Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Young Bok (Abraham) Kang"'
Publikováno v:
Micromachines, Vol 8, Iss 1, p 27 (2017)
We have developed a miniature human liver (liver-sinusoid-on-a-chip) model using a dual microchannel separated by a porous membrane. Primary human hepatocytes and immortalized bovine aortic endothelial cells were co-cultured on opposite sides of a mi
Externí odkaz:
https://doaj.org/article/a2be50c429064bac888cccc44dcf36ca
Publikováno v:
Biotechnol Bioeng
Oxygen is vital to the function of all tissues including the liver and lack of oxygen, i.e. hypoxia, can result in both acute and chronic injuries to the liver in vivo and ex vivo. Furthermore, a permanent oxygen gradient is naturally present along t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496cda10ad1dbb5fd8489a420b5ff5d1
https://doi.org/10.1002/bit.27225
https://doi.org/10.1002/bit.27225
Autor:
Beyza Bulutoglu, Martin L. Yarmush, O. Berk Usta, Camilo Rey-Bedón, Safak Mert, Young Bok Abraham Kang
Publikováno v:
Lab Chip
Non-alcoholic fatty liver disease (NAFLD) and its progressive form non-alcoholic steatohepatitis (NASH) affect 25% of the world population. NAFLD is predicted to soon become the main cause of liver morbidity and transplantation. The disease is charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7d6290b6a78dea751d156f7255f931
https://doi.org/10.1039/c9lc00354a
https://doi.org/10.1039/c9lc00354a
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Poly(dimethylsiloxane) (PDMS) is likely the most popular material for microfluidic devices in lab-on-a-chip and other biomedical applications. However, the hydrophobicity of PDMS leads to non-specific adsorption of proteins and other molecules such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aab9e03eb7a81cc2ed97927408d6644
http://hdl.handle.net/11655/24648
http://hdl.handle.net/11655/24648
Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
An important number of healthy and diseased tissues shows spatial variations in their metabolic capacities across the tissue. The liver is a prime example of such heterogeneity where the gradual changes in various metabolic activities across the live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3c194a63f308cc4fbd198e029ce3b6
https://doi.org/10.1038/s41598-018-27179-6
https://doi.org/10.1038/s41598-018-27179-6
Publikováno v:
Micromachines, Vol 8, Iss 1, p 27 (2017)
Micromachines
Micromachines; Volume 8; Issue 1; Pages: 27
Micromachines
Micromachines; Volume 8; Issue 1; Pages: 27
We have developed a miniature human liver (liver-sinusoid-on-a-chip) model using a dual microchannel separated by a porous membrane. Primary human hepatocytes and immortalized bovine aortic endothelial cells were co-cultured on opposite sides of a mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c475189e44c51e00f329c78997bd4527
http://www.mdpi.com/2072-666X/8/1/27
http://www.mdpi.com/2072-666X/8/1/27
Autor:
Yung-Hum Yang, Kwangkyung Liou, Jae Kyung Sohng, Tek-Hyung Lee, Kwangwon Lee, Hee-Chan Lee, Byung-Gee Kim, Young Bok Abraham Kang, Dongwon Yoo, Sung-Hee Park, Dae-Hee Kim
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 62:282-287
Production of deoxy-thymidine-diphosphate (TDP)-sugars as substrates of glycosyltransferases, has been one of main hurdles for combinatorial antibiotic biosynthesis, which combines sugar moiety with aglycon of various antibiotics. Here, we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8219831ddc07e67d55cae0722b27574c
https://doi.org/10.1016/j.molcatb.2009.11.008
https://doi.org/10.1016/j.molcatb.2009.11.008
Autor:
Caroline Rajiv, Jason Lamontagne, Michael J. Bouchard, Temitope R Sodunke, Joseph Cirillo, Moses Noh, Young Bok Abraham Kang
Publikováno v:
Biotechnology and bioengineering. 112(12)
We describe the generation of microfluidic platforms for the co-culture of primary hepatocytes and endothelial cells; these platforms mimic the architecture of a liver sinusoid. This paper describes a progressional study of creating such a liver sinu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02b3bb18f06a602d6e817adb37b8f49
https://pubmed.ncbi.nlm.nih.gov/25994312
https://pubmed.ncbi.nlm.nih.gov/25994312
Autor:
Kwangwon Lee, Jae Kyung Sohng, Yung-Hun Yang, Kwangkyoung Liou, Young Bok Abraham Kang, Sun-Gu Lee, Byung-Gee Kim, Hei Chan Lee
Publikováno v:
Biotechnology and Bioengineering. 93:21-27
dTDP-L-rhamnose, an important precursor of O-antigen, was prepared on a large scale from dTMP by executing an one-pot reaction in which six enzymes are involved. Two enzymes, dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase and dTDP-4-keto-rhamnose reduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65e16dbdeddb5c3c932f23858108550
https://doi.org/10.1002/bit.20648
https://doi.org/10.1002/bit.20648
Autor:
Yousung Jung, Wonsuk Jung, Soohyun Kim, Hongseok (Moses) Noh, Seung Ho Lee, Young Bok Abraham Kang
Publikováno v:
Nanoscale Research Letters
While flow-induced voltage over a graphene layer has been reported, its origin remains unclear. In our previous study, we suggested different mechanisms for different experimental configurations: phonon dragging effect for the parallel alignment and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2335db9c13e81a7e5438ff4ce86b48c8
https://doi.org/10.1186/1556-276x-8-487
https://doi.org/10.1186/1556-276x-8-487