Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Young-Seok Ju"'
Autor:
Ryosuke Jikuya, Todd A. Johnson, Kazuhiro Maejima, Jisong An, Young-Seok Ju, Hwajin Lee, Kyungsik Ha, WooJeung Song, Youngwook Kim, Yuki Okawa, Shota Sasagawa, Yuki Kanazashi, Masashi Fujita, Seiya Imoto, Taku Mitome, Shinji Ohtake, Go Noguchi, Sachi Kawaura, Yasuhiro Iribe, Kota Aomori, Tomoyuki Tatenuma, Mitsuru Komeya, Hiroki Ito, Yusuke Ito, Kentaro Muraoka, Mitsuko Furuya, Ikuma Kato, Satoshi Fujii, Haruka Hamanoue, Tomohiko Tamura, Masaya Baba, Toshio Suda, Tatsuhiko Kodama, Kazuhide Makiyama, Masahiro Yao, Brian M. Shuch, Christopher J. Ricketts, Laura S. Schmidt, W. Marston Linehan, Hidewaki Nakagawa, Hisashi Hasumi
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104596- (2023)
Summary: Background: Birt-Hogg-Dubé (BHD) syndrome, caused by germline alteration of folliculin (FLCN) gene, develops hybrid oncocytic/chromophobe tumour (HOCT) and chromophobe renal cell carcinoma (ChRCC), whereas sporadic ChRCC does not harbor FLC
Externí odkaz:
https://doaj.org/article/1a1f190403a54532b17c7529b2ef813d
Autor:
Ryul Kim, Seokhwi Kim, Brian Baek-Lok Oh, Woo Sik Yu, Chang Woo Kim, Hoon Hur, Sang-Yong Son, Min Jae Yang, Dae Sung Cho, Taeyang Ha, Subin Heo, Jeon Yeob Jang, Jae Sung Yun, Kyu-Sung Kwack, Jai Keun Kim, Jimi Huh, Sun Gyo Lim, Sang-Uk Han, Hyun Woo Lee, Ji Eun Park, Chul-Ho Kim, Jin Roh, Young Wha Koh, Dakeun Lee, Jang-Hee Kim, Gil Ho Lee, Choong-Kyun Noh, Yun Jung Jung, Ji Won Park, Seungsoo Sheen, Mi Sun Ahn, Yong Won Choi, Tae-Hwan Kim, Seok Yun Kang, Jin-Hyuk Choi, Soo Yeon Baek, Kee Myung Lee, Sun Il Kim, Sung Hyun Noh, Se-Hyuk Kim, Hyemin Hwang, Eunjung Joo, Shinjung Lee, Jong-Yeon Shin, Ji-Young Yun, Junggil Park, Kijong Yi, Youngoh Kwon, Won-Chul Lee, Hansol Park, Joonoh Lim, Boram Yi, Jaemo Koo, June-Young Koh, Sangmoon Lee, Yuna Lee, Bo-Rahm Lee, Erin Connolly-Strong, Young Seok Ju, Minsuk Kwon
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 8, Pp 1856-1868 (2024)
Abstract Genomic alterations in tumors play a pivotal role in determining their clinical trajectory and responsiveness to treatment. Targeted panel sequencing (TPS) has served as a key clinical tool over the past decade, but advancements in sequencin
Externí odkaz:
https://doaj.org/article/18ef47eef5b44df8bf4610ec88fcc2d9
Autor:
Il Bin Kim, Myeong-Heui Kim, Saehoon Jung, Woo Kyeong Kim, Junehawk Lee, Young Seok Ju, Maree J. Webster, Sanghyeon Kim, Ja Hye Kim, Hyun Jung Kim, Junho Kim, Sangwoo Kim, Jeong Ho Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 8, Pp 1750-1762 (2024)
Abstract Low-level somatic mutations in the human brain are implicated in various neurological disorders. The contribution of low-level brain somatic mutations to autism spectrum disorder (ASD), however, remains poorly understood. Here, we performed
Externí odkaz:
https://doaj.org/article/0d5d2a61a356424e91f19af0456c7a2f
Autor:
Byung-Kwan Jeong, Won-Il Choi, Wonsuk Choi, Jieun Moon, Won Hee Lee, Chan Choi, In Young Choi, Sang-Hyun Lee, Jung Kuk Kim, Young Seok Ju, Pilhan Kim, Young-Ah Moon, Jun Yong Park, Hail Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The lack of an appropriate preclinical model of metabolic dysfunction-associated steatotic liver disease (MASLD) that recapitulates the whole disease spectrum impedes exploration of disease pathophysiology and the development of effective tr
