Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Young-Ping Hwung"'
Publikováno v:
Journal of Biological Chemistry. 266:18179-18187
The activation of gene transcription by nuclear receptors is invariably associated with alterations in chromatin structure at hormone-responsive elements of target genes. To identify the molecular functions underlying receptor-mediated chromatin stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebb2e805e1135b7de614b686470daf73
https://doi.org/10.1016/s0021-9258(18)55252-2
https://doi.org/10.1016/s0021-9258(18)55252-2
Publikováno v:
Molecular and Cellular Biology. 10:1784-1788
The 5'-flanking region of the rat insulin II gene (-448 to +50) is sufficient for tissue-specific expression. To further determine the tissue-specific cis-acting element(s), important sequences defined by linker-scanning mutagenesis were placed upstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302fcc685b3966e1a841d24c739f75a2
https://doi.org/10.1128/mcb.10.4.1784
https://doi.org/10.1128/mcb.10.4.1784
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 6(7)
The estrogen receptor (ER) is a transcription factor involved in steroid hormone signal transduction in higher eukaryotes. The receptor also functions as a ligand-dependent transcriptional activator when introduced into Saccharomyces cerevisiae (bake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fee9590432376b2d81b1b8b95bece5
https://pubmed.ncbi.nlm.nih.gov/1508220
https://pubmed.ncbi.nlm.nih.gov/1508220
Publikováno v:
Journal of Biological Chemistry. 263:13470-13474
The COUP (chicken ovalbumin upstream promoter) transcription factor binds to the upstream promoters of both the chicken ovalbumin and the rat insulin II genes, even though the two binding sites have no obvious sequence similarity (Hwung, Y.-P., Crowe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6488bd704e790912a683fa8efea67e0a
https://doi.org/10.1016/s0021-9258(18)37729-9
https://doi.org/10.1016/s0021-9258(18)37729-9
Publikováno v:
Molecular and Cellular Biology. 8:2070-2077
Band-shifting and DNase I-footprinting assays have been used to study the trans-acting factor(s) binding to an important promoter element (-53 to -46 relative to the transcription start) of the rat insulin II gene. A binding activity which footprints
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da0de25873ac166b3e64f770987d618
https://doi.org/10.1128/mcb.8.5.2070
https://doi.org/10.1128/mcb.8.5.2070
Publikováno v:
Gene Regulation by Steroid Hormones IV ISBN: 9781461281979
Insulin is one of the key peptide hormones in the control of growth and metabolism. The imbalance of insulin action results in diabetes mellitus which has broad impact on the society. Aside from its medical importance, the insulin gene is interesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d218364ff1f81b087c76cd0feedbdcd
https://doi.org/10.1007/978-1-4612-3666-5_8
https://doi.org/10.1007/978-1-4612-3666-5_8
