Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Young Sup Yoon"'
Autor:
Soo-Been Jeon, Hyebin Koh, A-Reum Han, Jieun Kim, Sunghun Lee, Jae-Ho Lee, Seung-Soon Im, Young-sup Yoon, Jong-Hee Lee, Ji Yoon Lee
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Red blood cell (RBC) generation from human pluripotent stem cells (PSCs) offers potential for innovative cell therapy in regenerative medicine as well as developmental studies. Ex vivo erythropoiesis from PSCs is currently limited by the low
Externí odkaz:
https://doaj.org/article/2b0edcb017f7431d97ebf6e3c32a580e
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Treating patients with refractory acute myeloid leukemia (AML) remains challenging. Currently there is no effective treatment for refractory AML. Increasing evidence has demonstrated that refractory/relapsed AML is associated with leukemic blasts whi
Externí odkaz:
https://doaj.org/article/16133de605be4219a840abe5f4e965a1
Autor:
Shin-Jeong Lee, Cholomi Jung, Jee Eun Oh, Sangsung Kim, Sangho Lee, Ji Yoon Lee, Young-sup Yoon
Publikováno v:
Cells, Vol 12, Iss 11, p 1554 (2023)
Red blood cell (RBC) transfusion is a lifesaving medical procedure that can treat patients with anemia and hemoglobin disorders. However, the shortage of blood supply and risks of transfusion-transmitted infection and immune incompatibility present a
Externí odkaz:
https://doaj.org/article/ea7cc80b3f52447992d6e26ba1ad900c
Autor:
Seonggeon Cho, Young-Doug Sohn, Sangsung Kim, Augustine Rajakumar, Martina L. Badell, Neil Sidell, Young-sup Yoon
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Preeclampsia (PE) is a prevalent pregnancy disorder that leads to high maternal and fetal morbidity and mortality. While defective vascular development and angiogenesis in placenta are known as crucial pathological findings, its pathophysiol
Externí odkaz:
https://doaj.org/article/e2c02648246749118589b17baac795b3
Autor:
Jun Chen, Xixi Zhang, Reid Millican, Tyler Lynd, Manas Gangasani, Shubh Malhotra, Jennifer Sherwood, Patrick Taejoon Hwang, Younghye Cho, Brigitta C. Brott, Gangjian Qin, Hanjoong Jo, Young-sup Yoon, Ho-Wook Jun
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to cardiovascular disease accounting for the high mortality in the United States. For developing effective treatments for atherosclerosis, considerable efforts have bee
Externí odkaz:
https://doaj.org/article/81ef9724664643c39ed92ec2e85c3f52
Autor:
Byungjun Kang, Jisoo Shin, Hyun-Ji Park, Chanryeol Rhyou, Donyoung Kang, Shin-Jeong Lee, Young-sup Yoon, Seung-Woo Cho, Hyungsuk Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Engineering 3D tissues faces the challenge of adequate vascularisation for nutrient delivery and gas exchange deep inside the construct. Here the authors use surface acoustic waves to create an aligned array of blood vessels in a hyaluronic acid hydr
Externí odkaz:
https://doaj.org/article/4f3258e1bd7542258b9877907ceb4409
Publikováno v:
Nature Cardiovascular Research. 2:420-422
Autor:
Xixi Zhang, Jun Chen, Brigitta C. Brott, Peter G. Anderson, Patrick T.J. Hwang, Jennifer Sherwood, Gillian Huskin, Young-sup Yoon, Renu Virmani, Ho-Wook Jun
Publikováno v:
ACS Applied Materials & Interfaces. 14:51728-51743
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 11, p 148 (2021)
Human induced pluripotent stem cells (hiPSCs) hold great promise for cardiovascular regeneration following ischemic injury. Considerable effort has been made toward the development and optimization of methods to differentiate hiPSCs into vascular cel
Externí odkaz:
https://doaj.org/article/09ffb386a6834076a432c3504635c24b
Autor:
Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon
Publikováno v:
Circulation.
BACKGROUND: Shortly after birth, cardiomyocytes exit the cell cycle and cease proliferation. At present, the regulatory mechanisms for this loss of proliferative capacity are poorly understood. CBX7 (chromobox 7), a polycomb group (PcG) protein, regu