Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Young S. Rho"'
Publikováno v:
Ethnicityhealth.
Racial disparities in care and outcome have been demonstrated for several cancers, but it is not clear that a similar discrepancy exists for pancreatic cancer. Furthermore, there are limited data describing the pancreatic cancer experience of Pacific
Publikováno v:
HPB : the official journal of the International Hepato Pancreato Biliary Association. 23(7)
Background Hepatocellular carcinoma (HCC) is one of the few cancers that can be diagnosed based on imaging findings alone. The factors associated with the decision to perform a biopsy and the clinical impact have not been previously studied. Methods
Publikováno v:
Bulletin of the Korean Chemical Society. 32:4171-4175
Bio-functionalized gold nanoparticles (AuNPs), which bio-specifically interact with biotin-(strept)avidin, were investigated in this study. AuNPs were functionalized with a synthetically-provided biotin-linked thiol (BLT), which was synthesized by am
Publikováno v:
Bulletin of the Korean Chemical Society. 31:69-74
The new idarubicin analogues (12 and 13) with a glucose or galactoseas as a glycone were synthesized from daunomycin (2). (+)-4-Demethoxydaunomycinone (6) obtained from reaction of 2 with AlCl 3 was converted to 4-trifluoromethanesulfonyl daunomycino
Publikováno v:
Bulletin of the Korean Chemical Society. 27:1359-1363
Novel anthracycline analogues 2-9 as potential anticancer agents were synthesized from daunomycin (1a) and doxorubicin (1b). Compounds 2, 6, and 7 were prepared by the nucleophilic displacement type esterification of a 14-bromodaunomycin (1c) with a
Autor:
Pyoung Won Suh, Hyesun Kim, Dong Jin Yoo, Young S. Rho, Jihyung Park, Hong-Sig Sin, Gyuil Kim
Publikováno v:
Synthetic Communications. 34:1703-1722
Regiospecific syntheses of idarubicinone coupled with D‐glucuronic acid are described. Cyclization of dimethoxybenzene with carboxylic acid derivatives in polyphosphoric acid (PPA) in one step afforded the naphthalenones 7, which were transformed t
Publikováno v:
Synthetic Communications. 34:3497-3511
The first synthesis of new doxorubicin and daunomycin analogs containing glucuronic acid moieties instead of daunosamine are described. The desired products, daunomycinone‐7‐D‐glucuronide (DM7G, 10) and doxorubicinone‐7‐D‐glucuronide (DX7
Publikováno v:
Bulletin of the Korean Chemical Society. 23:1315-1327
The model compounds, 8-methoxypsoralen-CH 2 O(CH 2 ) n -adenine (MOPCH 2 OCnAd, n=2, 3, 5, 6, 8, and 10) in which 5 position of 8-methoxypsoralen (8-MOP) is linked by various lengths of polymethylene bridge to N 9 of adenine.UV absorption spectra are
Autor:
Wan-Joong Kim, Young S. Rho, Dong Jin Yoo, Soon‐Ryang Chung, Gyuil Kim, Siho Park, Heun-Soo Kang
Publikováno v:
Synthetic Communications. 32:1961-1975
The new anthracycline analogues (2–10) as potential anticancer agents were synthesized from daunomycin (1a) and doxorubicin (1b). Compounds 2, 6, and 7 were prepared by the nucleophilic displacement type esterification of a 14-bromodaunomycin (1c)
Publikováno v:
ChemInform. 28