Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Young-Seob Kim"'
Autor:
Kwangmin Na, Seul Lee, Dong Kwon Kim, Young Seob Kim, Joon Yeon Hwang, Seong-san Kang, Sujeong Baek, Chai Young Lee, Seung Min Yang, Yu Jin Han, Mi hyun Kim, Heekyung Han, Youngtaek Kim, Jae Hwan Kim, Seunghyun Jeon, Youngseon Byeon, Jii Bum Lee, Sun Min Lim, Min Hee Hong, Kyoung-Ho Pyo, Byoung Chul Cho
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionTo understand the immune system within the tumor microenvironment (TME) of non-small cell lung cancer (NSCLC), it is crucial to elucidate the characteristics of molecules associated with T cell activation.MethodsWe conducted an in-depth a
Externí odkaz:
https://doaj.org/article/f13ad274bb6e438bb19dd14aedd7d16e
Autor:
Seul Lee, Yunjoo Joo, Eun Ji Lee, Youngseon Byeon, Jae-Hwan Kim, Kyoung-Ho Pyo, Young Seob Kim, Sun Min Lim, Peter Kilbride, Rohin K Iyer, Mingming Li, Mandy C French, Jung-Yub Lee, Jeeheon Kang, Hyesin Byun, Byoung Chul Cho
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0294857 (2024)
Natural killer (NK) cells have recently shown renewed promise as therapeutic cells for use in treating hematologic cancer indications. Despite this promise, NK cell manufacturing workflows remain largely manual, open, and disconnected, and depend on
Externí odkaz:
https://doaj.org/article/f53e29796dd1462dbf5dea557ec090d1
Autor:
Dong Kwon Kim, Chun-Bong Synn, Seung Min Yang, Seongsan Kang, Sujeong Baek, Se-Woong Oh, Gyu-Jin Lee, Ho-Woong Kang, Young-Sung Lee, Jong Suk Park, Jae Hwan Kim, Youngseon Byeon, Young Seob Kim, Doo Jae Lee, Hyun-Woo Kim, June Dong Park, Sung Sook Lee, Ji Yun Lee, Jii Bum Lee, Chang Gon Kim, Min Hee Hong, Sun Min Lim, Hey Ryun Kim, Kyoung-Ho Pyo, Byoung Chul Cho
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Among cancer cells, indoleamine 2, 3-dioxygenase1 (IDO1) activity has been implicated in improving the proliferation and growth of cancer cells and suppressing immune cell activity. IDO1 is also responsible for the catabolism of tryptophan to kynuren
Externí odkaz:
https://doaj.org/article/30185622547a479687c15ffe8e327c40
Autor:
Tae Heung Kang, Jung Hwa Park, Andrew Yang, Hyun Jin Park, Sung Eun Lee, Young Seob Kim, Gun-Young Jang, Emily Farmer, Brandon Lam, Yeong-Min Park, Chien-Fu Hung
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
AnnexinV has been shown to bind phosphatidylserine expressed by chemotherapy-induced apoptotic cells increasing their immunogeneicity. Here, the authors demonstrate in a preclinical tumor model that fusing tumor-antigen peptide to Annexin V enhances
Externí odkaz:
https://doaj.org/article/2fb1fbb0de664cbdac06f9837a479b3c
Autor:
Wongeun Lee, Dong Kwon Kim, Chun-Bong Synn, Hee Kyu Lee, Sungho Park, Dong-Sik Jung, Yewon Choi, Jae Hwan Kim, Youngseon Byeon, Young Seob Kim, Seul Lee, Soyeon Lee, Yunjoo Joo, Eun Ji Lee, Mi Ran Yun, Seong Gu Heo, Wookyeom Yang, Ji Eun Jung, Eun Kyung Kim, Jooyeon Park, June Dong Park, Doo Jae Lee, Hyeon-Woo Kim, Sun Min Lim, Min Hee Hong, Beung-Chul Ahn, Jii Bum Lee, Kyoung-Ho Pyo
