Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Young-Eui Kim"'
Autor:
Woo-Chang Chung, Subramaniyam Ravichandran, Daegyu Park, Gwang Myeong Lee, Young-Eui Kim, Youngju Choi, Moon Jung Song, Kyeong Kyu Kim, Jin-Hyun Ahn
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011095 (2023)
G-quadruplex (G4) formed by repetitive guanosine-rich sequences plays important roles in diverse cellular processes; however, its roles in viral infection are not fully understood. In this study, we investigated the genome-wide distribution of G4-for
Externí odkaz:
https://doaj.org/article/e3d756401a8044f3bf462c33251ac39d
Autor:
Kye Ryeong Park, Young-Eui Kim, Amen Shamim, Shuang Gong, Soo-Han Choi, Kyeong Kyu Kim, Yae-Jean Kim, Jin-Hyun Ahn
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The appearance of drug-resistant mutations in UL54 DNA polymerase and UL97 kinase genes is problematic for the treatment of human cytomegalovirus (HCMV) diseases. During treatment of HCMV infection in a pediatric hematopoietic cell transplant recipie
Externí odkaz:
https://doaj.org/article/1bfd1d70b63c4f42add700203bf5597b
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging, tick-borne Bandavirus that causes lethal disease in humans. As there are no licensed vaccines and therapeutics for SFTSV, there is an urgent need to develop countermeasures aga
Externí odkaz:
https://doaj.org/article/9c032f05f6214ea89a9c20197e69da1b
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Sterile alpha motif (SAM) and histidine-aspartate (HD) domain-containing protein 1 (SAMHD1) acts as a restriction factor for several RNA and DNA viruses by limiting the intracellular pool of deoxynucleoside triphosphates. Here, we investigated the re
Externí odkaz:
https://doaj.org/article/2f5286001c9f4398a1a59159d2189233
Autor:
Subramaniyam Ravichandran, Young-Eui Kim, Varun Bansal, Ambarnil Ghosh, Jeonghwan Hur, Vinod Kumar Subramani, Subhra Pradhan, Myoung Kyu Lee, Kyeong Kyu Kim, Jin-Hyun Ahn
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007334 (2018)
G-quadruplex (G4), formed by repetitive guanosine-rich sequences, is known to play various key regulatory roles in cells. Herpesviruses containing a large double-stranded DNA genome show relatively higher density of G4-forming sequences in their geno
Externí odkaz:
https://doaj.org/article/0b63aa024835454097eb0e788482643d
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/02ba439d95d34fbcacc8eb7c4699641d
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Stimulator of interferon genes (STING) is a critical signaling molecule in the innate immune response against DNA viruses by either directly sensing intracellular DNA or functioning as an adaptor molecule to activate the type I interferon (IFN) signa
Externí odkaz:
https://doaj.org/article/42dca0e8c2c0443a9bb78a655f24508e
Autor:
Ye Ji Kim, Eui Tae Kim, Young-Eui Kim, Myoung Kyu Lee, Ki Mun Kwon, Keun Il Kim, Thomas Stamminger, Jin-Hyun Ahn
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005850 (2016)
Interferon-stimulated gene 15 (ISG15) encodes an ubiquitin-like protein that covalently conjugates protein. Protein modification by ISG15 (ISGylation) is known to inhibit the replication of many viruses. However, studies on the viral targets and vira
Externí odkaz:
https://doaj.org/article/71c0100d7306480086f55f80d6cddf7e
Autor:
Young-Eui Kim, Jin-Hyun Ahn
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004785 (2015)
Promyelocytic leukemia protein (PML), a major component of PML nuclear bodies (also known as nuclear domain 10), is involved in diverse cellular processes such as cell proliferation, apoptosis, gene regulation, and DNA damage response. PML also acts
Externí odkaz:
https://doaj.org/article/b96594b0b81d43fb9089aaf77557f4eb
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103308 (2014)
Post-translational modification of proteins by members of the small ubiquitin-like modifier (SUMO) is involved in diverse cellular functions. Many viral proteins are SUMO targets and also interact with the cellular SUMOylation system. During human cy
Externí odkaz:
https://doaj.org/article/d8d4630b48e44da68cfc4aa04a20d250