Výsledky vyhledávání - "Young D, Jung"

Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors

Autor: Christian, Moser, Sven A, Lang, Christina, Hackl, Hong, Zhang, Karen, Lundgren, Victor, Hong, Andres, McKenzie, Bernhard, Weber, Jung S, Park, Hans J, Schlitt, Edward K, Geissler, Young D, Jung, Oliver, Stoeltzing

Publikováno v: Anticancer research. 32(2)

To evaluate the effects of HSP90 blockade by EC154 on the oncogenic receptor tyrosine kinase macrophage-stimulating 1 receptor (MST1R) in gastric and pancreatic cancer.Impact of EC154 on signaling pathways was investigated by western blotting. Cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a14a233e8595cd91dc5477c34814bd78
https://pubmed.ncbi.nlm.nih.gov/22287729

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EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-kappaB signaling in human gastric carcinoma cells

Autor: Min K, Baek, Mi H, Kim, Hee J, Jang, Jung S, Park, Ik J, Chung, Boo A, Shin, Bong W, Ahn, Young D, Jung

Publikováno v: Oncology reports. 20(6)

Overexpression of epidermal growth factor (EGF) and urokinase plasminogen activator receptor (uPAR) have been observed in human gastric cancers. However, the interaction between EGF and uPAR in gastric cancer has not been well elucidated. In this stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4aff88160702895afaed4a4a37bf73cf
https://pubmed.ncbi.nlm.nih.gov/19020743

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Triptolide inhibits tumor promoter-induced uPAR expression via blocking NF-kappaB signaling in human gastric AGS cells

Autor: Hee J, Chang, Mi H, Kim, Min K, Baek, Jung S, Park, Ik J, Chung, Boo A, Shin, Bong W, Ahn, Young D, Jung

Publikováno v: Anticancer research. 27(5A)

The overexpression of urokinase-type plasminogen activator receptor (uPAR) is closely related to tumor cell invasion. Therefore, strategies for down-regulating uPAR expression may be of clinical utility. This study examined the effects of triptolide,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26c33bd2a8339135c797b1c32eb4d9eb
https://pubmed.ncbi.nlm.nih.gov/17970088

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Helicobacter pylori stimulates urokinase plasminogen activator receptor expression and cell invasiveness through reactive oxygen species and NF-kappaB signaling in human gastric carcinoma cells

Autor: Mi H, Kim, Hyung S, Yoo, Mi Y, Kim, Hee J, Jang, Min K, Baek, Hyeong R, Kim, Kyung K, Kim, Boo A, Shin, Bong W, Ahn, Young D, Jung

Publikováno v: International journal of molecular medicine. 19(4)

The gastric pathogen, helicobacter pylori (H. pylori), has been associated with the progression of gastric cancer. It was previously reported that H. pylori induced urokinase plasminogen activator receptor (uPAR) expression and stimulated cell invasi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7cdb84d0a3261b25046a141160d1bd6
https://pubmed.ncbi.nlm.nih.gov/17334646

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Epigallocatechin-3-gallate inhibits the PDGF-induced VEGF expression in human vascular smooth muscle cells via blocking PDGF receptor and Erk-1/2

Autor: Jung S, Park, Mi H, Kim, Hee J, Chang, Ki M, Kim, Seok M, Kim, Boo A, Shin, Bong W, Ahn, Young D, Jung

Publikováno v: International journal of oncology. 29(5)

Platelet-derived growth factor (PDGF) has been known to induce vascular endothelial growth factor (VEGF) expression in human vascular smooth muscle cells (hVSMCs). We previously reported that Erk-1/2 and AP-1 pathways are crucial in the PDGF-induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::249251b4cad8b36dfe7313f1e9674810
https://pubmed.ncbi.nlm.nih.gov/17016658

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Extracellular signal-regulated kinases and AP-1 mediate the up-regulation of vascular endothelial growth factor by PDGF in human vascular smooth muscle cells

Autor: Hee J, Chang, Jung S, Park, Mi H, Kim, Min H, Hong, Ki M, Kim, Seok M, Kim, Boo A, Shin, Bong W, Ahn, Young D, Jung

Publikováno v: International journal of oncology. 28(1)

Endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) have been shown to communicate with each other via cytokine signaling during neovascularization. In this study, we investigated the effect of platelet-derived growth factor (PDGF), a cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0021696acb5eed827a5cb9c78fb4f2a9
https://pubmed.ncbi.nlm.nih.gov/16327989

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Extracellular signal-regulated kinase and AP-1 pathways are involved in reactive oxygen species-induced urokinase plasminogen activator receptor expression in human gastric cancer cells

Autor: Mi H, Kim, Hyung S, Cho, Min, Jung, Min H, Hong, Sam K, Lee, Boo A, Shin, Bong W, Ahn, Young D, Jung

Publikováno v: International journal of oncology. 26(6)

Overexpression of urokinase plasminogen activator receptor (uPAR) is known to correlate closely with tumor cell invasion and metastasis. In gastric cancer, however, the mechanism for induction of uPAR remains to be elucidated. In this study, to inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2cd607ebbb453056890171412b95cd48
https://pubmed.ncbi.nlm.nih.gov/15870884

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EGCG blocks tumor promoter-induced MMP-9 expression via suppression of MAPK and AP-1 activation in human gastric AGS cells

Autor: Hong S, Kim, Mi H, Kim, Min, Jeong, Young S, Hwang, Sun H, Lim, Boo A, Shin, Bong W, Ahn, Young D, Jung

Publikováno v: Anticancer research. 24(2B)

Overexpression of matrix metalloproteinases (MMPs) has been known to correlate closely with tumor cell invasion and strategies to down-regulate their expression may ultimately be of clinical utility. In this study, we investigated the effects of (-)-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd8bd924834a9e9c3bdbc5c23f93c717
https://pubmed.ncbi.nlm.nih.gov/15161022

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Involvement of NF-kappaB and caspases in silibinin-induced apoptosis of endothelial cells

Autor: Hyeon G, Yoo, Sung N, Jung, Young S, Hwang, Jung S, Park, Mi H, Kim, Min, Jeong, Sung J, Ahn, Bong W, Ahn, Boo A, Shin, Rae K, Park, Young D, Jung

Publikováno v: International journal of molecular medicine. 13(1)

Silibinin, the flavonoid found in the milk thistle, has been shown to suppress cell growth and exhibit anti-cancer effects. Some flavonoids were reported to inhibit angiogenesis which is essential for tumor growth and metastasis. In this study, to cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07710efe43147e47d3fa9bafbd5a08dc
https://pubmed.ncbi.nlm.nih.gov/14654975

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Angiogenesis and antiangiogenic therapy of colon cancer liver metastasis

Autor: Oliver, Stoeltzing, Wenbiao, Liu, Niels, Reinmuth, Alexander, Parikh, Syed A, Ahmad, Young D, Jung, Fan, Fan, Lee M, Ellis

Publikováno v: Annals of surgical oncology. 10(7)

The fact that tumor growth and metastatic spread relies on angiogenesis has been widely proven and accepted. The understanding of cancer biology and metastasis formation has led to the development of new therapeutic approaches that target tumor biolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9e17c88350281200de78f0cb80f40a85
https://pubmed.ncbi.nlm.nih.gov/12900362

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