Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Young Tang"'
Autor:
Shiyao Han, Yiyu Zhao, Fangyuan Mou, Zhen Yang, Ningxiao Li, Mengqi Cheng, Heshaungyi Xie, Baofu Qin, Young Tang
Publikováno v:
Bioengineering, Vol 11, Iss 11, p 1098 (2024)
Diosgenin (DSG) is a phytosterol saponin mainly found in Dioscorea zingiberensis C.H. Wright. It has shown promising results in treating various diseases such as cancer, diabetes, arthritis, asthma, and cardiovascular diseases. Diosgenin is also an i
Externí odkaz:
https://doaj.org/article/b3402e7b37e348ab87961f84fa555bc7
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
The coronavirus disease 2019 pandemic has caused over million death and 500 million reported cases globally. More effective antiviral medications are needed to curb the continued spread of this disease. The infection by SARS-CoV-2 virus is initiated
Externí odkaz:
https://doaj.org/article/27f966b9e61346c58fc330ecae40ef4a
Autor:
Chang Huang, Denzil Bernard, Jiaqi Zhu, Radha Charan Dash, Alexander Chu, Alec Knupp, Anna Hakey, M. Kyle Hadden, Antonio Garmendia, Young Tang
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically devastating diseases affecting the pork industry globally. PRRS is caused by PRRS virus (PRRSV). Currently there are no effective treatments agai
Externí odkaz:
https://doaj.org/article/5f2b1d07a8464d7e92b4f6890e5b49e4
Publikováno v:
Biology Open, Vol 8, Iss 12 (2019)
Human cell reprogramming remains extremely inefficient and the underlying mechanisms by different reprogramming factors are elusive. We found that NANOG and LIN28 (NL) synergize to improve OCT4, SOX2, KLF4 and MYC (OSKM)-mediated reprogramming by ∼
Externí odkaz:
https://doaj.org/article/ec32544efc6041bfbbd18dd64f5c1309
Autor:
Ling Wang, Zongliang Jiang, Delun Huang, Jingyue Duan, Chang Huang, Shannon Sullivan, Kaneha Vali, Yexuan Yin, Ming Zhang, Jill Wegrzyn, Xiuchun ( Cindy) Tian, Young Tang
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background The generation of induced pluripotent stem cells (iPSCs) has underdefined mechanisms. In addition, leukemia inhibitory factor (LIF) activated Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway is t
Externí odkaz:
https://doaj.org/article/1ab3031e31694fb7a4ff72bc39cdbd57
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 88-97 (2017)
The development of human induced pluripotent stem cells (iPSCs) holds great promise for regenerative medicine. However the iPSC induction efficiency is still very low and with lengthy reprogramming process. We utilized the highly potent transactivati
Externí odkaz:
https://doaj.org/article/3aa540e1de9843c19a33f02a1c2ecc84
Autor:
Ling Wang, Delun Huang, Zongliang Jiang, Yan Luo, Carol Norris, Ming Zhang, Xiuchun Tian, Young Tang
Publikováno v:
Biology Open, Vol 6, Iss 6, Pp 850-861 (2017)
The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt) pathway plays an important role in regulating cell proliferation, metabolism, and survival. However, the distinct roles of Akt isoforms (Akt1, Akt2, and Akt3) in pluripotent stem cel
Externí odkaz:
https://doaj.org/article/639fae16c44042cf9898c07f14e63a12
Autor:
Delun Huang, Ling Wang, Jingyue Duan, Chang Huang, Xiuchun (Cindy) Tian, Ming Zhang, Young Tang
Publikováno v:
Biology Open, Vol 7, Iss 1 (2018)
The regulatory process of naïve-state induced pluripotent stem cell (iPSC) generation is not well understood. Leukemia inhibitory factor (LIF)-activated Janus kinase/signal transducer and activator of transcription 3 (Jak/Stat3) is the master regula
Externí odkaz:
https://doaj.org/article/1ea4115ea2044d7f8680d9eb41f5bb98
Autor:
Delun Huang, Ling Wang, Neil C Talbot, Chang Huang, Liping Pu, Xiuling Zhao, Xiuchun Tian, Ming Zhang, Young Tang
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0203923 (2018)
Green fluorescent protein (GFP) reporters controlled by the regulatory region of OCT4 and NANOG-two master regulators for pluripotency are widely used in studies of pluripotent stem cell establishment and embryo development. Alongside the challenge i
Externí odkaz:
https://doaj.org/article/64779395ecea4041a040300cc710b127
Autor:
Lise Mumporeze, Chantal Uwamahoro, Doris Uwamahoro, Aly Beeman, Destry Jensen, Oliver Young Tang, Enyonam Odoom, Spandana Jarmale, Stephanie C. Garbern, Catalina González Marqués, Andrew Stephen, Adam R. Aluisio
Publikováno v:
Trauma Care, Vol 4, Iss 1, Pp 1-9 (2023)
In high-income nations, gender has been associated with injury characteristics. This study evaluated injury epidemiology and care based on gender at the Centre Hospitalier Universitaire de Kigali in Rwanda. Patients presenting to the emergency depart
Externí odkaz:
https://doaj.org/article/c529c6083b9e4d0ea3bb46a31756fddc