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A recently developed treatment strategy for lung cancer that combines immune checkpoint inhibitors with chemotherapy has been applied as a standard treatment for lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), and it has improved
Externí odkaz:
https://doaj.org/article/407f5970dae34dc5907c67d56bd5e79e
Autor:
Chun‐Bong Synn, Sung Eun Kim, Hee Kyu Lee, Min‐Hwan Kim, Jae Hwan Kim, Ji Min Lee, Ha Ni Jo, Wongeun Lee, Dong Kwon Kim, Youngseon Byeon, Young Seob Kim, Mi Ran Yun, Chae‐Won Park, Jiyeon Yun, Sangbin Lim, Seong Gu Heo, San‐Duk Yang, Eun Ji Lee, Seul Lee, Hunmi Choi, You Won Lee, Jae Seok Cho, Do Hee Kim, Sungho Park, Jung‐Ho Kim, Yewon Choi, Sung Sook Lee, Beung‐Chul Ahn, Chang Gon Kim, Sun Min Lim, Min Hee Hong, Hye Ryun Kim, Kyoung‐Ho Pyo, Byoung Chul Cho
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives AXL‐mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment. We evaluated the anti‐tumor and anti‐metastatic activities of SKI‐G‐801, a sma
Externí odkaz:
https://doaj.org/article/2810ccf729dc4cf68402dc5c21aa1ea6
Autor:
Tae Heung Kang, Chih-Ping Mao, Young Seob Kim, Tae Woo Kim, Andrew Yang, Brandon Lam, Ssu-Hsueh Tseng, Emily Farmer, Yeong-Min Park, Chien-Fu Hung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract The tumor microenvironment exists in a state of dynamic equilibrium, in which a balance of agonist and antagonist signals govern the anti-tumor immune responses. Previous studies have shown that chemotherapy could shift this balance in favor
Externí odkaz:
https://doaj.org/article/d7b47040938045bbad53169253d14929
Autor:
Chanyoung Song, Hathaichanok Phuengkham, Young Seob Kim, Van Vuong Dinh, Inho Lee, Il Woo Shin, Hong Sik Shin, Seung Mo Jin, Soong Ho Um, Hyunseung Lee, Kwan Soo Hong, Seon-Mi Jin, Eunji Lee, Tae Heung Kang, Yeong-Min Park, Yong Taik Lim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The limited efficacy of current immunotherapy suggests low antigen-specific T cells and immunosuppressive factors in tumor microenvironment (TME). Here, the authors develop a syringeable immunomodulatory multi-domain nanogel that can reprogram the TM
Externí odkaz:
https://doaj.org/article/74f56ede70494663b8680f81b8197124
Autor:
Hyun Jin Park, Gun-Young Jang, Young Seob Kim, Jung Hwa Park, Sung Eun Lee, Manh-Cuong Vo, Je-Jung Lee, Hee Dong Han, In Duk Jung, Tae Heung Kang, Yeong-Min Park
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Dendritic cells (DCs) are professional antigen presenting cells (APCs), which can activate antigen-specific CD8+ T cell immunity, resulting in tumor clearance. Immature DCs are usually stimulated by various adjuvants through their
Externí odkaz:
https://doaj.org/article/1cd143757e744b09a088290bbaa52a8e
Autor:
Jung Hwa Park, Jong-Hwa Jang, Eun Jung Choi, Young Seob Kim, Eun Ji Lee, In Duk Jung, Hee Dong Han, T-C Wu, Chien-Fu Hung, Tae Heung Kang, Yeong-Min Park
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 424-436 (2016)
Abstract The identification of HMGB1 as a late mediator in sepsis has highlighted HMGB1 as a promising therapeutic target for sepsis treatment. Recent studies have revealed that annexin A5, a 35 kDa Ca2+-dependent phospholipid binding protein, exerts
Externí odkaz:
https://doaj.org/article/56cf02dc4d60458c974599993a52b308