Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Young-Jai You"'
Autor:
Cecilia Yip, Steven C. Wyler, Katrina Liang, Shin Yamazaki, Tyler Cobb, Maryam Safdar, Aarav Metai, Warda Merchant, Robert Wessells, Adrian Rothenfluh, Syann Lee, Joel Elmquist, Young-Jai You
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101939- (2024)
Objective: Metamorphosis is a transition from growth to reproduction, through which an animal adopts adult behavior and metabolism. Yet the neural mechanisms underlying the switch are unclear. Here we report that neuronal E93, a transcription factor
Externí odkaz:
https://doaj.org/article/4f07b5ce04e1407fa8d65a653ea162aa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Kim et al. show noradrenergic signaling for stress responses such as flight and fight, also serves as a conserved signal for maintaining oocyte quiescence under unfavorable conditions in worms, flies, and fish.
Externí odkaz:
https://doaj.org/article/efe801b239154b698e1339379dcd5771
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Sleep and metabolism are interconnected homeostatic states; the sleep cycle can be entrained by the feeding cycle, and perturbation of the sleep often results in dysregulation in metabolism. However, the neuro-molecular mechanism by which metabolism
Externí odkaz:
https://doaj.org/article/e35719e1df8948678a309d4d28de7c98
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract Appropriate decision-making is essential for ensuring survival; one such decision is whether to eat. Overall metabolic state and the safety of food are the two factors we examined using C. elegans to ask whether the metabolic state regulates
Externí odkaz:
https://doaj.org/article/2fd70b769a934a908dbae8e741991abf
Publikováno v:
eLife, Vol 4 (2015)
Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of
Externí odkaz:
https://doaj.org/article/ba7a418d312c485087fb8a81df836014
Autor:
Zhu Wang, Jonathan Stoltzfus, Young-Jai You, Najju Ranjit, Hao Tang, Yang Xie, James B Lok, David J Mangelsdorf, Steven A Kliewer
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005027 (2015)
Appropriate nutrient response is essential for growth and reproduction. Under favorable nutrient conditions, the C. elegans nuclear receptor DAF-12 is activated by dafachronic acids, hormones that commit larvae to reproductive growth. Here, we report
Externí odkaz:
https://doaj.org/article/4acc9a0bf6984c578e1a297742034c89
Publikováno v:
PLoS ONE, Vol 8, Iss 1 (2013)
Externí odkaz:
https://doaj.org/article/d7b8395c42ad4c0d8f8b8f5c6341bb21
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59865 (2013)
We develop a new hidden Markov model-based method to analyze C elegans locomotive behavior and use this method to quantitatively characterize behavioral states. In agreement with previous work, we find states corresponding to roaming, dwelling, and q
Externí odkaz:
https://doaj.org/article/b29c810dcb9d4000a7e56ad2d8899066
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44720 (2012)
Animals have to cope with starvation. The molecular mechanisms by which animals survive long-term starvation, however, are not clearly understood. When they hatch without food, C. elegans arrests development at the first larval stage (L1) and survive
Externí odkaz:
https://doaj.org/article/7cdced7cec7e4a6c836bed56e1160d63
Autor:
Cecilia Yip, Steven Wyler, Shin Yamazaki, Adrian Rothenfluh, Syann Lee, Young-Jai You, Joel Elmquist
Metamorphosis is a transition from growth to reproduction, through which an animal adopts adult behavior and metabolism. Yet the mechanisms underlying the switch is unclear. Here we report that neuronalE93, a transcription factor essential for metamo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4cf15c6f0b4385629fbc71088562029
https://doi.org/10.1101/2022.10.06.511196
https://doi.org/10.1101/2022.10.06.511196
