Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Young Ho Byun"'
Autor:
Young-Seok Kim, Ahyun Son, Jihoon Kim, Soon Bin Kwon, Myung Hee Kim, Paul Kim, Jieun Kim, Young Ho Byun, Jemin Sung, Jinhee Lee, Ji Eun Yu, Chan Park, Yeon-Sook Kim, Nam-Hyuk Cho, Jun Chang, Baik L. Seong
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The folding of monomeric antigens and their subsequent assembly into higher ordered structures are crucial for robust and effective production of nanoparticle (NP) vaccines in a timely and reproducible manner. Despite significant advances in in silic
Externí odkaz:
https://doaj.org/article/7d5a9fc141994285863439d81f58903e
Autor:
Yo Han Jang, Joo Young Kim, Young Ho Byun, Ahyun Son, Jeong-Yoon Lee, Yoon Jae Lee, Jun Chang, Baik Lin Seong
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Influenza virus infections continually pose a major public health threat with seasonal epidemics and sporadic pandemics worldwide. While currently licensed influenza vaccines provide only strain-specific protection, antigenic drift and shift occasion
Externí odkaz:
https://doaj.org/article/b262b80950804234b583482b3eb17849
Autor:
Hye Min Lee, Soon Bin Kwon, Ahyun Son, Doo Hyun Kim, Kyun-Hwan Kim, Jonghyo Lim, Young-Guen Kwon, Jin Sun Kang, Byung Kyu Lee, Young Ho Byun, Baik L. Seong
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2847 (2019)
Intrinsic disorders are a common feature of hub proteins in eukaryotic interactomes controlling the signaling pathways. The intrinsically disordered proteins (IDPs) are prone to misfolding, and maintaining their functional stability remains a major c
Externí odkaz:
https://doaj.org/article/ae036d1d0703472ab9581ec1b8868729
Autor:
Yo Han Jang, Young Ho Byun, Kwang-Hee Lee, Eun-Sook Park, Yun Ha Lee, Yoon-Jae Lee, Jinhee Lee, Kyun-Hwan Kim, Baik Lin Seong
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75043 (2013)
Live attenuated vaccine (LAV), mimicking natural infection, provides an excellent protection against microbial infection. The development of LAV, however, still remains highly empirical and the rational design of clinically useful LAV is scarcely ava
Externí odkaz:
https://doaj.org/article/efaa3de3fbb64878b97a2f7c5e4bf9dd
Autor:
Eun-Do Kim, Soo Jung Han, Young-Ho Byun, Sang Chul Yoon, Kyoung Sub Choi, Baik Lin Seong, Kyoung Yul Seo
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137608 (2015)
The eye route has been evaluated as an efficient vaccine delivery routes. However, in order to induce sufficient antibody production with inactivated vaccine, testing of the safety and efficacy of the use of inactivated antigen plus adjuvant is neede
Externí odkaz:
https://doaj.org/article/592f55f506c84ce4838db16255815280
Autor:
Hae-Jung Park, Boris Ferko, Young-Ho Byun, Joo-Hye Song, Gye-Yeong Han, Elisabeth Roethl, Andrej Egorov, Thomas Muster, Baiklin Seong, Mi-Na Kweon, Manki Song, Cecil Czerkinsky, Huan H Nguyen
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39921 (2012)
The nonstructural protein 1 (NS1) of influenza A virus (IAV) enables the virus to disarm the host cell type 1 IFN defense system. Mutation or deletion of the NS1 gene leads to attenuation of the virus and enhances host antiviral response making such
Externí odkaz:
https://doaj.org/article/b0511f0df3d7418ca52e1076f2754670
Autor:
Sang-Uk Seo, Hyung-Joon Kwon, Hyun-Jeong Ko, Young-Ho Byun, Baik Lin Seong, Satoshi Uematsu, Shizuo Akira, Mi-Na Kweon
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001304 (2011)
Type I interferon (IFN-I) plays a critical role in the homeostasis of hematopoietic stem cells and influences neutrophil influx to the site of inflammation. IFN-I receptor knockout (Ifnar1⁻/⁻) mice develop significant defects in the infiltration
Externí odkaz:
https://doaj.org/article/1be4530995784fb6beb466ce71f8c488
Autor:
Byoung-Shik Shim, Young Ki Choi, Cheol-Heui Yun, Eu-Gene Lee, Yoon Seong Jeon, Sung-Moo Park, In Su Cheon, Dong-Hyun Joo, Chung Hwan Cho, Min-Suk Song, Sang-Uk Seo, Young-Ho Byun, Hae-Jung Park, Haryoung Poo, Baik Lin Seong, Jae Ouk Kim, Huan Huu Nguyen, Konrad Stadler, Dong Wook Kim, Kee-Jong Hong, Cecil Czerkinsky, Man Ki Song
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27953 (2011)
BackgroundThe ectodomain of matrix protein 2 (M2e) of influenza A virus is a rationale target antigen candidate for the development of a universal vaccine against influenza as M2e undergoes little sequence variation amongst human influenza A strains.
Externí odkaz:
https://doaj.org/article/672b846a88ac4c83937f716af3e0d5df
Autor:
Young Ho Byun, Jonghyo Lim, Young Guen Kwon, Baik Lin Seong, Kyun-Hwan Kim, Byung Kyu Lee, Ahyun Son, Doo Hyun Kim, Soon Bin Kwon, Hye-Min Lee, Jin Sun Kang
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2847 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 11
International Journal of Molecular Sciences
Volume 20
Issue 11
Intrinsic disorders are a common feature of hub proteins in eukaryotic interactomes controlling the signaling pathways. The intrinsically disordered proteins (IDPs) are prone to misfolding, and maintaining their functional stability remains a major c
Autor:
Yoon Jae Lee, Young Ho Byun, Yo Han Jang, Baik Lin Seong, Kyusik Kim, Kwang Hee Lee, Young Jae Lee, Yun Ha Lee, Paul Kim
Publikováno v:
Virology. 491:1-9
In our previous study, X-31ca-based H5N1 LAIVs, in particular, became more virulent in mice than the X-31ca MDV, possibly by the introduction of the surface antigens of highly pathogenic H5N1 influenza virus, implying that additional attenuation is n