Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Young-Kee Shin"'
Autor:
Wenxiao Wang, Yaqi Wang, Feifei Yin, Hongsen Niu, Young-Kee Shin, Yang Li, Eun-Seong Kim, Nam-Young Kim
Publikováno v:
Nano-Micro Letters, Vol 16, Iss 1, Pp 1-16 (2024)
Highlights An optoelectronic memristor with bioinspired neuromorphic behavior was proposed based on Ag/TiO2 Nanowires: ZnO QDs/FTO. The proposed device establishes superior long/short-term synaptic plasticity in response to electrical and light stimu
Externí odkaz:
https://doaj.org/article/f71bcc21e3db4584a038b7d676af4745
Autor:
Nirmal Rajasekaran, Kyoung Song, Jin-Hee Lee, Yun Wei, Özgür Cem Erkin, Hunseok Lee, Young-Kee Shin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5595 (2021)
SMAD4, a key regulator of transforming growth factor-β (TGF-β) signaling, plays a major role in cell growth, migration, and apoptosis. In particular, TGF-β/SMAD induces growth arrest, and SMAD4 induces the expression of target genes such as p21WAF
Externí odkaz:
https://doaj.org/article/dac5a3fef66845329ef7f5cf56577e81
Autor:
Hu-Quan Yin, Young-Tae Je, Young-Chul Kim, Young-Kee Shin, SangHyun Sung, KiYong Lee, Gil-Saeng Jeong, Youn-Chul Kim, Byung-Hoon Lee
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 4, Pp 486-495 (2009)
The generally accepted hypothesis for the pathogenesis of alcoholic liver disease (ALD) is the two-hit model, which proposes that fat accumulation in the liver increases the sensitivity of the liver to a second hit that leads to inflammatory liver ce
Externí odkaz:
https://doaj.org/article/6a0aea11e4c940d7b8856bf269c8e290
Autor:
Seung Yeob Hyun, Hye-Young Min, Ho Jin Lee, Jaebeom Cho, Hye-Jin Boo, Myungkyung Noh, Hyun-Ji Jang, Hyo-Jong Lee, Choon-Sik Park, Jong-Sook Park, Young Kee Shin, Ho-Young Lee
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role of Ninj1 in the contex
Externí odkaz:
https://doaj.org/article/b4f3869aff0848ca82a6e321d2e20bea
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 6, Pp 2647-2693 (2018)
Cancer is a disease caused by the accumulation of genetic and epigenetic changes in two types of genes: tumor suppressor genes (TSGs) and proto-oncogenes. Extensive research has been conducted over the last few decades to elucidate the role of TSGs i
Externí odkaz:
https://doaj.org/article/a57a8564154e4a308f19f537fd40faa1
Autor:
Ji-Hye Nam, Min-Soo Kim, Young-Jo Song, Chang-Hwan Kim, Wang Soo Kim, Chi Ho Yu, Hae Eun Joe, Gyeung Haeng Hur, Myeung-Ryun Seo, Yeongmun Kim, Kyung Eui Park, Jun Young Choi, Suk-Jae Chung, Young Kee Shin
Publikováno v:
Archives of Toxicology. 97:697-710
Autor:
Su Jung Hwang, Hye-Young Min, Rang Woon Park, Jaebeom Cho, Ho-Young Lee, Mien Chie Hung, Hyo Jong Lee, Ho Jin Lee, Jeong Yeon Sim, Myungkyung Noh, Shin-Hyung Park, Seung Yeob Hyun, Hye-Jin Boo, Sungyoul Hong, Young Kee Shin
Publikováno v:
J Clin Invest
Slow-cycling/dormant cancer cells (SCCs) have pivotal roles in driving cancer relapse and drug resistance. A mechanistic explanation for cancer cell dormancy and therapeutic strategies targeting SCCs are necessary to improve patient prognosis, but ar
Autor:
Kyoung Song, Hun Seok Lee, Lina Jia, Chaithanya Chelakkot, Nirmal Rajasekaran, Young Kee Shin
Publikováno v:
Molecules and Cells. 45:413-424
Suppressor of mothers against decapentaplegic homolog (SMAD) 4 is a pluripotent signaling mediator that regulates myriad cellular functions, including cell growth, cell division, angiogenesis, apoptosis, cell invasion, and metastasis, through transfo
Autor:
Young Kee Shin, Yoon-La Choi, Ho Bin Yang, Seoung Wan Chae, Jong-Sun Choi, Özgür Cem Erkin, Li-Hui Wang, Ryong Nam Kim, Sang Gyu Park, Juthika Kundu, Chun Fu Wu, Hun Seok Lee, Lina Jia
Supplementary Figure 1B . AGS, SW480, and HeLa cells were pretreated with control siRNA (lane 1 and 2) or AURKA siRNA (10 nM, lane 3 and 4) for 48 h, and transfected with the plasmid encoding 6Myc-SMAD4 or empty vector. Cells were collected 24 h afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343a528041a6aab087a1ec90a14b3505
https://doi.org/10.1158/1541-7786.22511841.v1
https://doi.org/10.1158/1541-7786.22511841.v1
Autor:
Young Kee Shin, Yoon-La Choi, Ho Bin Yang, Seoung Wan Chae, Jong-Sun Choi, Özgür Cem Erkin, Li-Hui Wang, Ryong Nam Kim, Sang Gyu Park, Juthika Kundu, Chun Fu Wu, Hun Seok Lee, Lina Jia
SMAD4 has been suggested to inhibit the activity of the WNT/β-catenin signaling pathway in cancer. However, the mechanism by which SMAD4 antagonizes WNT/β-catenin signaling in cancer remains largely unknown. Aurora A kinase (AURKA), which is freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac3f6943721b16167b230b877cf788e
https://doi.org/10.1158/1541-7786.c.6540054.v1
https://doi.org/10.1158/1541-7786.c.6540054.v1