Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Young Hye You"'
Autor:
Heon‐Seok Park, Eun Young Lee, Young‐Hye You, Marie Rhee, Jong‐Min Kim, Seong‐Soo Hwang, Poong‐Yeon Lee
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 6, Pp 693-703 (2024)
Abstract Aims/Introduction To investigate the long‐term efficacy of various encapsulated xenogeneic islet transplantation, and to explore the impact of different donor porcine genetic traits on islet transplantation outcomes. Materials and Methods
Externí odkaz:
https://doaj.org/article/499d326e5c65415ca42dfb26bbf9fabf
Autor:
Gyeong-Jin Cheon, Heon-Seok Park, Eun-Young Lee, Min Jung Kim, Young-Hye You, Marie Rhee, Ji-Won Kim, Kun-Ho Yoon
Publikováno v:
Diabetes & Metabolism Journal, Vol 46, Iss 5, Pp 677-688 (2022)
Background Neonatal porcine pancreatic cell clusters (NPCCs) have been proposed as an alternative source of β cells for islet transplantation because of their low cost and growth potential after transplantation. However, the delayed glucose lowering
Externí odkaz:
https://doaj.org/article/541cf1289cc54f4ea3f60e3480cbe48c
Autor:
Min Jung Kim, Heon-Seok Park, Ji-Won Kim, Eun-Young Lee, Marie Rhee, Young-Hye You, Gilson Khang, Chung-Gyu Park, Kun-Ho Yoon
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 1, Pp 146-156 (2021)
Background The microencapsulation is an ideal solution to overcome immune rejection without immunosuppressive treatment. Poor biocompatibility and small molecular antigens secreted from encapsulated islets induce fibrosis infiltration. Therefore, the
Externí odkaz:
https://doaj.org/article/b7a945e27f944d35bcecdca1a8ac99eb
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101958- (2020)
For alternative sources of β cells, patient-specific induced pluripotent stem cells (iPSCs) could be promising, as cells derived from the “self” allow autologous transplantation. However, only a few studies have investigated insulin-producing ce
Externí odkaz:
https://doaj.org/article/26b97ff8aec147e9ba28e8538363c9ab
Autor:
Marie Rhee, Gilson Khang, Kun Ho Yoon, Heon Seok Park, Young Hye You, Chung Gyu Park, Min Jung Kim, Eun Young Lee, Ji-Won Kim
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 1, Pp 146-156 (2021)
Endocrinology and Metabolism
Endocrinology and Metabolism
Background: The microencapsulation is an ideal solution to overcome immune rejection without immunosuppressive treatment. Poor biocompatibility and small molecular antigens secreted from encapsulated islets induce fibrosis infiltration. Therefore, th
Autor:
Jin-Sun Chang, Young-Hye You, Shin-Young Park, Ji-Won Kim, Hun-Sung Kim, Kun-Ho Yoon, Jae-Hyoung Cho
Publikováno v:
Diabetes & Metabolism Journal, Vol 37, Iss 6, Pp 475-483 (2013)
BackgroundWe aimed to quantify stress-induced hyperglycemia and differentiate the glucose response between normal animals and those with diabetes. We also examined the pattern in glucose fluctuation induced by stress according to type of diabetes.Met
Externí odkaz:
https://doaj.org/article/747bb55e6733418bbf8eca6cda5a84f0
Autor:
Ji-Won Kim, Shin-Young Park, Young-Hye You, Dong-Sik Ham, Seung-Hwan Lee, Hae Kyung Yang, In-Kyung Jeong, Seung-Hyun Ko, Kun-Ho Yoon
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0163187 (2016)
Pancreatic stellate cells (PSCs) play a major role to fibrotic islet destruction observed in diabetic patients and animal model of diabetes. Exendin-4 (Ex-4) is a potent insulinotropic agent and has been approved for the treatment of type 2 diabetes.
Externí odkaz:
https://doaj.org/article/34b42b127c8d43a4afb080cf6a9e8f85
Publikováno v:
Journal of Drug Targeting. 29:88-98
Islet transplantation (ITx) is being developed as a treatment for type 1 diabetes mellitus, but hypoxic damage to transplanted islet grafts is an important factor affecting successful transplantation. To investigate the role of sirtuin-1 (SIRT1) unde
Publikováno v:
Diabetes & Metabolism Journal, Vol 35, Iss 2, Pp 119-129 (2011)
BackgroundA limitation in the number of insulin-producing pancreatic beta-cells is a special feature of diabetes. The identification of alternative sources for the induction of insulin-producing surrogate beta-cells is a matter of profound importance
Externí odkaz:
https://doaj.org/article/0e33e6e34b5f4843ba034d8b1364464f
Autor:
Gyeong-Jin Cheon, Heon-Seok Park, Eun-Young Lee, Min Jung Kim, Young-Hye You, Marie Rhee, Ji-Won Kim, Kun-Ho Yoon
Publikováno v:
Diabetesmetabolism journal. 46(5)
Background: Neonatal porcine pancreatic cell clusters (NPCCs) have been proposed as an alternative source of β cells for islet transplantation because of their low cost and growth potential after transplantation. However, the delayed glucose lowerin