deacetylase (HDAC) inhibitor ac
Externí odkaz:
https://doaj.org/article/1d72e1cc41554fa6b21901540eb4aaa1
Autor:
Mathieu Chansard, Jian Wang, Hong Chi Tran, Gernot Neumayer, Su Yeon Shim, Young-Un Park, Camille Belzil, Hoa Thi Le, Sang Ki Park, Minh Dang Nguyen
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14583 (2011)
Cytoskeleton dynamics, membranes trafficking and positioning are essential for the proper functioning of any mammalian cell. The identification of the molecules and mechanisms that allow these cellular processes to interface is vital for understandin
Externí odkaz:
https://doaj.org/article/3dc0156bfd8c435f95952cb783e502d7
Autor:
Jung-Min Oh, Yujin Kang, Jumi Park, Yubin Sung, Dayoung Kim, Yuri Seo, Eun A Lee, Jae Sun Ra, Enkhzul Amarsanaa, Young-Un Park, Seon Young Lee, Jung Me Hwang, Hongtae Kim, Orlando Schärer, Seung Woo Cho, Changwook Lee, Kei-ichi Takata, Ja Yil Lee, Kyungjae Myung
Publikováno v:
Nucleic Acids Research.
DNA double-strand break (DSB) repair via homologous recombination is initiated by end resection. The extent of DNA end resection determines the choice of the DSB repair pathway. Nucleases for end resection have been extensively studied. However, it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e4872204eb805556eb09dc000ad1582
https://doi.org/10.1093/nar/gkad308
https://doi.org/10.1093/nar/gkad308
Autor:
Kyungjae Myung, David Maloney, Sung You Hong, Chan Young Park, Winfried Edelmann, Hee Dong Park, Bijoy P. Mathew, Min Ho Jeon, Kyeryoung Lee, Menghang Xia, Ruili Huang, Srilatha Sakamuru, Mengli Cai, Ganesha Rai, Gene Elliott, Young-Un Park, Jennifer T. Fox, Yongliang Zhang
Impairing the division of cancer cells with genotoxic small molecules has been a primary goal to develop chemotherapeutic agents. However, DNA mismatch repair (MMR)-deficient cancer cells are resistant to most conventional chemotherapeutic agents. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79748eede2c740564ea1c31327dd2da1
https://doi.org/10.1158/0008-5472.c.6508299.v1
https://doi.org/10.1158/0008-5472.c.6508299.v1
Autor:
Kyungjae Myung, David Maloney, Sung You Hong, Chan Young Park, Winfried Edelmann, Hee Dong Park, Bijoy P. Mathew, Min Ho Jeon, Kyeryoung Lee, Menghang Xia, Ruili Huang, Srilatha Sakamuru, Mengli Cai, Ganesha Rai, Gene Elliott, Young-Un Park, Jennifer T. Fox, Yongliang Zhang
Supplemental Figures contains supplementary figures S1-S13. Supplementary Figure S1. The effect of MSH2 deficiency on cell sensitivity to baicalein. Supplementary Figure S2. Baicalein-treated HEC59 cells are deficient in CHK2-regulated S phase checkp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb248ab4b317c8719a75fb0a49e2949
https://doi.org/10.1158/0008-5472.22411812.v1
https://doi.org/10.1158/0008-5472.22411812.v1
Autor:
Gu Kong, Jeong-Yeon Lee, Young-Ha Oh, Kyueng-Whan Min, Ho Lee, Taekwon Son, Hyung-Yong Kim, Jin Park, Hyung-Jun Choi, Young-Un Park, Hee Woon An, Hee-Joo Choi, Mi Kyung Park, Ga-Young Jeong
Histone methyltransferase NSD3 is frequently dysregulated in human cancers, yet the epigenetic role of NSD3 during cancer development remains elusive. Here we report that NSD3-induced methylation of H3K36 is crucial for breast tumor initiation and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d714de7b1d41af7031aa4701966269
https://doi.org/10.1158/0008-5472.c.6512607.v1
https://doi.org/10.1158/0008-5472.c.6512607.v1
Autor:
Kyungjae Myung, David Maloney, Sung You Hong, Chan Young Park, Winfried Edelmann, Hee Dong Park, Bijoy P. Mathew, Min Ho Jeon, Kyeryoung Lee, Menghang Xia, Ruili Huang, Srilatha Sakamuru, Mengli Cai, Ganesha Rai, Gene Elliott, Young-Un Park, Jennifer T. Fox, Yongliang Zhang
This file has detail figure legends for supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19cc831387cf9ecbc5743847a09b8394
https://doi.org/10.1158/0008-5472.22411809
https://doi.org/10.1158/0008-5472.22411809