Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Young V. Kwon"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102946- (2024)
Summary: Drosophila intestinal tumors show an extended cellular heterogeneity. We devise a protocol to assess tumor cell heterogeneity by employing nuclear size measurement and immunofluorescence-based cell lineage analysis. We describe steps for int
Externí odkaz:
https://doaj.org/article/d907e5305f0647838913ef6f00b62c70
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113245- (2023)
Summary: Many tumors recapitulate the developmental and differentiation program of their tissue of origin, a basis for tumor cell heterogeneity. Although stem-cell-like tumor cells are well studied, the roles of tumor cells undergoing differentiation
Externí odkaz:
https://doaj.org/article/625447109f06449b99878ea1feb7ea07
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Drosophila tumours can be utilised to study the mechanisms of cell dissemination. Here, the authors use Drosophila midgut to examine the course of Ras V12 -transformed cell dissemination from midgut into circulation, which requires the actions of inv
Externí odkaz:
https://doaj.org/article/5428b3c1740048ef835e5ad85a78ef01
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6249 (2021)
Sepsis is characterized by multiple-organ dysfunction caused by the dysregulated host response to infection. Until now, however, the role of the Wnt signaling has not been fully characterized in multiple organs during sepsis. This study assessed the
Externí odkaz:
https://doaj.org/article/6091d626b4d44c07820ab18b8aa8309a
Publikováno v:
Molecular Biology of the Cell. 34
Our study elucidates the role of E-cadherin (E-cad) in cell invasion during dissemination of transformed cells from the intestine. E-cad is a new component of invasive protrusions resembling invadopodia observed in cancer cells. Notably, E-cad contro
Autor:
Inae Sim, Jaewoong Jang, Jaewon Song, Jongkyu Lee, Hyemi Lim, Hyun Jung Lee, Gyusik Hwang, Young V. Kwon, Doheon Lee, Yoosik Yoon
Publikováno v:
Journal of Ethnopharmacology. 289:115079
Paeonia lactiflora Pall. is an ethnopharmacological medicine with a long history of human use for treating various inflammatory diseases in many Asian countries.Duchenne muscular dystrophy (DMD) is an X-linked degenerative muscle disease affecting 1
Autor:
Young V, Kwon, Bingqing, Zhao, Chiwei, Xu, Jiae, Lee, Chiao-Lin, Chen, Arunachalam, Vinayagam, Bruce A, Edgar, Norbert, Perrimon
Publikováno v:
Proc Natl Acad Sci U S A
Translationally controlled tumor protein (TCTP) is a highly conserved protein functioning in multiple cellular processes, ranging from growth to immune responses. To explore the role of TCTP in tissue maintenance and regeneration, we employed the adu
Autor:
Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam
Publikováno v:
eLife, Vol 12 (2024)
The α-arrestins form a large family of evolutionally conserved modulators that control diverse signaling pathways, including both G-protein-coupled receptor (GPCR)-mediated and non-GPCR-mediated pathways, across eukaryotes. However, unlike β-arrest
Externí odkaz:
https://doaj.org/article/26a1255e38244e79aa6faf01633eb0e2