Výsledky vyhledávání - "Young Jun Kang"

Akademický článek

Mitochondrial PGAM5−Drp1 signaling regulates the metabolic reprogramming of macrophages and regulates the induction of inflammatory responses

Autor: Bo-Ram Bang, Haruka Miki, Young Jun Kang

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Macrophages play a critical role in the regulation of inflammation and tissue homeostasis. In addition to their vital functions for cell survival and physiology, mitochondria play a crucial role in innate immunity as a platform for the induction of i

Externí odkaz: https://doaj.org/article/58e6cdf1de50471f98bce633037dc240

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Akademický článek

Mass Flow Function Correlation for Solid and Honeycomb Land Labyrinth Seals including Fin Front Angle, Clearance, Fin Number and Honeycomb Geometry

Autor: Hyeok Je Kim, Young Jun Kang, Woojun Kim, Ye Rim Jo, Suhyeon Park, Jae Su Kwak

Publikováno v: Machines, Vol 11, Iss 9, p 880 (2023)

In this study, the effects of several geometry factors (fin front angle, clearance, number of fins, and honeycomb cell diameter and depth) on the mass flow function of solid and honeycomb land were studied experimentally. The fin front angle consider

Externí odkaz: https://doaj.org/article/9567d74cacd14e8cbf99a16f88020a80

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Akademický článek

MicroRNA-22 Regulates the Pro-inflammatory Responses and M1 Polarization of Macrophages by Targeting GLUT1 and 4-1BBL

Autor: Young Jun Kang

Publikováno v: Journal of Immunology Research, Vol 2023 (2023)

Many microRNAs (miRNAs) are selectively expressed in mammalian immune cells and have been linked to immune responses in host defense and autoimmune disease. In macrophages, miRNAs regulate cell metabolism by repressing the expression of genes such as

Externí odkaz: https://doaj.org/article/577d08cdc2bc46fbb47d7a4db6bd62be

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Akademický článek

Unique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model.

Autor: Takeshi Yoshikawa, Motoyuki Otsuka, Takahiro Kishikawa, Akemi Takata, Motoko Ohno, Chikako Shibata, Young Jun Kang, Haruhiko Yoshida, Kazuhiko Koike

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e71969 (2013)

A widespread downregulated expression of microRNAs (miRNAs) is commonly observed in human cancers. Similarly, deregulated expression of miRNA-processing pathway components, which results in the reduction of global miRNA expression, may also be associ

Externí odkaz: https://doaj.org/article/0b60ac1bc3b44817ba49bb88dec6de94

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Akademický článek

Epithelial p38alpha controls immune cell recruitment in the colonic mucosa.

Autor: Young Jun Kang, Motoyuki Otsuka, Arjen van den Berg, Lixin Hong, Zhe Huang, Xiurong Wu, Duan-Wu Zhang, Bruce A Vallance, Peter S Tobias, Jiahuai Han

Publikováno v: PLoS Pathogens, Vol 6, Iss 6, p e1000934 (2010)

Intestinal epithelial cells (IECs) compose the first barrier against microorganisms in the gastrointestinal tract. Although the NF-kappaB pathway in IECs was recently shown to be essential for epithelial integrity and intestinal immune homeostasis, t

Externí odkaz: https://doaj.org/article/490526f1daf74d059290c0f4080e0328

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