Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Young-Chae Chang"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5746 (2024)
4-O-Methyl-ascochlorin (MAC), a derivative of the prenyl–phenol antibiotic ascochlorin extracted from the fungus Ascochyta viciae, shows anticarcinogenic effects on various cancer cells. 5-Fluorouracil (5-FU) is used to treat colorectal cancer (CRC
Externí odkaz:
https://doaj.org/article/a01136acc77c41acb2b61b4ce9324278
Rg3-enriched red ginseng extract promotes lung cancer cell apoptosis and mitophagy by ROS production
Autor:
Soon-Kyung Hwang, Yun-Jeong Jeong, Hyun-Ji Cho, Yoon-Yub Park, Kwon-Ho Song, Young-Chae Chang
Publikováno v:
Journal of Ginseng Research, Vol 46, Iss 1, Pp 138-146 (2022)
Background: Red Ginseng has been used for many years to treat diseases. Ginsenoside Rg3 has documented therapeutic effects, including anticancer and anti-inflammatory activities. However, the anticancer effect of Rg3-enriched red ginseng extract (Rg3
Externí odkaz:
https://doaj.org/article/ab56aa5b466844eea86863ce64212c26
Autor:
Tak Gyeom Lee, Seon Min Woo, Seung Un Seo, Shin Kim, Jong-Wook Park, Young-Chae Chang, Taeg Kyu Kwon
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12816 (2023)
Ubiquitin-specific protease 2 (USP2) is a deubiquitinase belonging to the USPs subfamily. USP2 has been known to display various biological effects including tumorigenesis and inflammation. Therefore, we aimed to examine the sensitization effect of U
Externí odkaz:
https://doaj.org/article/389877ecce5c4414a035c988ebc02f06
Autor:
Seung Un Seo, Seon Min Woo, Seul Gi Lee, Min Yeong Kim, Hyun Shik Lee, Yung Hyun Choi, Sang Hyun Kim, Young-Chae Chang, Kyoung-jin Min, Taeg Kyu Kwon
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102336- (2022)
Cathepsin K inhibitor (odanacatib; ODN) and cathepsin K knockdown (siRNA) enhance oxaliplatin-induced apoptosis through p53-dependent Bax upregulation. However, its underlying mechanisms remain unclear. In this study, we elucidated the mechanism behi
Externí odkaz:
https://doaj.org/article/fc26d19e9df043848e42839342453da0
Autor:
Cheol Park, Jeong Sook Noh, Youngmi Jung, Sun-Hee Leem, Jin Won Hyun, Young-Chae Chang, Taeg Kyu Kwon, Gi-Young Kim, Hyesook Lee, Yung Hyun Choi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Fisetin is a kind of bioactive flavonol, widely present in various fruits such as strawberries and apples, and is known to act as a potent free radical scavenger. However, the mechanism of action related to the antioxidant activity of this compound i
Externí odkaz:
https://doaj.org/article/ea69b9974d6e4b7082e43e4f83e4474b
Autor:
Yuna Cho, Yun-Jeong Jeong, Kwon-Ho Song, Il-Kyung Chung, Junji Magae, Taeg Kyu Kwon, Yung-Hyun Choi, Jong-Young Kwak, Young-Chae Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15138 (2022)
4-O-methylascochlorin (MAC) is a 4-fourth carbon-substituted derivative of ascochlorin, a compound extracted from a phytopathogenic fungus Ascochyta viciae. MAC induces apoptosis and autophagy in various cancer cells, but the effects of MAC on apopto
Externí odkaz:
https://doaj.org/article/7b18c4a45c1947bf8534d12c6a7606f2
Autor:
Junyoung Park, Hyunju Choi, Fukushi Abekura, Hak‐Seong Lim, Jong‐Hwan Im, Woong‐Suk Yang, Cher‐Won Hwang, Young‐Chae Chang, Young-Choon Lee, Nam Gyu Park, Cheorl-Ho Kim
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In oat ingredients, flavonoids and phenolic acids are known to be the most important phenolic compounds. In phenolic compounds, wide-ranging biological responses, including antioxidative, anti-inflammatory, anti-allergic, and anti-cancer properties,
Externí odkaz:
https://doaj.org/article/28c31cd927e5401c81bdfa916749e928
Autor:
Hyesook Lee, Hyun Hwang-Bo, Seon Yeong Ji, Min Yeong Kim, So Young Kim, Minji Woo, Young-Sam Keum, Jeong Sook Noh, Joung-Hyun Park, Bae-Jin Lee, Gi-Young Kim, Eui Kyun Park, Young-Chae Chang, You-Jin Jeon, Yung Hyun Choi
Publikováno v:
Integrative Medicine Research, Vol 9, Iss 4, Pp - (2020)
Background: Oysters (Crassostrea gigas) are a popular marine product worldwide and have the advantage of nutritional benefits. This study aimed to investigate the effect of fermented oyster extract (FO) on growth promotion, including analysis of body
Externí odkaz:
https://doaj.org/article/0952626d9da64607aa924fe1807a92ca
Autor:
Xian Li, Youn Ju Lee, Fansi Jin, Young Na Park, Yifeng Deng, Youra Kang, Ju Hye Yang, Jae-Hoon Chang, Dong-Young Kim, Jung-Ae Kim, Young-Chae Chang, Hyun-Jeong Ko, Cheorl-Ho Kim, Makoto Murakami, Hyeun Wook Chang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Sirt1, a key regulator of metabolism and longevity, has recently been implicated in the regulation of allergic reactions, although the underlying mechanism remains unclear. Here we show that Sirt1 negatively regulates FcεRI-stimulated mast
Externí odkaz:
https://doaj.org/article/fe97cadf8a3945a097993ecc828d856a
Autor:
Junyoung Park, Sun-Hyung Ha, Fukushi Abekura, Hakseong Lim, Juni Magae, Ki-Tae Ha, Tae-Wook Chung, Young-Chae Chang, Young-Choon Lee, Eunyong Chung, Jiyeon Ku, Cheorl-Ho Kim
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Toll-like receptor 4 (TLR4) and matrix metalloproteinase-9 (MMP-9) are known to play important roles in inflammatory diseases such as arteriosclerosis and plaque instability. The purpose of this study was to perform the effect of 4-O-carboxymethylasc
Externí odkaz:
https://doaj.org/article/1a4376c889dc4fdea87ebb9f88650be2