Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Young-Soy Rho"'
Autor:
Hong-Sig Sin, Si-Ho Park, Youn-Ja Kwon, Young-Soy Rho, Eun-Joo Kim, Hye-Sook Han, Soo-Jong Um
Publikováno v:
International Journal of Cancer. 109:58-64
Fenretinide, 4-(N-hydroxyphenyl) retinamide (4-HPR), has demonstrated anticancer activity associated with a favorable toxicity profile and is now being investigated in several clinical trials. However, its plasma levels in patients have been far lowe
Autor:
Hong-Sig Sin, Si-Ho Park, Hye-Sook Han, Soo-Jong Um, Youn-Ja Kwon, Young-Soy Rho, Myoung-Soon Park
Publikováno v:
Chemical and Pharmaceutical Bulletin. 52:501-506
Retinoic acid and its amide derivative, N-(4-hydroxyphenyl)retinamide (4-HPR), have been proposed as chemopreventative and chemotherapeutic agents. However, their low cytotoxic activity and water solubility limit their clinical use. In this study, we
Autor:
Young-Soy Rho, Hye-Sook Han, Youn-Ja Kwon, Soo-Jong Um, Hong-Sig Sin, Jong-Sup Park, Si-Ho Park
Publikováno v:
International Journal of Cancer. 107:1038-1046
Retinoids are natural and synthetic derivatives of vitamin A that have great promise for cancer therapy and chemoprevention. Of the retinoids developed so far, 4-(N-hydroxyphenyl)retinamide (4-HPR or fenretinide) appears to have the best therapeutic
Autor:
Si-Ho Park, Hong-Sig Sin, Soo-Jong Um, Tae-Sung Bae, Hye-Sook Han, Youn-Ja Kwon, Young-Soy Rho
Publikováno v:
Oncology Reports.
Retinoic acid (RA) and sodium butyrate (NaB) have been implicated in the regulation of growth and differentiation in various cancer cells. To produce an agent with the properties of both RA and NaB, a butyryl aminophenyl ester of RA (4-BPRE) was synt
Autor:
Hye-Sook Han, Sun-Young Kim, Eun-Joo Kim, Si-Ho Park, Hong-Sig Sin, Tae-Sung Bae, Jong-Sup Park, Soo-Jong Um, Young-Soy Rho, Youn-Ja Kwon
Publikováno v:
Biologicalpharmaceutical bulletin. 26(10)
4-(N-Hydroxyphenyl)retinamide (also known as 4-HPR or fenretinide), a synthetic amide of all-trans retinoic acid (RA), has been implicated as a promising anticancer agent associated with reducing the toxicity related to RA. However, the low plasma le
Autor:
Jin-Wou Kim, So-Mi Kim Cho, Hong-Sig Sin, Young-Soy Rho, Si-Ho Park, Hye-Sook Han, Soo-Jong Um, Youn-Ja Kwon, Myoung-Soon Park
Publikováno v:
Bioorganicmedicinal chemistry. 11(17)
Retinol (vitamin A) is used as an antiwrinkle agent in the cosmetics industry. However, its photo-instability makes it unsuitable for use in general cosmetic formulations. To improve the photo-stability of retinol, three derivatives (3, 4, and 5) wer
Publikováno v:
ChemInform. 21
Syntheses of phthalide sulfone 2 and naphthalenone 6 followed by new ring annelation methodology of Michael addition using the sulfone anion developed by Hauser-Rhee, furnished linear tetracyclic ring system compound 11. The double bond existing in A
Autor:
Hye-Sook Han, Youn-Ja Kwon, Si-Ho Park, Eun-Joo Kim, Young-Soy Rho, Hong-Sig Sin, Soo-Jong Um
Publikováno v:
International Journal of Cancer; 3/10/2004, Vol. 109 Issue 1, p58-64, 7p
Autor:
Soo-Jong Um, Hye-Sook Han, Youn-Ja Kwon, Si-Ho Park, Young-Soy Rho, Hong-Sig Sin, Jong-Sup Park
Publikováno v:
International Journal of Cancer; 12/20/2003, Vol. 107 Issue 6, p1038, 9p