Výsledky vyhledávání - "Young Jin Kang"

Akademický článek

Unraveling Connective Tissue Growth Factor as a Therapeutic Target and Assessing Kahweol as a Potential Drug Candidate in Triple-Negative Breast Cancer Treatment

Autor: Jeong Hee Lee, Jongsu Kim, Hong Sook Kim, Young Jin Kang

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 22, p 16307 (2023)

Triple-negative breast cancer (TNBC) is characterized by aggressive behavior and limited treatment options, necessitating the identification of novel therapeutic targets. In this study, we investigated the clinical significance of connective tissue g

Externí odkaz: https://doaj.org/article/94a9ecb0522240fa9154646258b9357b

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Akademický článek

Farrerol Induces Cancer Cell Death via ERK Activation in SKOV3 Cells and Attenuates TNF-α-Mediated Lipolysis

Autor: Jongbeom Chae, Jin Soo Kim, seok tae Choi, Seul Gi Lee, Oyindamola Vivian Ojulari, Young Jin Kang, Taeg Kyu Kwon, Ju-Ock Nam

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 17, p 9400 (2021)

Farrerol (FA) is a flavanone isolated from the Chinese herbal medicine “Man-shan-hong” (Rhododendron dauricum L.). In the present study, FA decreased the viability of SKOV3 cells in a dose- and time-dependent manner, and it induced G2/M cell cycl

Externí odkaz: https://doaj.org/article/8793b7243746406795724a9852ea1d5c

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Akademický článek

Kahweol, a Diterpenoid Molecule, Inhibits CTGF-Dependent Synthetic Phenotype Switching and Migration in Vascular Smooth Muscle Cells

Autor: Jeong Hee Lee, Seok Tae Choi, Young Jin Kang

Publikováno v: Molecules, Vol 26, Iss 3, p 640 (2021)

Vascular smooth muscle cell (VSMC) phenotype switching from contractile to synthetic is essential for proliferation and migration in vascular pathophysiology. Connective tissue growth factor (CTGF) is a matricellular protein involved in cell adhesion

Externí odkaz: https://doaj.org/article/e19e8ec8f98645a7b40b6375163f5f22

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Akademický článek

Hastelloy C276/AISI SS304 dissimilar metal welding: A comparative review of the effective application of laser and Micro-GTAW

Autor: Byeong-heon Kim, Ki-hwan Kim, Young-jin Kang, Sung-shin Kim, Hee-je Kim

Publikováno v: Journal of Materials Research and Technology, Vol 32, Iss , Pp 621-633 (2024)

Hastelloy C276, known for its high temperature strength and corrosion resistance, is essential in the manufacture of medical devices and aerospace components. This study developed a micro-controlled GTA welding technology capable of precisely welding

Externí odkaz: https://doaj.org/article/b8b6c8daace945e9b8f1707ffc2c2a41

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Akademický článek

Fluvastatin inhibits AGE-induced cell proliferation and migration via an ERK5-dependent Nrf2 pathway in vascular smooth muscle cells.

Autor: Ae-Rang Hwang, Jung-Hwa Han, Jae Hyang Lim, Young Jin Kang, Chang-Hoon Woo

Publikováno v: PLoS ONE, Vol 12, Iss 5, p e0178278 (2017)

Advanced glycation endproduct (AGE)-induced vascular smooth muscle cell (VSMC) proliferation and reactive oxygen species (ROS) production are emerging as important mechanisms of diabetic vasculopathy, but little is known about the molecular mechanism

Externí odkaz: https://doaj.org/article/8ea970796b984ee28595c0996a84cb6a

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Akademický článek

Cross-Method-Based Analysis and Classification of Malicious Behavior by API Calls Extraction

Autor: Bruce Ndibanje, Ki Hwan Kim, Young Jin Kang, Hyun Ho Kim, Tae Yong Kim, Hoon Jae Lee

Publikováno v: Applied Sciences, Vol 9, Iss 2, p 239 (2019)

Data-driven public security networking and computer systems are always under threat from malicious codes known as malware; therefore, a large amount of research and development is taking place to find effective countermeasures. These countermeasures

Externí odkaz: https://doaj.org/article/617dc9ef87e64461873a09ae053dc0c6

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Akademický článek

AMP-Activated Protein Kinase Activation by 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) Inhibits Palmitate-Induced Endothelial Cell Apoptosis Through Reactive Oxygen Species Suppression

Autor: Ji-Eun Kim, Yong-Woon Kim, In Kyu Lee, Jong-Yeon Kim, Young Jin Kang, So-Young Park

Publikováno v: Journal of Pharmacological Sciences, Vol 106, Iss 3, Pp 394-403 (2008)

AMP-activated protein kinase (AMPK) activation has an antiapoptotic effect in endothelial cells, but the mechanisms involved remain unclear. Here, we investigated whether AMPK activation could inhibit palmitate-induced apoptosis through suppression o

Externí odkaz: https://doaj.org/article/7c4419d1fba84c5cb9f2380a69a7c5d5

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