Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Young-Un Park"'
Autor:
Su Been Lee, Jihyun Park, Yongdo Kwak, Young-Un Park, Truong Thi My Nhung, Bo Kyoung Suh, Youngsik Woo, Yeongjun Suh, Eunbyul Cho, Sehyung Cho, Sang Ki Park
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Disrupted-in-schizophrenia 1 (DISC1) is a scaffold protein that has been implicated in multiple mental disorders. DISC1 is known to regulate neuronal proliferation, signaling, and intracellular calcium homeostasis, as well as neurodevelopmen
Externí odkaz:
https://doaj.org/article/a569f15b88964372a19681cbdbc3d327
Autor:
Jung-Min Oh, Yujin Kang, Jumi Park, Yubin Sung, Dayoung Kim, Yuri Seo, Eun A Lee, Jae Sun Ra, Enkhzul Amarsanaa, Young-Un Park, Seon Young Lee, Jung Me Hwang, Hongtae Kim, Orlando Schärer, Seung Woo Cho, Changwook Lee, Kei-ichi Takata, Ja Yil Lee, Kyungjae Myung
Publikováno v:
Nucleic Acids Research.
DNA double-strand break (DSB) repair via homologous recombination is initiated by end resection. The extent of DNA end resection determines the choice of the DSB repair pathway. Nucleases for end resection have been extensively studied. However, it i
Autor:
Kyungjae Myung, David Maloney, Sung You Hong, Chan Young Park, Winfried Edelmann, Hee Dong Park, Bijoy P. Mathew, Min Ho Jeon, Kyeryoung Lee, Menghang Xia, Ruili Huang, Srilatha Sakamuru, Mengli Cai, Ganesha Rai, Gene Elliott, Young-Un Park, Jennifer T. Fox, Yongliang Zhang
Impairing the division of cancer cells with genotoxic small molecules has been a primary goal to develop chemotherapeutic agents. However, DNA mismatch repair (MMR)-deficient cancer cells are resistant to most conventional chemotherapeutic agents. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79748eede2c740564ea1c31327dd2da1
https://doi.org/10.1158/0008-5472.c.6508299.v1
https://doi.org/10.1158/0008-5472.c.6508299.v1
Autor:
Kyungjae Myung, David Maloney, Sung You Hong, Chan Young Park, Winfried Edelmann, Hee Dong Park, Bijoy P. Mathew, Min Ho Jeon, Kyeryoung Lee, Menghang Xia, Ruili Huang, Srilatha Sakamuru, Mengli Cai, Ganesha Rai, Gene Elliott, Young-Un Park, Jennifer T. Fox, Yongliang Zhang
Supplemental Figures contains supplementary figures S1-S13. Supplementary Figure S1. The effect of MSH2 deficiency on cell sensitivity to baicalein. Supplementary Figure S2. Baicalein-treated HEC59 cells are deficient in CHK2-regulated S phase checkp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb248ab4b317c8719a75fb0a49e2949
https://doi.org/10.1158/0008-5472.22411812.v1
https://doi.org/10.1158/0008-5472.22411812.v1
Autor:
Gu Kong, Jeong-Yeon Lee, Young-Ha Oh, Kyueng-Whan Min, Ho Lee, Taekwon Son, Hyung-Yong Kim, Jin Park, Hyung-Jun Choi, Young-Un Park, Hee Woon An, Hee-Joo Choi, Mi Kyung Park, Ga-Young Jeong
Histone methyltransferase NSD3 is frequently dysregulated in human cancers, yet the epigenetic role of NSD3 during cancer development remains elusive. Here we report that NSD3-induced methylation of H3K36 is crucial for breast tumor initiation and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d714de7b1d41af7031aa4701966269
https://doi.org/10.1158/0008-5472.c.6512607.v1
https://doi.org/10.1158/0008-5472.c.6512607.v1
Autor:
Kyungjae Myung, David Maloney, Sung You Hong, Chan Young Park, Winfried Edelmann, Hee Dong Park, Bijoy P. Mathew, Min Ho Jeon, Kyeryoung Lee, Menghang Xia, Ruili Huang, Srilatha Sakamuru, Mengli Cai, Ganesha Rai, Gene Elliott, Young-Un Park, Jennifer T. Fox, Yongliang Zhang
This file has detail figure legends for supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19cc831387cf9ecbc5743847a09b8394
https://doi.org/10.1158/0008-5472.22411809
https://doi.org/10.1158/0008-5472.22411809
Autor:
Kyungjae Myung, David Maloney, Sung You Hong, Chan Young Park, Winfried Edelmann, Hee Dong Park, Bijoy P. Mathew, Min Ho Jeon, Kyeryoung Lee, Menghang Xia, Ruili Huang, Srilatha Sakamuru, Mengli Cai, Ganesha Rai, Gene Elliott, Young-Un Park, Jennifer T. Fox, Yongliang Zhang
This file has methods used in the study in addition to methods described in the manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54db63a92086813ef466f0345178b825
https://doi.org/10.1158/0008-5472.22411806.v1
https://doi.org/10.1158/0008-5472.22411806.v1
Autor:
Gu Kong, Jeong-Yeon Lee, Young-Ha Oh, Kyueng-Whan Min, Ho Lee, Taekwon Son, Hyung-Yong Kim, Jin Park, Hyung-Jun Choi, Young-Un Park, Hee Woon An, Hee-Joo Choi, Mi Kyung Park, Ga-Young Jeong
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151928dfe64f15d6afb16d6ae71bc61c
https://doi.org/10.1158/0008-5472.22427247.v1
https://doi.org/10.1158/0008-5472.22427247.v1
Autor:
Bo Kyoung Suh, Eunbyul Cho, Jihyun Park, Youngsik Woo, Truong Thi My Nhung, Yeongjun Suh, Yongdo Kwak, Sehyung Cho, Young Un Park, Su Been Lee, Sang Ki Park
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Translational Psychiatry
Translational Psychiatry
Disrupted-in-schizophrenia 1 (DISC1) is a scaffold protein that has been implicated in multiple mental disorders. DISC1 is known to regulate neuronal proliferation, signaling, and intracellular calcium homeostasis, as well as neurodevelopment. Althou
Autor:
Taekwon Son, Hyung Jun Choi, Kyueng-Whan Min, Hee Joo Choi, Jin Park, Young Ha Oh, Young Un Park, Hee Woon An, Gu Kong, Ho Lee, Hyung-Yong Kim, Mi Kyung Park, Jeong-Yeon Lee, Ga Young Jeong
Publikováno v:
Cancer Research. 81:77-90
Histone methyltransferase NSD3 is frequently dysregulated in human cancers, yet the epigenetic role of NSD3 during cancer development remains elusive. Here we report that NSD3-induced methylation of H3K36 is crucial for breast tumor initiation and me