Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Young Ri Shim"'
Autor:
Hee-Hoon Kim, Young-Ri Shim, Ha Neul Kim, Keungmo Yang, Tom Ryu, Kyurae Kim, Sung Eun Choi, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Hyemi Shin, Jae Myoung Suh, Youngae Jung, Geum-Sook Hwang, Won Kim, Seok-Hwan Kim, Hyuk Soo Eun, Je Kyung Seong, Won-Il Jeong
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112636- (2023)
Summary: Obesity-mediated hypoxic stress underlies inflammation, including interferon (IFN)-γ production by natural killer (NK) cells in white adipose tissue. However, the effects of obesity on NK cell IFN-γ production remain obscure. Here, we show
Externí odkaz:
https://doaj.org/article/d0d7fa527d414e97b49ac647aa5bdc1a
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The continuous rise in the prevalence of nonalcoholic fatty liver disease (NAFLD) is emerging as a global health issue. Although the protective effects of N-acetylcysteine (NAC), an antioxidant, against various diseases have been report
Externí odkaz:
https://doaj.org/article/2f77c20a8b084a14b94147ef5caebad6
Autor:
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Tolulope Esther Falana, Jae-Kwang Yoo, So-Hee Ahn, Minhye Park, Hyangmi Seo, Chulhee Choi, Won-Il Jeong
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 636 (2023)
Activation of Kupffer cells (KCs) by gut-derived lipopolysaccharide (LPS) instigates nuclear factor-κB (NF-κB)-mediated inflammatory responses in alcohol-associated liver diseases (ALD). Here, we utilized a novel optogenetically engineered exosome
Externí odkaz:
https://doaj.org/article/bfa0bbfbf3c44aae8bfe20f78b1af6fb
Autor:
Myung-Ho Kim, Hee-Hoon Kim, Jong-Min Jeong, Young-Ri Shim, Jun-Hee Lee, Ye Eun Kim, Tom Ryu, Keungmo Yang, Kyu-Rae Kim, Byeong-Min Jeon, Sun Chang Kim, Jae-Kwang Jung, Jae-Kap Choi, Young-Sun Lee, Jin-Seok Byun, Won-Il Jeong
Publikováno v:
Journal of Ginseng Research, Vol 44, Iss 6, Pp 815-822 (2020)
Background: Recently, beneficial roles of ginsenoside F2 (GF2), a minor constituent of Panax ginseng, have been demonstrated in diverse inflammatory diseases. However, its roles in alcoholic liver inflammation and injury have not been clearly underst
Externí odkaz:
https://doaj.org/article/0722f267c7d34bc8b469e06aa6e49f05
Autor:
Young-Ri Shim, Won-Il Jeong
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 5, Pp 772-780 (2020)
Alcoholic liver disease: cross-talk with other organs Therapies preventing the distribution of damage-associated molecules from other organs to the liver could help tackle alcoholic liver disease (ALD). Over time, metabolites from excessive alcohol c
Externí odkaz:
https://doaj.org/article/179dbe7ec165487686cfaa54ae3aabef
Publikováno v:
Nutrients, Vol 15, Iss 3, p 721 (2023)
Although tremendous research has reported the protective effects of natural compounds in nonalcoholic fatty liver disease (NAFLD), there is still no approved drug. This study aimed to examine the efficacy of Panax ginseng in NAFLD in preclinical stud
Externí odkaz:
https://doaj.org/article/cdf42b1080b647afa099727432fe2dd4
Autor:
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Myung-Ho Kim, Giljae Lee, Hyun Ju You, Won-Mook Choi, Keungmo Yang, Tom Ryu, Kyurae Kim, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Hyuk Soo Eun, Seok-Hwan Kim, GwangPyo Ko, Jong-Eun Park, Bin Gao, Won Kim, Won-Il Jeong
Publikováno v:
Experimental & Molecular Medicine. 55:158-170
Chronic alcohol consumption often induces hepatic steatosis but rarely causes severe inflammation in Kupffer cells (KCs) despite the increased hepatic influx of lipopolysaccharide (LPS), suggesting the presence of a veiled tolerance mechanism. In add
Autor:
So Yeon Kim, Jong-Min Jeong, Soo Jin Kim, Wonhyo Seo, Myung-Ho Kim, Won-Mook Choi, Wonbeak Yoo, Jun-Hee Lee, Young-Ri Shim, Hyon-Seung Yi, Young-Sun Lee, Hyuk Soo Eun, Byung Seok Lee, Kwangsik Chun, Suk-Jo Kang, Sun Chang Kim, Bin Gao, George Kunos, Ho Min Kim, Won-Il Jeong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Reactive species of oxygen promote the development of hepatic steatosis. Here, Kim et al. demonstrate that palmitate stimulates macrophage infiltration and increases oxidative stress during steatosis by binding to the TLR4–MD2 complex, which result
Externí odkaz:
https://doaj.org/article/8bb1e950316b49bfbfc161b1e107780f
Autor:
Hee-Hoon Kim, Young-Ri Shim, Ha Neul Kim, Keungmo Yang, Tom Ryu, Kyurae Kim, Sung Eun Choi, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Jaeone Jung, Youngae Jung, Geum-Sook Hwang, Won Kim, Seok-Hwan Kim, Hyuk Soo Eun, Je Kyung Seong, Won-Il Jeong
Obesity-mediated hypoxic stress underlies inflammatory responses, including interferon (IFN)-γ production by natural killer (NK) cells in white adipose tissue. However, the effects of obesity on NK cell IFN-γ production remain obscure. We demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73a1710cdb82e19ebbc5918591ea630b
https://doi.org/10.21203/rs.3.rs-2008307/v1
https://doi.org/10.21203/rs.3.rs-2008307/v1
Autor:
Keungmo Yang, Jun Hee Lee, Sung Eun Choi, Hyuk Soo Eun, Tom Ryu, Hee Hoon Kim, Ye Eun Kim, Won Mook Choi, Won Kim, Kyurae Kim, Seok-Hwan Kim, Young Ri Shim, Myung Ho Kim, Won-Il Jeong
Publikováno v:
Hepatology (Baltimore, Md.)References. 74(4)
Background and aims The important roles of glutamate and metabotropic glutamate receptor 5 (mGluR5) in HSCs have recently been reported in various liver diseases; however, the mechanism linking the glutamine/glutamate metabolism and mGluR5 in liver f