Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Young-Chul Youn"'
Autor:
Jung-Min Pyun, Young Ho Park, Young Chul Youn, Min Ju Kang, Kyu Hwan Shim, Jae-Won Jang, Jihwan You, Kwangsik Nho, SangYun Kim, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Various plasma biomarkers for amyloid-β (Aβ) have shown high predictability of amyloid PET positivity. However, the characteristics of discordance between amyloid PET and plasma Aβ42/40 positivity are poorly understood. Thorough interpret
Externí odkaz:
https://doaj.org/article/c4261899c6e84d078775daff928aa6fa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Developing reliable biomarkers is important for screening Alzheimer’s disease (AD) and monitoring its progression. Although EEG is non-invasive direct measurement of brain neural activity and has potentials for various neurologic disorders
Externí odkaz:
https://doaj.org/article/5942928ac74f470ebf573b9945920c49
Publikováno v:
Annals of Laboratory Medicine; Nov2024, Vol. 44 Issue 6, p576-580, 5p
Autor:
Cindy W. Yoon, Jonguk Kim, Young Ju Suh, Byeong C. Kim, Young Chul Youn, Jee Hyang Jeong, Hyun Jeong Han, Seong Hye Choi
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Background and purposeThe angiotensin-converting enzyme (ACE) insertion (I)/deletion (D) polymorphism has been studied as a genetic candidate for cerebral small vessel disease (CSVD). However, no previous study has evaluated the relationship between
Externí odkaz:
https://doaj.org/article/e7181e1d6b7a427292cfcef87b4a7263
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background Alpha-synuclein (α-syn) is considered the main pathophysiological protein component of Lewy bodies in synucleinopathies. α-Syn is an intrinsically disordered protein (IDP), and several types of structural conformations have been
Externí odkaz:
https://doaj.org/article/82e825e7a4214c8bb76614c73fd98399
Autor:
Young Chul Youn, Hye Ryoun Kim, Hae-Won Shin, Hae-Bong Jeong, Sang-Won Han, Jung-Min Pyun, Nayoung Ryoo, Young Ho Park, SangYun Kim
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background The tendency of amyloid-β to form oligomers in the blood as measured with Multimer Detection System-Oligomeric Amyloid-β (MDS-OAβ) is a valuable biomarker for Alzheimer’s disease and has been verified with heparin-based plasm
Externí odkaz:
https://doaj.org/article/2fe9a1f3d19646abb896e9de78160179
Publikováno v:
NeuroImage, Vol 272, Iss , Pp 120054- (2023)
For automatic EEG diagnosis, this paper presents a new EEG data set with well-organized clinical annotations called Chung-Ang University Hospital EEG (CAUEEG), which has event history, patient’s age, and corresponding diagnosis labels. We also desi
Externí odkaz:
https://doaj.org/article/83e69e1af6f94f3fbb9f9d52689812db
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
IntroductionThere has been significant development in blood-based biomarkers targeting amyloidopathy of Alzheimer's disease (AD). However, the guidelines for integrating such biomarkers into AD diagnosis are still inadequate. Multimer Detection Syste
Externí odkaz:
https://doaj.org/article/baaf5866e19947cabce550c6cee76d4b
Autor:
Cindy W. Yoon, Joung-Ho Rha, Hee-Kwon Park, Soo-Hyun Park, Soonwook Kwon, Byeong C. Kim, Young Chul Youn, Jee Hyang Jeong, Hyun Jeong Han, Seong Hye Choi
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Background and purposeSex differences in cerebral microbleeds (CMBs) are not well-known. We aimed to assess the impact of sex on the progression of CMBs.MethodsThe CHALLENGE (Comparison Study of Cilostazol and Aspirin on Changes in Volume of Cerebral
Externí odkaz:
https://doaj.org/article/c619dff09a2b4cb6b173a997b21151d5
Autor:
Rosha Babapour Mofrad, Philip Scheltens, SangYun Kim, Sungmin Kang, Young Chul Youn, Seong Soo A. An, Jori Tomassen, Bart N. M. van Berckel, Pieter Jelle Visser, Wiesje M. van der Flier, Charlotte E. Teunissen
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-10 (2021)
Abstract Objective We assessed the performance of plasma amyloid oligomerization tendency (OAβ) as a marker for abnormal amyloid status. Additionally, we examined long-term storage effects on plasma OAβ. Methods We included 399 subjects regardless
Externí odkaz:
https://doaj.org/article/b4d4b0f74e0c405c9f4317733a93b7c0