Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Young Hee Choi"'
Autor:
Seung Yon Han, Jeong-Eun Yu, Byoung Hoon You, Seo-Yeon Kim, Mingoo Bae, Hee-Sung Chae, Young-Won Chin, Soo-Hwa Hong, Ju-Hee Lee, Seung Hyun Jung, Young Hee Choi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16677 (2023)
Trastuzumab is used to treat breast cancer patients overexpressing human epidermal growth factor receptor 2, but resistance and toxicity limit its uses, leading to attention to trastuzumab combinations. Recently, the synergistic effect of trastuzumab
Externí odkaz:
https://doaj.org/article/386c84a0f6b24443a3917b4ecd70ef83
Autor:
Choong Whan Lee, Byoung Hoon You, Sreymom Yim, Seung Yon Han, Hee-Sung Chae, Mingoo Bae, Seo-Yeon Kim, Jeong-Eun Yu, Jieun Jung, Piseth Nhoek, Hojun Kim, Han Seok Choi, Young-Won Chin, Hyun Woo Kim, Young Hee Choi
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Metformin as an oral glucose-lowering drug is used to treat type 2 diabetic mellitus. Considering the relatively high incidence of cardiovascular complications and other metabolic diseases in diabetic mellitus patients, a combination of metformin plu
Externí odkaz:
https://doaj.org/article/be0f3aa1c24744ada15f7c1d1b096b69
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2277 (2023)
Mirabegron (MBR) is a β3-adrenoceptor agonist used for treating overactive bladder syndrome. Due to its poor solubility and low bioavailability (F), the development of novel MBR formulations has garnered increasing attention. Recently, co-amorphous
Externí odkaz:
https://doaj.org/article/b2fcb3f8333340c39f0a54390dbeeebd
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2167 (2023)
Febuxostat (FBX), a selective xanthine oxidase inhibitor, belongs to BCS class II, showing low solubility and high permeability with a moderate F value (F) values of FBX were 210% and 159% in FBX-PG-treated rats and mice, respectively. The 2.10-fold
Externí odkaz:
https://doaj.org/article/dc425f5debcc449b8107e262e0c3f9ea
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1392 (2023)
Tenofovir (TEV) is a nucleotide reverse transcriptase inhibitor used against human immunodeficiency virus (HIV) reverse transcriptase. To improve the poor bioavailability of TEV, TEV disoproxil (TD), an ester prodrug of TEV, was developed, and TD fum
Externí odkaz:
https://doaj.org/article/02bd8c0ac9d445618521f861c01f58ac
Publikováno v:
ACS Omega, Vol 5, Iss 48, Pp 31126-31136 (2020)
Externí odkaz:
https://doaj.org/article/cb46e0d2b36742228d7dedc3bede9678
Autor:
Phuong Linh Nguyen, Ahmed Elkamhawy, Young Hee Choi, Chang Hoon Lee, Kyeong Lee, Jungsook Cho
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9903 (2022)
Pharmacological inhibition of the enzyme activity targeting carbonic anhydrases (CAs) demonstrated antiglaucoma and anticancer effects through pH control. Recently, we reported a series of indole-based benzenesulfonamides as potent CA inhibitors. The
Externí odkaz:
https://doaj.org/article/2518a8d8237144059350b31ce59bd65b
Autor:
Hee-Sung Chae, Byoung Hon You, Junjeong Choi, Young-Won Chin, Hojun Kim, Han Seok Choi, Young Hee Choi
Publikováno v:
Journal of Functional Foods, Vol 62, Iss , Pp - (2019)
Ginseng berry extract contains plenty of ginsenosides showing anti-obesity and anti-hyperglycemic activities. Regarding that long-term intakes of herbal products to control metabolic disorders as popular alternatives have become popular, ginseng berr
Externí odkaz:
https://doaj.org/article/de1479415e3448a6930d8cf19c8b0728
Autor:
Hee-Sung Chae, Byoung Hoon You, Dong-Yeop Kim, Hankyu Lee, Hyuk Wan Ko, Hyun-Jeong Ko, Young Hee Choi, Sun Shim Choi, Young-Won Chin
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Whole-transcriptome analysis and western blotting of sauchinone-treated HepG2 cells demonstrated that sauchinone regulated genes relevant to cholesterol metabolism and synthesis. In particular, it was found that the expression of proprotein
Externí odkaz:
https://doaj.org/article/88c1acd2a8594bb8aeaab7ad3b865b1a
Autor:
Mingoo Bae, Seung Yon Han, Eun-Sun Kim, Byung Hoon You, Young-Mi Kim, Jungsook Cho, Young-Won Chin, Young Hee Choi
Publikováno v:
Molecules, Vol 26, Iss 17, p 5246 (2021)
The pharmacokinetic (PK) change in a drug by co-administered herbal products can alter the efficacy and toxicity. In the circumstances that herb–drug combinations have been increasingly attempted to alleviate Alzheimer’s disease (AD), the PK eval
Externí odkaz:
https://doaj.org/article/f639b72d65054165bc0fe40086c21375