Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Young Lag Cho"'
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1185 (2021)
Klebsiella pneumoniae is one of the important clinical organisms that causes various infectious diseases, including urinary tract infections, necrotizing pneumonia, and surgical wound infections. The increase in the incidence of multidrug-resistance
Externí odkaz:
https://doaj.org/article/3f4c7fc378ab4cfd96a0db84cb9bf042
Autor:
Roshan D'Souza, Naina A. Pinto, Nguyen Le Phuong, Paul G. Higgins, Thao Nguyen Vu, Jung-Hyun Byun, Young Lag Cho, Jong Rak Choi, Dongeun Yong
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Acinetobacter spp. have emerged as significant pathogens causing nosocomial infections. Treatment of these pathogens has become a major challenge to clinicians worldwide, due to their increasing tendency to antibiotic resistance. To address this, muc
Externí odkaz:
https://doaj.org/article/a16ef794a65d49cdbf938621ea64a617
Autor:
Le Phuong Nguyen, Chul Soon Park, Naina Adren Pinto, Hyunsook Lee, Hyun Soo Seo, Thao Nguyen Vu, Hung Mai, An H. T. Pham, Eris Jang, Young Lag Cho, Karrie Goglin, Kevin Nguyen, Richard White, Roshan D’Souza, Derrick E. Fouts, Dongeun Yong
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 370 (2021)
The siderophore–antibiotic conjugate LCB10-0200 (a.k.a. GT-1) has been developed to combat multidrug-resistant Gram-negative bacteria. In this study, the in vitro activity of LCB10-0200 and LCB10-0200/avibactam (AVI) has been investigated against c
Externí odkaz:
https://doaj.org/article/b5c8cfd7f93645d099d0861df476a11a
Autor:
Le Phuong Nguyen, Naina Adren Pinto, Thao Nguyen Vu, Hyunsook Lee, Young Lag Cho, Jung-Hyun Byun, Roshan D’Souza, Dongeun Yong
Publikováno v:
Antibiotics, Vol 9, Iss 5, p 267 (2020)
This study investigates GT-1 (also known as LCB10-0200), a novel-siderophore cephalosporin, inhibited multidrug-resistant (MDR) Gram-negative pathogen, via a Trojan horse strategy exploiting iron-uptake systems. We investigated GT-1 activity and the
Externí odkaz:
https://doaj.org/article/6ab51ae08215408eba2c71e51f695631
Autor:
Young Lag Cho, Jichan Jang
Publikováno v:
Applied Sciences, Vol 10, Iss 7, p 2211 (2020)
A novel oxazolidinone with cyclic amidrazone, delpazolid (LCB01-0371), was synthesized by LegoChem BioSciences, Inc. (Daejeon, Korea). Delpazolid can improve the minimum bactericidal concentration of Mycobacterium tuberculosis H37Rv and significantly
Externí odkaz:
https://doaj.org/article/9d0416edba744667960cca5eb07992e8
Autor:
Le Phuong Nguyen, Naina Adren Pinto, Thao Nguyen Vu, Hung Mai, An HT Pham, Hyunsook Lee, Young Lag Cho, Jung-Hyun Byun, Roshan D’Souza, Dongeun Yong
Publikováno v:
Pathogens, Vol 8, Iss 4, p 212 (2019)
Recently, a blaNDM-9 and mcr-1 co-harboring E. coli ST 617 isolate was identified from an asymptomatic carrier in Korea. An 81-year-old female was admitted to a university hospital for aortic cardiac valve repair surgery. Following surgery, she was a
Externí odkaz:
https://doaj.org/article/ad3f993aaace4e0692f9d009fe2bfffd
Publikováno v:
Antibiotics, Vol 10, Iss 1185, p 1185 (2021)
Antibiotics
Volume 10
Issue 10
Antibiotics
Volume 10
Issue 10
Klebsiella pneumoniae is one of the important clinical organisms that causes various infectious diseases, including urinary tract infections, necrotizing pneumonia, and surgical wound infections. The increase in the incidence of multidrug-resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c5119e7aa9c5e4c461b6d305b350a2
https://www.mdpi.com/2079-6382/10/10/1185
https://www.mdpi.com/2079-6382/10/10/1185
Autor:
Sang-Hun Oh, Hee-Soo Park, Jun-Hyung Lee, Sung-Yun Baek, Sang-Eun Chae, Kyuman Oh, Young Lag Cho, Jin-Hwan Kwak
Publikováno v:
Molecules, Vol 22, Iss 12, p 2096 (2017)
LCB01-0648 is a novel oxazolidinone compound that shows potent antibacterial activities against most Gram-positive cocci, including the multi-drug resistant Staphylococcus aureus. In this study, in vivo activity of LCB01-0699, a LCB01-0648 prodrug, a
Externí odkaz:
https://doaj.org/article/b938f5cfd90f49a79f773ed819c5d143
Autor:
Sang-Hun Oh, Josep Kim, Sung-Yoon Baek, Sang-Eun Chae, Hee-Soo Park, Young-Lag Cho, Jin-Hwan Kwak
Publikováno v:
Molecules, Vol 22, Iss 3, p 394 (2017)
Oxazolidinones are a novel class of synthetic antibacterial agents that inhibit bacterial protein synthesis. Here, we synthesized and tested a series of oxazolidinone compounds containing cyclic amidrazone. Among these compounds, we further investiga
Externí odkaz:
https://doaj.org/article/c0325a31ac484d03a38466944a346212
Autor:
Hyun-Sook Lee, Roshan D'Souza, Kevin Nguyen, Chul Soon Park, Hyun Soo Seo, Le Phuong Nguyen, Thao Nguyen Vu, Richard C. White, Dongeun Yong, Eris Jang, Young Lag Cho, Derrick E. Fouts, An H.T. Pham, Hung Mai, Naina Adren Pinto, Karrie Goglin
Publikováno v:
Pharmaceuticals
Volume 14
Issue 4
Pharmaceuticals, Vol 14, Iss 370, p 370 (2021)
Volume 14
Issue 4
Pharmaceuticals, Vol 14, Iss 370, p 370 (2021)
The siderophore–antibiotic conjugate LCB10-0200 (a.k.a. GT-1) has been developed to combat multidrug-resistant Gram-negative bacteria. In this study, the in vitro activity of LCB10-0200 and LCB10-0200/avibactam (AVI) has been investigated against c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a598f6880b601c54fe3bbe1728e4be5a
http://europepmc.org/articles/PMC8072773
http://europepmc.org/articles/PMC8072773