Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Young-Hyun Yoo"'
Autor:
Hyun-Seok Jin, Jeonghyun Kim, Sangwook Park, Eunkuk Park, Bo-Young Kim, Vit-Na Choi, Young-Hyun Yoo, Bom-Taeck Kim, Seon-Yong Jeong
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135285 (2015)
To identify novel susceptibility variants for osteoporosis in Korean postmenopausal women, we performed a genome-wide association analysis of 1180 nonsynonymous single nucleotide polymorphisms (nsSNPs) in 405 individuals with osteoporosis and 722 nor
Externí odkaz:
https://doaj.org/article/5649eb2f2ac345ad85cbc6b67b9a0543
Autor:
Young Hyun Yoo, Sung-Heun Kim, Do-Young Kang, Wol Soon Jo, Young Hwa Soung, Na Young Jeong, Jee Hyun Rho, Sang Yull Lee, Tae-Hyun Kim
In the present study, we identified a missense mutation (G199V) in KAT-18 cell line established from primary cultures of anaplastic thyroid cancer (ATC). Notably, knockdown of this mutant (mt) p53 reduced cell viability and exerted antitumor activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22521456479a079e98166c7ed8ed31b5
https://doi.org/10.1158/1541-7786.c.6542670
https://doi.org/10.1158/1541-7786.c.6542670
Autor:
Young Hyun Yoo, Sung-Heun Kim, Do-Young Kang, Wol Soon Jo, Young Hwa Soung, Na Young Jeong, Jee Hyun Rho, Sang Yull Lee, Tae-Hyun Kim
Supplementary Data from Mutant p53 (G199V) Gains Antiapoptotic Function through Signal Transducer and Activator of Transcription 3 in Anaplastic Thyroid Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c432230b27319ba768346ae5e39dcdf
https://doi.org/10.1158/1541-7786.22520529
https://doi.org/10.1158/1541-7786.22520529
Autor:
Ji Sook Kang, Il-Whan Choi, Min Ho Han, Dae-Sung Lee, Gi-Young Kim, Hye Jin Hwang, Byung Woo Kim, Cheol Min Kim, Young Hyun Yoo, Yung Hyun Choi
Publikováno v:
Marine Drugs, Vol 13, Iss 5, Pp 2666-2679 (2015)
This study was designed to examine the protective effects of the marine brown algae Petalonia binghamiae against oxidative stress-induced cellular damage and to elucidate the underlying mechanisms. P. binghamiae methanol extract (PBME) prevented hydr
Externí odkaz:
https://doaj.org/article/8ad37bb6ffcb40ce8b692a1046a85cc1
Autor:
Yoon-Jae Kim, Ji-Eun Park, Jin-Yong Chung, Ji Young Kim, Seung Gee Lee, Seung-Jin Lee, Wook-Joon Yu, Hye Young Kim, Hyeon Jun Kim, Hyungjong Koh, Hae-Rahn Bae, Young Hyun Yoo, Jong-Min Kim
Publikováno v:
The Journal of toxicological sciences. 47(8)
Testicular Leydig cells produce testosterone through the participation of steroidogenic proteins. The CYP1B1 enzyme has been shown to catalyze 7,12-dimethylbenzanthracene (DMBA), a representative polycyclic aromatic hydrocarbon. We hypothesized that
Autor:
Yung Hyun Choi, Young Hyun Yoo, Nam Deuk Kim, Wun-Jae Kim, Gi-Young Kim, Hee-Jae Cha, Hyun Soo Park, Hye Jin Hwang
Publikováno v:
Marine Drugs, Vol 11, Iss 7, Pp 2347-2364 (2013)
The present study investigated possible mechanisms on the apoptosis induction of human leukemic cells by fucoidan, a sulfated polysaccharide found in marine algae. Fucoidan treatment of cells resulted in inhibition of growth and induction of apoptosi
Externí odkaz:
https://doaj.org/article/9663e2907aef49abb685dbfc68c9a7b0
Publikováno v:
Developmentreproduction. 26(2)
In response to luteinizing hormone (LH), a higher concentration of progesterone (P4) is produced in luteal cells of corpus luteum (CL). Mitochondria are an essential cellular organelle in steroidogenesis. The specific engagement of the concept regard
Autor:
Hye Young Kim, Doh Hoon Kim, Ji Eun Park, Jong-Min Kim, Kwang Sik Lee, Joon Beom Park, Young Hyun Yoo, Won Tae Yang, Yeon Jae Jeong
Publikováno v:
Development & Reproduction
Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance (IR). T2DM is correlated with obesity and most T2DM medications have been developed for enhancing insulin sensitivity. Silk protein fibroin (SPF) from spiders has been suggested a
Autor:
Jin Yong Chung, Yoon Jae Kim, Ji Eun Park, Seung Gee Lee, Jiyoung Kim, Jeanho Yun, Seon-Yong Jeong, Hyongjong Koh, Young Hyun Yoo, Hwan Tae Park, Jong-Min Kim
Publikováno v:
Endocrinology. 160:729-743
The initial steps of steroidogenesis occur in the mitochondria. Dynamic changes in the mitochondria are associated with their fission and fusion. Therefore, understanding the cellular and molecular relationships between steroidogenesis and mitochondr
Autor:
Cheol-Hong Kim, Young Hyun Yoo, Jae Yeob Jeong, Hye-Jin Hwang, Yung Hyun Choi, Hee-Jae Cha, Hyun Min Yoon, Gi-Young Kim, Hwan Tae Park, Eun Ok Choi
Publikováno v:
International Journal of Medical Sciences. 16:145-155
Baicalein, a flavonoid extracted from the roots of Scutellaria baicalensis Georgi., has various pharmacological effects due to its high antioxidant activity. However, no study has yet been conducted on the protective efficacy of baicalein against oxi