Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Young H Sohn"'
Autor:
Jin Yong Hong, Mun Kyung Sunwoo, Jung Han Yoon, Suk Yun Kang, Young H Sohn, Phil Hyu Lee, Seo Hyun Kim
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237472 (2020)
A higher levodopa dose is a strong risk factor for levodopa-induced dyskinesia (LID) in patients with Parkinson's disease (PD). However, levodopa dose can change during long-term medication. We explored the relationship between levodopa dose and time
Externí odkaz:
https://doaj.org/article/a3b81203ed7d4e8a96db59a53ced12d2
Autor:
Yoonju Lee, Jungsu S Oh, Seok Jong Chung, Jae Jung Lee, Su Jin Chung, Hyojeong Moon, Phil Hyu Lee, Jae Seung Kim, Young H Sohn
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203303 (2018)
Depression frequently accompanies Parkinson's disease and often precedes the onset of motor symptoms. This study aimed to evaluate the impact of depression on motor compensation in patients with de novo Parkinson's disease. This retrospective cohort
Externí odkaz:
https://doaj.org/article/1b4c6105bd2149de84a1903f2f43c2e7
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161316 (2016)
The mechanism underlying non-motor symptoms in Parkinson's disease has not yet been elucidated. In this study, we hypothesized that Parkinson patients with more non-motor symptoms have a different pattern of striatal dopamine depletion, particularly
Externí odkaz:
https://doaj.org/article/9c49f8b593cc4a77a04557d17709c55c
Autor:
Jun Kyu Mun, Jinyoung Youn, Jin Whan Cho, Eung-Seok Oh, Ji Sun Kim, Suyeon Park, Wooyoung Jang, Jin Se Park, Seong-Beom Koh, Jae Hyeok Lee, Hee Kyung Park, Han-Joon Kim, Beom S Jeon, Hae-Won Shin, Sun-Ah Choi, Sang Jin Kim, Seong-Min Choi, Ji-Yun Park, Ji Young Kim, Sun Ju Chung, Chong Sik Lee, Tae-Beom Ahn, Won Chan Kim, Hyun Sook Kim, Sang Myung Cheon, Jae Woo Kim, Hee-Tae Kim, Jee-Young Lee, Eun-Joo Kim, Jong-Min Kim, Kwang Soo Lee, Joong-Seok Kim, Min-Jeong Kim, Jong Sam Baik, Ki-Jong Park, Hee Jin Kim, Mee Young Park, Ji Hoon Kang, Sook Kun Song, Yong Duk Kim, Ji Young Yun, Ho-Won Lee, In-Uk Song, Young H Sohn, Phil Hyu Lee, Jeong-Ho Park, Hyung Geun Oh, Kun Woo Park, Do-Young Kwon
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162254 (2016)
Despite the clinical impact of non-motor symptoms (NMS) in Parkinson's disease (PD), the characteristic NMS in relation to the motor subtypes of PD is not well elucidated. In this study, we enrolled drug-naïve PD patients and compared NMS between PD
Externí odkaz:
https://doaj.org/article/22e83ff02f354480b891e9d6fa76c87e
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157410 (2016)
Functional neuroimaging for the dopamine transporter (DAT) is used to distinguish drug-induced parkinsonism (DIP) from subclinical Parkinson's disease (PD). Although DIP patients who show a normal DAT image are expected to recover completely, some do
Externí odkaz:
https://doaj.org/article/96a14a827d5a452fa2299e8e79a06c14
Autor:
Seong Ho Jeong, Jungho Cha, Han Soo Yoo, Seok Jong Chung, Jin Ho Jung, Young H. Sohn, Phil Hyu Lee
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Patients with dementia with Lewy bodies (DLB) show widespread brain metabolic changes. This study investigated whether brain hypo- and hypermetabolism in DLB have differential effects on cognition. We enrolled 55 patients with DLB (15 prodro
Externí odkaz:
https://doaj.org/article/c1b933d6ec264451be7f0680c4f1237d
Autor:
Seong Ho Jeong, Seok Jong Chung, Han Soo Yoo, Jin Ho Jung, Jong Sam Baik, Young H. Sohn, Phil Hyu Lee
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Cholesterol is an essential component of the neuronal cell membrane and is crucial for neuronal function; however, the role of cholesterol levels in Parkinson’s disease (PD) is debatable. This study investigated the complex rela
Externí odkaz:
https://doaj.org/article/a05ef9c5f2ff4e69a9cf5a33b0e73778
Autor:
Seok Jong Chung, Hunki Kwon, Dong-Kyun Lee, Jin Yong Hong, Mun-Kyung Sunwoo, Young H Sohn, Jong-Min Lee, Phil Hyu Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84054 (2013)
BACKGROUND: Recent studies have suggested that essential tremor (ET) is a more complex and heterogeneous clinical entity than initially thought. In the present study, we assessed the pattern of cortical thickness and diffusion tensor white matter (WM
Externí odkaz:
https://doaj.org/article/671d014452874b32bc2337db4fa3ce26
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50496 (2012)
BACKGROUND: Modulation of neurogenesis that acts as an endogenous repair mechanism would have a significant impact on future therapeutic strategies for Parkinson's disease (PD). Several studies demonstrated dopaminergic modulation of neurogenesis in
Externí odkaz:
https://doaj.org/article/2f03761d0a754674a2b534308bdf073d
Autor:
Phil Hyu Lee, Han-Soo Kim, Ji E Lee, Youjeong Choi, Jin Yong Hong, Hyo Suk Nam, Young H Sohn, Hyun Ok Kim
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21536 (2011)
BACKGROUND: Levodopa treatment in Parkinson's disease (PD) increases in serum homocysteine levels due to its metabolism via catechol O-methyltransferase. Endothelial progenitor cells (EPCs) have the capacity to differentiate into mature endothelial c
Externí odkaz:
https://doaj.org/article/e5229af5980a4121a34f18fb9bead7b6