Externí odkaz:
https://doaj.org/article/70741e52a40c4025ab35c574807d5ffd
Autor:
Seong Eun Lee, Seongyeol Park, Shinae Yi, Na Rae Choi, Mi Ae Lim, Jae Won Chang, Ho-Ryun Won, Je Ryong Kim, Hye Mi Ko, Eun-Jae Chung, Young Joo Park, Sun Wook Cho, Hyeong Won Yu, June Young Choi, Min-Kyung Yeo, Boram Yi, Kijong Yi, Joonoh Lim, Jun-Young Koh, Min Jeong Lee, Jun Young Heo, Sang Jun Yoon, Sung Won Kwon, Jong-Lyul Park, In Sun Chu, Jin Man Kim, Seon-Young Kim, Yujuan Shan, Lihua Liu, Sung-A Hong, Dong Wook Choi, Junyoung O. Park, Young Seok Ju, Minho Shong, Seon-Kyu Kim, Bon Seok Koo, Yea Eun Kang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The role of the serine/glycine metabolic pathway (SGP) has recently been demonstrated in tumors; however, the pathological relevance of the SGP in thyroid cancer remains unexplored. Here, we perform metabolomic profiling of 17 tumor-normal p
Externí odkaz:
https://doaj.org/article/2830ae43ce6c45ee8260e427839f454f
Autor:
Kabsoo Shin, Ryul Kim, Hansol Park, Wonchul Lee, Sangmoon Lee, Joonoh Im, Ji Eun Lee, Sung Hun Kim, Erin Connolly-Strong, Young Seok Ju, Brian Baek-Lok Oh, Jeongmin Lee
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 317-328 (2024)
Introduction: Breast cancer exhibits vast genomic diversity, leading to varied clinical manifestations. Integrating molecular subtyping with in-depth genomic profiling is pivotal for informed treatment choices and prognostic insights. Whole-genome cl
Externí odkaz:
https://doaj.org/article/163cc040afc14e8e844eef650b620015
Autor:
Christopher J. Yoon, Chang Hyun Nam, Taewoo Kim, Jeong Seok Lee, Ryul Kim, Kijong Yi, June-Young Koh, Jiye Kim, Hyein Won, Ji Won Oh, Obi L. Griffith, Malachi Griffith, Joohon Sung, Tae Yeul Kim, Duck Cho, Ji Seon Choi, Young Seok Ju
Publikováno v:
HGG Advances, Vol 5, Iss 3, Pp 100301- (2024)
Summary: While most dizygotic twins have a dichorionic placenta, rare cases of dizygotic twins with a monochorionic placenta have been reported. The monochorionic placenta in dizygotic twins allows in utero exchange of embryonic cells, resulting in c
Externí odkaz:
https://doaj.org/article/f1dbbd925688474a9c7d70779040690e
Autor:
Jun Hee Cho, Soojin Hwang, Yoon Hae Kwak, Mi‐Sun Yum, Go Hun Seo, June‐Young Koh, Young Seok Ju, Ji‐Hee Yoon, Minji Kang, Hyo‐Sang Do, Soyoung Kim, Gu‐Hwan Kim, Hyunwoo Bae, Beom Hee Lee
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Background Congenital insensitivity to pain with anhidrosis (CIPA) is an extremely rare autosomal recessive disorder caused by loss‐of‐function mutations of the NTRK1 gene, affecting the autonomic and sensory nervous system. Clinical man
Externí odkaz:
https://doaj.org/article/8da963c2676e4fdb90534c447e635132
Autor:
Yong Joon Kim, Hyo Song Park, Jeonghwan Youk, Jung Woo Han, Suk Ho Byeon, Sung Soo Kim, Young Seok Ju, Lee, Christopher Seungkyu
Publikováno v:
British Journal of Ophthalmology; Jul2024, Vol. 108 Issue 7, p1011-1017, 7p
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The C:G > T:A substitution at the CpG dinucleotide contexts is the most frequent substitution type in genome evolution. The mutational process is obviously ongoing in the human germline; however, its impact on common and rare geno
Externí odkaz:
https://doaj.org/article/58342cf4385b481581c51064dd1d4f53