Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Young Mok, Lee"'
Autor:
Lane H. Wilson, Jun‐Ho Cho, Ana Estrella, Joan A. Smyth, Rong Wu, Tayoot Chengsupanimit, Laurie M. Brown, David A. Weinstein, Young Mok Lee
Publikováno v:
Hepatology Communications, Vol 3, Iss 11, Pp 1544-1555 (2019)
Mutations in the liver glycogen phosphorylase (Pygl) gene are associated with the diagnosis of glycogen storage disease type VI (GSD‐VI). To understand the pathogenesis of GSD‐VI, we generated a mouse model with Pygl deficiency (Pygl−/−). Pyg
Externí odkaz:
https://doaj.org/article/eb094ee5286e491c88069ed9a8d697ac
Autor:
Changhwan Kim, M.D., Younhee Kim, Ph.D., Dong-Wook Yang, Ph.D., Chin Kook Rhee, M.D., Sung Kyoung Kim, M.D., Yong-Il Hwang, M.D., Yong Bum Park, M.D., Young Mok Lee, M.D., Seonglim Jin, M.D., Jinkyeong Park, M.D., Cho-Rom Hahm, M.D., Chang-Han Park, M.D., So Yeon Park, M.D., Cheol Kweon Jung, M.D., Yu-Il Kim, M.D., Sang Haak Lee, M.D., Hyoung Kyu Yoon, M.D., Jin Hwa Lee, M.D., Seong Yong Lim, M.D., Kwang Ha Yoo, M.D., Ph.D.
Publikováno v:
Tuberculosis and Respiratory Diseases, Vol 82, Iss 1, Pp 27-34 (2019)
Background Understanding the burden of disease is important to establish cost-effective treatment strategies and to allocate healthcare resources appropriately. However, little reliable information is available regarding the overall economic burden
Externí odkaz:
https://doaj.org/article/75c25e4cc3db4df99a0d0a362ecb4785
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 3, Iss C, Pp 28-32 (2015)
Glycogen storage disease type Ia (GSD-Ia), characterized by impaired glucose homeostasis and chronic risk of hepatocellular adenoma (HCA), is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC) activity. In a previous 70–90 week-
Externí odkaz:
https://doaj.org/article/b10683e2853e43429f27cfe25940acc7
Autor:
Roberta Resaz, Davide Cangelosi, Daniela Segalerba, Martina Morini, Paolo Uva, Maria Carla Bosco, Giuseppe Banderali, Ana Estrella, Corbinian Wanner, David A. Weinstein, Annalisa Sechi, Sabrina Paci, Daniela Melis, Maja Di Rocco, Young Mok Lee, Alessandra Eva
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 328, p 328 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 328
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 328
Glycogen storage disease type Ia (GSDIa) is an inherited metabolic disorder caused by mutations in the enzyme glucose-6-phosphatase-α (G6Pase-α). Affected individuals develop renal and liver complications, including the development of hepatocellula
Autor:
Charles J, Arends, Lane H, Wilson, Ana, Estrella, Oh Sung, Kwon, David A, Weinstein, Young Mok, Lee
Publikováno v:
International journal of molecular sciences. 23(17)
Glycogen storage disease type IX (GSD-IX) constitutes nearly a quarter of all GSDs. This ketotic form of GSD is caused by mutations in phosphorylase kinase (PhK), which is composed of four subunits (α, β, γ, δ). PhK is required for the activation
Publikováno v:
Journal of Inherited Metabolic Disease. 44:118-128
Glycogen storage disease type Ia (GSD-Ia) is an inherited metabolic disease caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC) which plays a critical role in blood glucose homeostasis by catalyzing the hydrolysis of glucose-6-phos
Publikováno v:
Biochem Biophys Res Commun
Hepatocellular adenoma/carcinoma (HCA/HCC) is a long-term complication of the metabolic disorder glycogen storage disease type Ia (GSD-Ia) deficient in glucose-6-phosphatase-α (G6PC or G6Pase-α). We have shown previously that hepatic G6Pase-α defi
Glycogen storage disease type Ib (GSD-Ib), characterized by impaired glucose homeostasis, neutropenia, and neutrophil dysfunction, is caused by a deficiency in glucose-6-phosphate transporter (G6PT). Neutropenia in GSD-Ib has been known to result fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e040f822cfd71a075548dc1eae21e1
https://doi.org/10.21203/rs.3.rs-1271259/v1
https://doi.org/10.21203/rs.3.rs-1271259/v1
Autor:
Monika Dambska, Laurie M. Brown, Young Mok Lee, Kirsten E. Coleman, Andrew Specht, Kathryn R Dahlberg, David A. Weinstein, Thomas J. Conlon, Ana M. Estrella
Publikováno v:
Journal of Inherited Metabolic Disease. 41:977-984
Viral mediated gene therapy has progressed after overcoming early failures, and gene therapy has now been approved for several conditions in Europe and the USA. Glycogen storage disease (GSD) type Ia, caused by a deficiency of glucose-6-phosphatase-
Autor:
Choongyong Kwag, Volker Hessel, Dong Young Lee, Sung Won Lee, Moonyong Lee, Young Mok Lee, Nguyen Van Duc Long
Publikováno v:
Chemical Engineering and Processing - Process Intensification. 168:108535
There is an urgent need to reduce the CO2 emissions from global shipping. This study developed efficient sea-based CO2 capture, CO2 compression and liquefaction for a 3000 kW diesel engine. Several mixed solvents, an intercooler and multiple feeds ar