Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Young Chan Chae"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 4, Pp 877-889 (2024)
Abstract Extracellular vesicles (EVs), including exosomes, are increasingly recognized as potent mediators of intercellular communication due to their capacity to transport a diverse array of bioactive molecules. They assume vital roles in a wide ran
Externí odkaz:
https://doaj.org/article/d4cc615c319e4c5098d6cb3303ffe4b8
Autor:
Hye Yun Kim, Jieun Lee, Hyun-Jin Kim, Byeong Eun Lee, Jaewook Jeong, Eun Jeong Cho, Hyun-Jun Jang, Kyeong Jin Shin, Min Ji Kim, Young Chan Chae, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Pann-Ghill Suh, Jae-Ick Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 11, Pp 2357-2375 (2023)
Abstract Dopamine neurons are essential for voluntary movement, reward learning, and motivation, and their dysfunction is closely linked to various psychological and neurodegenerative diseases. Hence, understanding the detailed signaling mechanisms t
Externí odkaz:
https://doaj.org/article/9bf57bd326b342e499039a5360ea2560
Autor:
Hyun-Jun Jang, Yo Han Lee, Tam Dao, Yunju Jo, Keon Woo Khim, Hye-jin Eom, Ju Eun Lee, Yi Jin Song, Sun Sil Choi, Kieun Park, Haneul Ji, Young Chan Chae, Kyungjae Myung, Hongtae Kim, Dongryeol Ryu, Neung Hwa Park, Sung Ho Park, Jang Hyun Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 8, Pp 1720-1733 (2023)
Abstract Autophagy functions in cellular quality control and metabolic regulation. Dysregulation of autophagy is one of the major pathogenic factors contributing to the progression of nonalcoholic fatty liver disease (NAFLD). Autophagy is involved in
Externí odkaz:
https://doaj.org/article/d56a7edfec494605a5705df2ce84a1d6
Autor:
Wonyoung Park, Shibo Wei, Bo-Sung Kim, Bosung Kim, Sung-Jin Bae, Young Chan Chae, Dongryeol Ryu, Ki-Tae Ha
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 8, Pp 1573-1594 (2023)
Abstract Death is the inevitable fate of all living organisms, whether at the individual or cellular level. For a long time, cell death was believed to be an undesirable but unavoidable final outcome of nonfunctioning cells, as inflammation was inevi
Externí odkaz:
https://doaj.org/article/34c7dc290c214b6aaf8bab2b85dd3bfa
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102444- (2023)
Summary: Exosomes mediate intracellular communication between cancer cells and the local/distant microenvironment, which promotes systemic dissemination of cancer. Here, we present a protocol for tumor-derived exosome isolation and in vivo metastasis
Externí odkaz:
https://doaj.org/article/95f05d24e1a1473ea066d706f143ea3c
Autor:
Wonyoung Park, Shibo Wei, Bo-Sung Kim, Bosung Kim, Sung-Jin Bae, Young Chan Chae, Dongryeol Ryu, Ki-Tae Ha
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 9, Pp 2083-2083 (2023)
Externí odkaz:
https://doaj.org/article/8726a596639e4c10a49c8a9a455a6975
Autor:
Seongchun Min, Ji Yeon Kim, Hyo Min Cho, Sujin Park, Ji Min Hwang, Hyejin You, Young Chan Chae, Won-Jae Lee, Woong Sun, Dongmin Kang, Sanghyuk Lee, Sang Won Kang
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102293- (2022)
Mitochondria communicate with other cellular compartments via the secretion of protein factors. Here, we report an unexpected messenger role for heat shock protein 60 (HSP60) as a mitochondrial-releasing protein factor that couples stress-sensing sig
Externí odkaz:
https://doaj.org/article/43ec98d44e8e48cea147fe1ac79e4aca
Autor:
Yu Geon Lee, Hui Won Kim, Yeji Nam, Kyeong Jin Shin, Yu Jin Lee, Do Hong Park, Hyun-Woo Rhee, Jeong Kon Seo, Young Chan Chae
Publikováno v:
Oncogenesis, Vol 10, Iss 2, Pp 1-14 (2021)
Abstract Mitochondrial proteases are key components in mitochondrial stress responses that maintain proteostasis and mitochondrial integrity in harsh environmental conditions, which leads to the acquisition of aggressive phenotypes, including chemore
Externí odkaz:
https://doaj.org/article/5c7fcc2ca8cf4c05babd39badab60e0e
Autor:
Sun Sil Choi, Sang Kwon Lee, Joong Kwan Kim, Hye-Kyung Park, Eujin Lee, Jinho Jang, Yo Han Lee, Keon Woo Khim, Ji-Min Hyun, Hye-jin Eom, Semin Lee, Byuong Heon Kang, Young Chan Chae, Kyungjae Myung, Seung-Jae Myung, Chan Young Park, Jang Hyun Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 6, Pp 940-950 (2020)
Cancer: Protein enhances survival of tumor cells under stress A cytoskeletal protein that helps tumors avoid cell death offers a promising new drug target for fighting cancer. A team led by Jang Hyun Choi and Sun Sil Choi of the Ulsan National Instit
Externí odkaz:
https://doaj.org/article/c7f168302e994500b72ed662e3ac19d8
Autor:
Hye-Kyung Park, Nam Gu Yoon, Ji-Eun Lee, Sung Hu, Sora Yoon, So Yeon Kim, Jun-Hee Hong, Dougu Nam, Young Chan Chae, Jong Bae Park, Byoung Heon Kang
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 1, Pp 79-91 (2020)
Cancer therapeutics: Extending a drug’s reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment. Several drugs have targeted HSPs, since
Externí odkaz:
https://doaj.org/article/35a514c7ab004b988412156186b7dc41