Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Young K, Chae"'
Publikováno v:
Heliyon, Vol 6, Iss 5, Pp e03841- (2020)
Background: Reversion mutations of somatic BRCA mutations are an important source of resistance within ovarian cancer. Furthermore, these reversion mutations are known to change over the course of treatment. Better understanding of the mechanisms lea
Externí odkaz:
https://doaj.org/article/b27777be51ee420083590ccb8e9feb47
Autor:
Sarki A. Abdulkadir, Francis J. Giles, Young K. Chae, Massimo Cristofanilli, Siraj M. Ali, Julia A. Elvin, Laurie Gay, Jeffrey S. Ross, Timothy M. Kuzel, Richard B. Lanman, Rebecca J. Nagy, Rubens B. Costa, Ximing J. Yang, HuiYing Han, Kenji Unno, Vinay Sagar, Ami N. Shah, Sahithi Pamarthy, Benedito A. Carneiro
Figure S1 ALK genomic alterations and mRNA expression in human cancers. Figure S2 Efficacy of ALK inhibitors in prostate cancer cell lines. Table S1 Summary of mutations and their percentages identified by ctDNA profiling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1a8d1b8fbbd18b54d0ed1b4de078e1
https://doi.org/10.1158/1078-0432.22474914.v1
https://doi.org/10.1158/1078-0432.22474914.v1
Autor:
Sarki A. Abdulkadir, Francis J. Giles, Young K. Chae, Massimo Cristofanilli, Siraj M. Ali, Julia A. Elvin, Laurie Gay, Jeffrey S. Ross, Timothy M. Kuzel, Richard B. Lanman, Rebecca J. Nagy, Rubens B. Costa, Ximing J. Yang, HuiYing Han, Kenji Unno, Vinay Sagar, Ami N. Shah, Sahithi Pamarthy, Benedito A. Carneiro
Purpose: Small cell carcinoma of the prostate (SCCP) is an aggressive disease that can arise de novo or by transdifferentiation from prostate adenocarcinoma. Alterations in anaplastic lymphoma kinase (ALK) gene are involved in neuroblastoma, lung can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5214bf1fbee91715c0ba541ca1ed4c
https://doi.org/10.1158/1078-0432.c.6528936
https://doi.org/10.1158/1078-0432.c.6528936
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Immune checkpoint inhibitors targeting the programmed cell death receptor 1 (PD-1) are increasingly used to treat several malignancies, with the most common adverse event being cutaneous toxicity. We report the case of a 68-years-old man with stage I
Externí odkaz:
https://doaj.org/article/bbd8b744ad2e499fb00a0622a958c20d
Autor:
Moataz A.S. Soliman, Linda C. Kelahan, Michael Magnetta, Hatice Savas, Rishi Agrawal, Ryan J. Avery, Pascale Aouad, Benjamin Liu, Yue Xue, Young K. Chae, Riad Salem, Al B. Benson, Vahid Yaghmai, Yuri S. Velichko
Publikováno v:
JCO Clinical Cancer Informatics.
PURPOSE Variability in computed tomography images intrinsic to individual scanners limits the application of radiomics in clinical and research settings. The development of reproducible and generalizable radiomics-based models to assess lesions requi
Autor:
Lorenzo Gerratana, Michael Movarek, Firas Wehbe, Neelima Katam, Devalingam Mahalingam, Jeannine Donahue, Ami Shah, Young K. Chae, Mary Mulcahy, Dean Tsarwhas, Victoria Villaflor, Aparna Kalyan, Maha Hussein, Jyoti Patel, Sunandana Chandra, Leonidas C. Platanias, William Gradishar, Massimo Cristofanilli, Amir Behdad
Publikováno v:
JCO precision oncology. 6
PURPOSE Circulating tumor DNA (ctDNA) has emerged as a promising noninvasive biomarker for baseline characterization and longitudinal monitoring of a tumor throughout disease management. The aim of this study was to evaluate the utility of ctDNA acro
Autor:
Benedito A, Carneiro, Sahithi, Pamarthy, Ami N, Shah, Vinay, Sagar, Kenji, Unno, HuiYing, Han, Ximing J, Yang, Rubens B, Costa, Rebecca J, Nagy, Richard B, Lanman, Timothy M, Kuzel, Jeffrey S, Ross, Laurie, Gay, Julia A, Elvin, Siraj M, Ali, Massimo, Cristofanilli, Young K, Chae, Francis J, Giles, Sarki A, Abdulkadir
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 24(12)
PURPOSE: Small cell carcinoma of the prostate (SCCP) is an aggressive disease that can arise de novo or by transdifferentiation from prostate adenocarcinoma. Alterations in anaplastic lymphoma kinase (ALK) gene are involved in neuroblastoma, lung can
Autor:
Sherilyn Alvaran Tuazon, Gentry Teng King, Joanna Sta. Cruz, Young K. Chae, Jean B. Ong Kian Koc, Sarah Hegarty, John Charles Leighton
Publikováno v:
Journal of Clinical Oncology. 32:e14516-e14516
Publikováno v:
Journal of Clinical Oncology. 30:40-40
40 Background: The Mevalonic Acid Pathway has been implicated in the promotion of a microenvironment suitable for establishment of bony metastasis from breast cancer. The statins, which act on this pathway, have been shown to have in vitro antineopla