Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Young Ger Suh"'
Autor:
Eun Ji Lee, Su-Jung Kim, Young-Il Hahn, Hyo-Jin Yoon, Bitnara Han, Kyeojin Kim, Seungbeom Lee, Kwang Pyo Kim, Young Ger Suh, Hye-Kyung Na, Young-Joon Surh
Publikováno v:
Redox Biology, Vol 23, Iss , Pp - (2019)
Overproduction of prostaglandin E2 (PGE2) has been linked to enhanced tumor cell proliferation, invasiveness and metastasis as well as resistance to apoptosis. 15-Keto prostaglandin E2 (15-keto PGE2), a product formed from 15-hydroxyprostaglandin deh
Externí odkaz:
https://doaj.org/article/1ad8036ce9ce4c94926980e813acbf27
Autor:
Hyun Su Kim, Hyejin Kong, Taewoo Kim, Changjin Lim, Seungbeom Lee, Seok-Ho Kim, Young-Ger Suh
Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 281 (2023)
This study aimed to elucidate the structural congeners of natural izenamides A, B, and C (1–3) responsible for cathepsin D (CTSD) inhibition. Structurally modified izenamides were synthesized and biologically evaluated, and their biologically impor
Externí odkaz:
https://doaj.org/article/3d0321274dbe4b529d34a2e1c2d6eb62
Autor:
Kyoung Song, Nirmal Rajasekaran, Chaithanya Chelakkot, Hun Seok Lee, Seung-Mann Paek, Hobin Yang, Lina Jia, Hee Geon Park, Woo Sung Son, Yu-Jin Kim, Joon-Seok Choi, Hae Min Jeong, Young-Ger Suh, Hwayoung Yun, Young Kee Shin
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1060 (2021)
Aerobic glycolysis in cancer cells, also known as the Warburg effect, is an indispensable hallmark of cancer. This metabolic adaptation of cancer cells makes them remarkably different from normal cells; thus, inhibiting aerobic glycolysis is an attra
Externí odkaz:
https://doaj.org/article/a3cd02d1a0b14c19bfd1763848ecc314
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8813 (2021)
The activation of signal transducer and activator of transcription 3 (STAT3), as well as up-regulation of cytokines and growth factors to promote STAT3 activation, have been found in the epidermis of psoriatic lesions. Recently, a series of synthetic
Externí odkaz:
https://doaj.org/article/85dfbdcbfae74f5daacf52b3b941802f
Autor:
Seong Hoon Kim, Hye-Won Yum, Seung Hyeon Kim, Su-Jung Kim, Kyeojin Kim, Chaekyun Kim, Young-Ger Suh, Young-Joon Surh
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 867 (2021)
Excessive exposure to solar light, especially its UV component, is a principal cause of photoaging, dermatitis, and photocarcinogenesis. In searching for candidate substances that can effectively protect the skin from photodamage, the present study w
Externí odkaz:
https://doaj.org/article/2d49911c737942f888cc9096e6321e3d
Autor:
Bum-Joon Park, Hwayoung Yun, Yonghoon Kwon, Bae-Hoon Kim, Young-Ger Suh, Young Taek Han, Heegyu Kim, Yeong Hye Park, Myeonggyo Jeong, Hyunkee Lee, Min-Ho Yoon, Tae-Gyun Woo, So-Mi Kang, Soyeong Kim, Soyoung Park, Jung-Hyun Cho
Supplementary Data from RKIP Induction Promotes Tumor Differentiation via SOX2 Degradation in NF2-Deficient Conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c45c26fccae5cd25e9c67cbea789d8
https://doi.org/10.1158/1541-7786.22528047
https://doi.org/10.1158/1541-7786.22528047
Autor:
Ho-Young Lee, Young-Ger Suh, Waun Ki Hong, Kyu-Won Kim, Gordon Mills, Seung-Yong Geo, Hyun-Ju Park, Yoo-Shin Kim, Seung-Ho Han, Jakyung Yoo, Hae Jin Kang, Bryan Hennessy, Dong Jo Chang, Woo-Young Kim
Supplementary Table 1 from A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ef6c9aaafc1a0de0b3c5ad317fa8f7
https://doi.org/10.1158/1940-6207.22523046.v1
https://doi.org/10.1158/1940-6207.22523046.v1
Autor:
Ho-Young Lee, Young-Ger Suh, Waun Ki Hong, Kyu-Won Kim, Gordon Mills, Seung-Yong Geo, Hyun-Ju Park, Yoo-Shin Kim, Seung-Ho Han, Jakyung Yoo, Hae Jin Kang, Bryan Hennessy, Dong Jo Chang, Woo-Young Kim
The natural compound deguelin has promising preventive and therapeutic activity against diverse cancers by directly binding to heat shock protein-90 and thus suppressing its function. Potential side effects of deguelin over a certain dose, however, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4469084713fe39a32d17ed9555387b
https://doi.org/10.1158/1940-6207.c.6543570.v1
https://doi.org/10.1158/1940-6207.c.6543570.v1
Autor:
Ho-Young Lee, Young-Ger Suh, Kyu-Won Kim, Jeeyeon Lee, Jeewoo Lee, Sang Kook Lee, Hyun-Ju Park, Young-Myeong Kim, Seungbeom Lee, Ji Hae Seo, So-Jung Park, Hongchan An, Jun Yong Kim, Shin-Hyung Park, Jayoung Moon, Ho Jin Lee, Seung Yeob Hyun, Kwan Hee Park, Song Yi Bae, Hoon Choi, Hye-Young Min, Su-Chan Lee
The Hsp90 facilitates proper folding of signaling proteins associated with cancer progression, gaining attention as a target for therapeutic intervention. The natural rotenoid deguelin was identified as an Hsp90 inhibitor, but concerns about neurotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114cf21b9cbbd20ce0df81b4685ebc1e
https://doi.org/10.1158/0008-5472.c.6507899.v1
https://doi.org/10.1158/0008-5472.c.6507899.v1
Autor:
Ho-Young Lee, Young-Ger Suh, Kyu-Won Kim, Jeeyeon Lee, Jeewoo Lee, Sang Kook Lee, Hyun-Ju Park, Young-Myeong Kim, Seungbeom Lee, Ji Hae Seo, So-Jung Park, Hongchan An, Jun Yong Kim, Shin-Hyung Park, Jayoung Moon, Ho Jin Lee, Seung Yeob Hyun, Kwan Hee Park, Song Yi Bae, Hoon Choi, Hye-Young Min, Su-Chan Lee
Supplementary Materials and Methods. Supplementary Table 1. The acquisition of drug resistance in several drug resistant cells (designated '/R') upon corresponding anticancer drug treatment. Supplementary Table 2. Docking and scoring known Hsp90 inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcadca4faf4c3e3dc953862a8eaa1a2
https://doi.org/10.1158/0008-5472.22410032
https://doi.org/10.1158/0008-5472.22410032