Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Young-Ki Paik"'
Autor:
Seokwon Lee, Mingu Kang, Seungwoo Lee, Sangsun Yoon, Yeonjin Cho, Dongjae Min, Daye Ann, Jisoo Shin, Young-Ki Paik, Daewoong Jo
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107326- (2024)
Neurodegenerative disorders, such as Parkinson's disease (PD) and Alzheimer's disease (AD), have a global prevalence and profoundly impact both motor and cognitive functions. Although adeno-associated virus (AAV)-based gene therapy has shown promise,
Externí odkaz:
https://doaj.org/article/8f6146f5ef7943478e92efe6870a44d1
Autor:
Mingu Kang, Seokwon Lee, Jong-pil Seo, Eun-bee Lee, Daye Ahn, Jisoo Shin, Young-Ki Paik, Daewoong Jo
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100983- (2024)
The use of the FDA-approved osteoinductive growth factor BMP2 is widespread for bone regeneration. However, its clinical application has been hindered by limitations in cell permeability and a short half-life in circulation. To address this issue, we
Externí odkaz:
https://doaj.org/article/1b77ceb26c3e4c9c92dcbc8e9b386a3f
Autor:
Munseok Choi, Minsu Park, Sung Hwan Lee, Min Jung Lee, Young‐Ki Paik, Sung Il Jang, Dong Ki Lee, Sang‐Guk Lee, Chang Moo Kang
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 15933-15944 (2023)
Abstract Background Carbohydrate antigen (CA) 19–9 is a known pancreatic cancer (PC) biomarker, but is not commonly used for general screening due to its low sensitivity and specificity. This study aimed to develop a serum metabolites‐based diagn
Externí odkaz:
https://doaj.org/article/986686dd40004bf18729d315d9d8be5c
Autor:
Heeseung Yang, Daehan Lee, Heekyeong Kim, Cook, Daniel E., Young-Ki Paik, Andersen, Erik C., Junho Lee
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/9/2024, Vol. 121 Issue 28, p1-9, 26p
Autor:
Subash Adhikari, Edouard C. Nice, Eric W. Deutsch, Lydie Lane, Gilbert S. Omenn, Stephen R. Pennington, Young-Ki Paik, Christopher M. Overall, Fernando J. Corrales, Ileana M. Cristea, Jennifer E. Van Eyk, Mathias Uhlén, Cecilia Lindskog, Daniel W. Chan, Amos Bairoch, James C. Waddington, Joshua L. Justice, Joshua LaBaer, Henry Rodriguez, Fuchu He, Markus Kostrzewa, Peipei Ping, Rebekah L. Gundry, Peter Stewart, Sanjeeva Srivastava, Sudhir Srivastava, Fabio C. S. Nogueira, Gilberto B. Domont, Yves Vandenbrouck, Maggie P. Y. Lam, Sara Wennersten, Juan Antonio Vizcaino, Marc Wilkins, Jochen M. Schwenk, Emma Lundberg, Nuno Bandeira, Gyorgy Marko-Varga, Susan T. Weintraub, Charles Pineau, Ulrike Kusebauch, Robert L. Moritz, Seong Beom Ahn, Magnus Palmblad, Michael P. Snyder, Ruedi Aebersold, Mark S. Baker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The Human Proteome Project (HPP) was launched in 2010 to enhance accurate annotation of the genome-encoded proteome. Ten years later, the HPP releases its first blueprint of the human proteome, annotating 90% of all known proteins at high-stringency
Externí odkaz:
https://doaj.org/article/bb037a5bb053476e9a3946b7578e5277
Autor:
Donha Park, Jeong-Hoon Hahm, Saeram Park, Go Ha, Gyeong-Eon Chang, Haelim Jeong, Heekyeong Kim, Sunhee Kim, Eunji Cheong, Young-Ki Paik
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Animals use pheromones as a conspecific chemical language to respond appropriately to environmental changes. The soil nematode Caenorhabditis elegans secretes ascaroside pheromones throughout the lifecycle, which influences entry into dauer
Externí odkaz:
https://doaj.org/article/4c270f64486946e9a070a143e78034ee
Autor:
Daehan Lee, Heeseung Yang, Jun Kim, Shannon Brady, Stefan Zdraljevic, Mostafa Zamanian, Heekyeong Kim, Young-ki Paik, Leonid Kruglyak, Erik C. Andersen, Junho Lee
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nematodes use a characteristic set of movements, called nictation, to hitchhike on more mobile animals. Here, Lee et al. identify a genetic locus in the nematode Caenorhabditis elegans that underlies nictation and contributes to successful hitchhikin
Externí odkaz:
https://doaj.org/article/4ba1488f21fe4dde9532631e58b8f14c
Autor:
Young-Ki Paik, Hoguen Kim, Chang Moo Kang, Eun Kyung Kim, Chae-Yeon Kim, Jin-Young Cho, Min Jung Lee, Keun Na, Hyun-Jeong Cha, Heon Shin
This file contains all Supplementary figures visualizing results from differential expression analyses, MS and tandem MS/MS spectrum, establishment of mutant cell lines, localization and promoter binding efficiency.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00be010d149387074e45f7df0a9d2771
https://doi.org/10.1158/0008-5472.22418699.v1
https://doi.org/10.1158/0008-5472.22418699.v1
Autor:
Young-Ki Paik, Hoguen Kim, Chang Moo Kang, Eun Kyung Kim, Chae-Yeon Kim, Jin-Young Cho, Min Jung Lee, Keun Na, Hyun-Jeong Cha, Heon Shin
This file contains all detailed Supplementary Material and Methods from this research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c80c21ddd60ea48be723e8e4a2cb7e
https://doi.org/10.1158/0008-5472.22418696
https://doi.org/10.1158/0008-5472.22418696
Autor:
Young-Ki Paik, Hoguen Kim, Chang Moo Kang, Eun Kyung Kim, Chae-Yeon Kim, Jin-Young Cho, Min Jung Lee, Keun Na, Hyun-Jeong Cha, Heon Shin
Posttranslational modifications of tumor suppressors can induce abnormal cell growth. Here, we identify site-specific O-GlcNAcylation as a critical block of FOXO3 that may abrogate a part of the p53 pathway, resulting in aberrant cancer cell growth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2efd51f3ed3e57a127ad9797a2f3f1a
https://doi.org/10.1158/0008-5472.c.6510200.v1
https://doi.org/10.1158/0008-5472.c.6510200.v1