Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Young-Lim Shim"'
Autor:
Ha-Lim Song, Na-Young Kim, Jaewan Park, Meong Il Kim, Yu-Na Jeon, Se-Jong Lee, Kwangmin Cho, Young-Lim Shim, Kyoung-Hye Lee, Yeon-Seon Mun, Jung-A Song, Min-Seok Kim, Chan-Gi Pack, Minkyo Jung, Hyemin Jang, Duk L. Na, Minsun Hong, Dong-Hou Kim, Seung-Yong Yoon
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
The spatiotemporal pattern of the spread of pathologically modified tau through brain regions in Alzheimer’s disease (AD) can be explained by prion-like cell-to-cell seeding and propagation of misfolded tau aggregates. Hence, to develop targeted th
Externí odkaz:
https://doaj.org/article/77c533ffd920419dbb5df9f87c1220e9
Autor:
Hyunju Kim, Seung-Yong Yoon, Na Young Kim, Ha-Lim Song, Minseok Kim, Seung Eun Lee, Dong-Hou Kim, Yeon-Seon Mun, Young-Lim Shim, Kyounghye Lee, Kwangmin Cho
Background : Tau is gaining attention as a target of therapeutic antibodies for Alzheimer's disease (AD) and other tauopathies but it was recently of debate which epitope on tau has therapeutic potency. While the hexapeptide 275VQIINK280 is a critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a94b86bd81350e6fe8fa30ce3ee58d51
https://doi.org/10.21203/rs.3.rs-100198/v1
https://doi.org/10.21203/rs.3.rs-100198/v1
Autor:
Se-Jong Lee, Dong-Hou Kim, Kwangmin Cho, Seung-Yong Yoon, Young-Lim Shim, Da-Som Lim, Ji-Yong Lee, You-Jin Jang, Yu-Na Jeon
Publikováno v:
Biochemical and biophysical research communications. 524(3)
β-Amyloid (Aβ) plaque in the brains of patients with Alzheimer's disease (AD) is mainly caused by impaired clearance of Aβ by glial cells, including microglia and astrocytes. Because microglia play an important protective role in the central nervo