Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Young Hyun, Yoo"'
Autor:
Hye Young Kim, Young Hyun Yoo
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2082 (2022)
Nonalcoholic fatty liver disease (NAFLD) is a major health issue. NAFLD can progress from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH). NASH can progress to cirrhosis or hepatocellular carcinoma. Unfortunately, there is no currentl
Externí odkaz:
https://doaj.org/article/7ef9333411fe4e45ba7c574a3a90645d
Autor:
Young Hyun Yoo, Sung-Heun Kim, Do-Young Kang, Wol Soon Jo, Young Hwa Soung, Na Young Jeong, Jee Hyun Rho, Sang Yull Lee, Tae-Hyun Kim
In the present study, we identified a missense mutation (G199V) in KAT-18 cell line established from primary cultures of anaplastic thyroid cancer (ATC). Notably, knockdown of this mutant (mt) p53 reduced cell viability and exerted antitumor activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22521456479a079e98166c7ed8ed31b5
https://doi.org/10.1158/1541-7786.c.6542670
https://doi.org/10.1158/1541-7786.c.6542670
Autor:
Young Hyun Yoo, Sung-Heun Kim, Do-Young Kang, Wol Soon Jo, Young Hwa Soung, Na Young Jeong, Jee Hyun Rho, Sang Yull Lee, Tae-Hyun Kim
Supplementary Data from Mutant p53 (G199V) Gains Antiapoptotic Function through Signal Transducer and Activator of Transcription 3 in Anaplastic Thyroid Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c432230b27319ba768346ae5e39dcdf
https://doi.org/10.1158/1541-7786.22520529
https://doi.org/10.1158/1541-7786.22520529
Autor:
Ji Sook Kang, Il-Whan Choi, Min Ho Han, Dae-Sung Lee, Gi-Young Kim, Hye Jin Hwang, Byung Woo Kim, Cheol Min Kim, Young Hyun Yoo, Yung Hyun Choi
Publikováno v:
Marine Drugs, Vol 13, Iss 5, Pp 2666-2679 (2015)
This study was designed to examine the protective effects of the marine brown algae Petalonia binghamiae against oxidative stress-induced cellular damage and to elucidate the underlying mechanisms. P. binghamiae methanol extract (PBME) prevented hydr
Externí odkaz:
https://doaj.org/article/8ad37bb6ffcb40ce8b692a1046a85cc1
Autor:
Yoon-Jae Kim, Ji-Eun Park, Jin-Yong Chung, Ji Young Kim, Seung Gee Lee, Seung-Jin Lee, Wook-Joon Yu, Hye Young Kim, Hyeon Jun Kim, Hyungjong Koh, Hae-Rahn Bae, Young Hyun Yoo, Jong-Min Kim
Publikováno v:
The Journal of toxicological sciences. 47(8)
Testicular Leydig cells produce testosterone through the participation of steroidogenic proteins. The CYP1B1 enzyme has been shown to catalyze 7,12-dimethylbenzanthracene (DMBA), a representative polycyclic aromatic hydrocarbon. We hypothesized that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f61039a42dbd679c7b473fe5deb0e7a
https://pubmed.ncbi.nlm.nih.gov/35908932
https://pubmed.ncbi.nlm.nih.gov/35908932
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 5981-5998 (2014)
Although fucoidan has been shown to exert anticancer activity against several types of cancer cell lines, no reports have explored fucoidan-affected cell growth in human urinary bladder cancer cells. In this study, we investigated the anti-proliferat
Externí odkaz:
https://doaj.org/article/8dd16e535fb44eb289bf96bf488f8a8b
Autor:
Yung Hyun Choi, Young Hyun Yoo, Nam Deuk Kim, Wun-Jae Kim, Gi-Young Kim, Hee-Jae Cha, Hyun Soo Park, Hye Jin Hwang
Publikováno v:
Marine Drugs, Vol 11, Iss 7, Pp 2347-2364 (2013)
The present study investigated possible mechanisms on the apoptosis induction of human leukemic cells by fucoidan, a sulfated polysaccharide found in marine algae. Fucoidan treatment of cells resulted in inhibition of growth and induction of apoptosi
Externí odkaz:
https://doaj.org/article/9663e2907aef49abb685dbfc68c9a7b0
Autor:
Sung Won Lee, Jee Hyun Rho, Sang Yeob Lee, Seung Hee Yoo, Hye Young Kim, Won Tae Chung, Young Hyun Yoo
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166450 (2016)
Although alpha (α)B-crystallin is expressed in articular chondrocytes, little is known about its role in these cells. Protein kinase casein kinase 2 (CK2) inhibition induces articular chondrocyte death. The present study examines whether αB-crystal
Externí odkaz:
https://doaj.org/article/e78128791e9e45cca7278eed5593e9aa
Publikováno v:
Developmentreproduction. 26(2)
In response to luteinizing hormone (LH), a higher concentration of progesterone (P4) is produced in luteal cells of corpus luteum (CL). Mitochondria are an essential cellular organelle in steroidogenesis. The specific engagement of the concept regard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a45156cd8907c21bbee3f8b18e7c0a3
https://pubmed.ncbi.nlm.nih.gov/35950164
https://pubmed.ncbi.nlm.nih.gov/35950164
Autor:
Hyun-Seok Jin, Jeonghyun Kim, Sangwook Park, Eunkuk Park, Bo-Young Kim, Vit-Na Choi, Young-Hyun Yoo, Bom-Taeck Kim, Seon-Yong Jeong
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135285 (2015)
To identify novel susceptibility variants for osteoporosis in Korean postmenopausal women, we performed a genome-wide association analysis of 1180 nonsynonymous single nucleotide polymorphisms (nsSNPs) in 405 individuals with osteoporosis and 722 nor
Externí odkaz:
https://doaj.org/article/5649eb2f2ac345ad85cbc6b67b9a0543