Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Young-Chan Kwon"'
Autor:
Gi Uk Jeong, Insu Hwang, Wooseong Lee, Ji Hyun Choi, Gun Young Yoon, Hae Soo Kim, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Seong-Jun Kim, Young-Chan Kwon, Kyun-Do Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 5, Pp 1221-1229 (2024)
Abstract Mouse models expressing human ACE2 for coronavirus disease 2019 have been frequently used to understand its pathogenesis and develop therapeutic strategies against SARS-CoV-2. Given that human TMPRSS2 supports viral entry, replication, and p
Externí odkaz:
https://doaj.org/article/0bfcda8eddce4df68827b69061b602d5
Autor:
Gi Uk Jeong, Hyung-Jun Kwon, Wern Hann Ng, Xiang Liu, Hyun Woo Moon, Gun Young Yoon, Hye Jin Shin, In-Chul Lee, Zheng Lung Ling, Alanna G. Spiteri, Nicholas J. C. King, Adam Taylor, Ji Soo Chae, Chonsaeng Kim, Dae-Gyun Ahn, Kyun-Do Kim, Young Bae Ryu, Seong-Jun Kim, Suresh Mahalingam, Young-Chan Kwon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
SARS-CoV-2 pathogenesis is very complex and not fully understood yet. Here, Jeong et al. show that intranasally infected K18-hACE2 transgenic mice develop ocular infection and retinal inflammation, while intratracheal infection results in the dissemi
Externí odkaz:
https://doaj.org/article/29d46674b74e4d01a917d241c0278701
Autor:
Sunhee Lee, Gun Young Yoon, Su Jin Lee, Young-Chan Kwon, Hyun Woo Moon, Yu-Jin Kim, Haesoo Kim, Wooseong Lee, Gi Uk Jeong, Chonsaeng Kim, Kyun-Do Kim, Seong-Jun Kim, Dae-Gyun Ahn
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Diverse severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have emerged since the beginning of the COVID-19 pandemic. We investigated the immunological and pathological peculiarity of the SARS-CoV-2 beta variant of concern
Externí odkaz:
https://doaj.org/article/a86bfb004a884aca872b9971584b98c2
Autor:
Gi Uk Jeong, Jaemyun Lyu, Kyun-Do Kim, Young Cheul Chung, Gun Young Yoon, Sumin Lee, Insu Hwang, Won-Ho Shin, Junsu Ko, June-Yong Lee, Young-Chan Kwon
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Accumulating evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes various neurological symptoms in patients with coronavirus disease 2019 (COVID-19). The most dominant immune cells in the brain
Externí odkaz:
https://doaj.org/article/5fbefd14f5c34d9f8602a26d9d514184
Autor:
Gi Uk Jeong, Gun Young Yoon, Hyun Woo Moon, Wooseong Lee, Insu Hwang, Haesoo Kim, Kyun-Do Kim, Chonsaeng Kim, Dae-Gyun Ahn, Bum-Tae Kim, Seong-Jun Kim, Young-Chan Kwon
Publikováno v:
Viruses, Vol 14, Iss 1, p 55 (2021)
SARS-CoV-2, like other RNA viruses, has a propensity for genetic evolution owing to the low fidelity of its viral polymerase. Several recent reports have described a series of novel SARS-CoV-2 variants. Some of these have been identified as variants
Externí odkaz:
https://doaj.org/article/a84874ec699549c78378a4bb9d7bb75b
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The novel coronavirus, SARS-CoV-2, or 2019-nCoV, which originated in Wuhan, Hubei province, China in December 2019, is a grave threat to public health worldwide. A total of 3,672,238 confirmed cases of coronavirus disease 2019 (COVID-19) and 254,045
Externí odkaz:
https://doaj.org/article/2961da5257714733809eb9951b5d2071
Autor:
Dae-Gyun Ahn, Gun Young Yoon, Sunhee Lee, Keun Bon Ku, Chonsaeng Kim, Kyun-Do Kim, Young-Chan Kwon, Geon-Woo Kim, Bum-Tae Kim, Seong-Jun Kim
Publikováno v:
Viruses, Vol 13, Iss 8, p 1639 (2021)
Recent outbreaks of zoonotic coronaviruses, such as Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have caused tremendous casualties and great economic shock. Although some re
Externí odkaz:
https://doaj.org/article/12e73baae23140f3899786fe6505d169
Autor:
Hye Jin Shin, Mi-Hwa Kim, Joo-Youn Lee, Insu Hwang, Gun Young Yoon, Hae Soo Kim, Young-Chan Kwon, Dae-Gyun Ahn, Kyun-Do Kim, Bum-Tae Kim, Seong-Jun Kim, Chonsaeng Kim
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 545 (2021)
Zika virus (ZIKV), which is associated with severe diseases in humans, has spread rapidly and globally since its emergence. ZIKV and dengue virus (DENV) are closely related, and antibody-dependent enhancement (ADE) of infection between cocirculating
Externí odkaz:
https://doaj.org/article/d44cc15bf6b346e6ade7382df74a53a1
Autor:
Byoung-Shik Shim, Young-Chan Kwon, Michael J. Ricciardi, Mars Stone, Yuka Otsuka, Fatma Berri, Jaclyn M. Kwal, Diogo M. Magnani, Cody B. Jackson, Audrey S. Richard, Philip Norris, Michael Busch, Christine L. Curry, Michael Farzan, David Watkins, Hyeryun Choe
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Preexisting immunity against dengue virus or West Nile virus was previously reported to mediate antibody-dependent enhancement (ADE) of Zika virus (ZIKV) infection in a mouse model. We show here that ZIKV-immune plasma samples from both symp
Externí odkaz:
https://doaj.org/article/a6218489bb8a42a58651197c773f907b
Autor:
Michael J Ricciardi, Diogo M Magnani, Alba Grifoni, Young-Chan Kwon, Martin J Gutman, Nathan D Grubaugh, Karthik Gangavarapu, Mark Sharkey, Cassia G T Silveira, Varian K Bailey, Núria Pedreño-Lopez, Lucas Gonzalez-Nieto, Helen S Maxwell, Aline Domingues, Mauricio A Martins, John Pham, Daniela Weiskopf, John Altman, Esper G Kallas, Kristian G Andersen, Mario Stevenson, Paola Lichtenberger, Hyeryun Choe, Stephen S Whitehead, Alessandro Sette, David I Watkins
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0006000 (2017)
Zika virus (ZIKV) is a mosquito-borne flavivirus of significant public health concern. In the summer of 2016, ZIKV was first detected in the contiguous United States. Here we present one of the first cases of a locally acquired ZIKV infection in a de
Externí odkaz:
https://doaj.org/article/e517563d855b415c83c79c2d54bdefb8