Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Young Sun Kang"'
Autor:
Cheol Ho Park, Soon Jun Hong, Sung Gyun Kim, Seok Joon Shin, Dong Ki Kim, Jung Pyo Lee, Sang Youb Han, Sangho Lee, Jong Chul Won, Young Sun Kang, Jongha Park, Byoung-Geun Han, Ki-Ryang Na, Kyu Yeon Hur, Yong-Jin Kim, Sungha Park, Tae-Hyun Yoo
Publikováno v:
Clinical Hypertension, Vol 30, Iss 1, Pp 1-12 (2024)
Abstract Background The target blood pressure (BP) value is unclear for diabetic kidney disease (DKD). Therefore, we aimed to evaluate the effect of strict BP control or ‘on treatment’ BP on clinical outcomes in patients with DKD. Methods A post-
Externí odkaz:
https://doaj.org/article/d7b39fb2cd0b4376848c803867a6c05c
Publikováno v:
Kidney & Blood Pressure Research, Vol 49, Iss 1, Pp 81-90 (2024)
Introduction: Sodium-glucose cotransporter 2 (SGLT2) inhibitors target SGLT2 in renal proximal tubules and promote glycosuria in type 2 diabetes mellitus in humans and animal models, resulting in reduced blood glucose levels. Although clinical trials
Externí odkaz:
https://doaj.org/article/0c74f7d139b74404a08bd234905a2bfc
Autor:
Jin Joo Cha, Boo Yeon Park, Sung Gi Yoon, Hye Jin Park, Ji Ae Yoo, Jung Yeon Ghee, Dae Ryong Cha, Jae Young Seong, Young Sun Kang
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 187-196 (2023)
ABSTRACTThe spexin-based GALR2 agonist (NS200) is a novel drug, which has shown antidepressant and anxiolytic action in a recent experimental study. In this study, we investigated the effects of NS200 on renal injury in an animal model of type 2 diab
Externí odkaz:
https://doaj.org/article/b3688d217e9346e4a944dfc9797c6973
Publikováno v:
Animal Cells and Systems, Vol 27, Iss 1, Pp 112-119 (2023)
ABSTRACTPuromycin treatment can cause glomerular injury to the kidney, leading to proteinuria. However, the pathogenesis of acute kidney injury and subsequent regeneration after puromycin administration in animal models remain unclear. In this work,
Externí odkaz:
https://doaj.org/article/b5214c4f71b1474aa4f132651da2c9c9
Autor:
Jihyun Yang, Bong Gyun Sun, Hyeon-Jin Min, Young-Bin Son, Tae Bum Kim, Jonghyun Lee, Se Won Oh, Myung-Gyu Kim, Won Yong Cho, Shin Young Ahn, Gang-Jee Ko, Young Joo Kwon, Jin Joo Cha, Young Sun Kang, Dae Ryong Cha, Sang-Kyung Jo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Obstructive uropathy is known to be associated with acute kidney injury (AKI). This study aimed to investigate the etiologies, clinical characteristics, consequences and also assess the impact of AKI on long-term outcomes. This multicenter,
Externí odkaz:
https://doaj.org/article/32b1e064bec5459eb71209ed32f53529
Publikováno v:
Kidney Research and Clinical Practice, Vol 40, Iss 1, Pp 69-76 (2021)
Background Imbalance of T helper (Th) 1/2 cells has been shown to contribute to the development of immunoglobulin A nephropathy (IgAN). To address the inconsistent results on the role of Th1/Th2 polarization, we evaluated the levels of Th1/Th2 cytoki
Externí odkaz:
https://doaj.org/article/919269d6ffd8465aaa3322b069e21e56
Publikováno v:
Life, Vol 13, Iss 4, p 963 (2023)
NADPH oxidase (NOX)-derived oxidative stress is an important factor in renal progression, with NOX4 being the predominant NOX in the kidney. Recently, Src homology 3 (SH3) domain-containing YSC84-like 1 (SH3YL1) was reported to be a regulator of NOX4
Externí odkaz:
https://doaj.org/article/89628234c9c84b79ad1015747bb9a7bc
Autor:
Sang Youb Han, Jung Yeon Ghee, Jin Joo Cha, Young Sun Kang, Han Seong Kim, Dae Young Hur, Dae Ryong Cha
Publikováno v:
Life, Vol 13, Iss 2, p 277 (2023)
V-set Ig domain-containing 4 (VSIG4) regulates an inflammatory response and is involved in various diseases. However, the role of VSIG4 in kidney diseases is still unclear. Here, we investigated VSIG4 expression in unilateral ureteral obstruction (UU
Externí odkaz:
https://doaj.org/article/c71e47eefc374b88aa4538cbdc518db4
Autor:
Sang Youb Han, Jung Yeon Ghee, Jin Joo Cha, Young Sun Kang, Dae Young Hur, Han Seong Kim, Dae Ryong Cha
Publikováno v:
Life, Vol 12, Iss 7, p 1031 (2022)
Fibrosis is the final common finding in patients with advanced diabetic kidney disease. V-set Ig domain containing 4 (VSIG4) is related to fibrosis in several diseases. It also contributes to fibrosis under high-glucose conditions in renal tubule cel
Externí odkaz:
https://doaj.org/article/a3c2a3a01cde48238c63ecfc612c0f01
Autor:
Jung-Yeon Yoo, Dae Ryong Cha, Borim Kim, Eun Jung An, Sae Rom Lee, Jin Joo Cha, Young Sun Kang, Jung Yeon Ghee, Jee Young Han, Yun Soo Bae
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108245- (2020)
Summary: Cytosolic proteins are required for regulation of NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (Nox) isozymes. Here we show that Src homology 3 (SH3) domain-containing YSC84-like 1 (SH3YL1), as a Nox4 cytosolic regulator, medi
Externí odkaz:
https://doaj.org/article/c4db8bbe17f14753bfe684222bc94359