Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Young-Eun Cho"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Sarcomas, malignant tumors from mesenchymal tissues, exhibit poor prognosis despite advancements in treatment modalities such as surgery, radiotherapy, and chemotherapy, with doxorubicin being a cornerstone treatment. Resistance to doxorubic
Externí odkaz:
https://doaj.org/article/21f890e2a3414a9498dfc915e001c148
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background Abnormal amyloid β (Aβ) deposits in the brain are a hallmark of Alzheimer’s disease (AD). Insufficient sleep duration and poor sleep quality are risk factors for developing AD. Sleep may play a role in Aβ regulation, but the
Externí odkaz:
https://doaj.org/article/942e143331b84290914132c91d81bd74
Autor:
Ji-Soo Jeong, Jeong-Won Kim, Jin-Hwa Kim, Chang-Yeop Kim, Eun-Hye Chung, Young-Eun Cho, Eui-Ju Hong, Hyo-Jung Kwon, Je-Won Ko, Tae-Won Kim
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103193- (2024)
Obesity is associated with an increased incidence of asthma. However, the mechanisms underlying this association are not fully understood. In this study, we investigated the role of thioredoxin-interacting protein (TXNIP) in obesity-induced asthma. A
Externí odkaz:
https://doaj.org/article/981514e716824ea0b9aceddfc5ab5282
Autor:
Kang Ju Jeong, Moeka Mukae, Sang R. Lee, Sang-Yun Kim, Seong Hyeon Kim, Young-Eun Cho, Beum-Soo An, Je-Won Ko, Hyo-Jung Kwun, In-Jeoung Baek, Eui-Ju Hong
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116281- (2024)
Progesterone (P4) is a crucial reproductive hormone that acts as a precursor for all other endogenous steroids. P4 modulates transcriptional activity during reproduction by binding to progesterone receptors (PR). However, the physiological role of P4
Externí odkaz:
https://doaj.org/article/ccb48a4b19f34727a230a4a019f3b2d6
Autor:
Soon-Chan Kim, Young-Eun Cho, Young-Kyoung Shin, Hyeon Jong Yu, Tamrin Chowdhury, Sojin Kim, Kyung Sik Yi, Chi-Hoon Choi, Sang-Hoon Cha, Chul-Kee Park, Ja-Lok Ku
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-15 (2023)
Abstract Glioblastoma (GBM) is the most lethal intracranial tumor. Sequencing technologies have supported personalized therapy for precise diagnosis and optimal treatment of GBM by revealing clinically actionable molecular characteristics. Although a
Externí odkaz:
https://doaj.org/article/d8555ba98b0944cc98c9445c006e11d0
Publikováno v:
Nutrients, Vol 16, Iss 2, p 291 (2024)
Inorganic phosphate (Pi) is a critical determinant of calcification, and its concentration is regulated by alkaline phosphatase (ALP) and Pit1. ALP is a key regulator of osteogenic calcification and acts by modulating local inorganic phosphate (Pi) c
Externí odkaz:
https://doaj.org/article/9d86c31a6879454792eabc9b03ab39db
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 100 (2024)
Background: Middle-aged adults have the highest obesity rates, leading to significant health complications in later years. Obesity triggers the release of altered molecules, including extracellular vesicles (EVs) from excess adipose tissue (AT), cont
Externí odkaz:
https://doaj.org/article/a040494273894818a512d5608588420b
Autor:
Dong-ha Kim, Ji-Su Kim, Jae-Hee Kwon, In-Sook Kwun, Moon-Chang Baek, Gi-Seok Kwon, Wiramon Rungratanawanich, Byoung-Joon Song, Do-Kyun Kim, Hyo-Jung Kwon, Young-Eun Cho
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1886 (2023)
Inflammatory bowel disease (IBD) affects millions of people worldwide and is considered a significant risk factor for colorectal cancer. Recent in vivo and in vitro studies reported that ellagic acid (EA) exhibits important antioxidant and anti-infla
Externí odkaz:
https://doaj.org/article/16185a90c64e467db0fc2210cb5cb1de
Autor:
Soon-Chan Kim, Young-Eun Cho, Young-Kyoung Shin, Hyeon Jong Yu, Tamrin Chowdhury, Sojin Kim, Kyung Sik Yi, Chi-Hoon Choi, Sang-Hoon Cha, Chul-Kee Park, Ja-Lok Ku
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/06079cf06b3246b991fb303c4619e453
Autor:
Do-Kyun Kim, Geethani Bandara, Young-Eun Cho, Hirsh D. Komarow, Danielle R. Donahue, Baktiar Karim, Moon-Chang Baek, Ho Min Kim, Dean D. Metcalfe, Ana Olivera
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Osteoporosis and bone disease are common in patients with systemic mastocytosis. Here, the authors show that extracellular vesicles released by neoplastic mast cells of the patients block osteoblast differentiation and bone mineralization when inject
Externí odkaz:
https://doaj.org/article/5187de6573944f56922f41e7869f5c9c