Zobrazeno 1 - 10
of 694
pro vyhledávání: '"Young‐Tae Chang"'
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103279- (2024)
Cellular senescence, which is triggered by various stressors, manifests as irreversible cell cycle arrest, resulting in the disruption of multiple nuclear condensates. One of the affected structures is the nucleolus, whose tripartite layout, separate
Externí odkaz:
https://doaj.org/article/8b7b2ef5a5a241948356699a73973acc
Autor:
Heewon Cho, Haw-Young Kwon, Youngsook Kim, Kyungwon Kim, Eun Jig Lee, Nam-Young Kang, Young-Tae Chang
Publikováno v:
JACS Au, Vol 4, Iss 4, Pp 1450-1457 (2024)
Externí odkaz:
https://doaj.org/article/8601a5501ebf45df9c7565793c04b547
Autor:
Sangbae Park, Juo Lee, Jong-Jin Kim, Moongi Ji, Eunbee Cho, Hyun Bo Sim, Young-Tae Chang, Jong Hoon Chung, Man-Jeong Paik, Jungsil Kim, Hoon Seonwoo
Publikováno v:
Materials & Design, Vol 240, Iss , Pp 112822- (2024)
Although titanium-based metal implants have become a game changer in dental and orthopedic therapies, they still have several problems such as late osseointegration and immune response. In this study, we present a novel strategy to develop Ti6Al4V-ba
Externí odkaz:
https://doaj.org/article/69d5b802cd934631aba0ad80105fbd43
Autor:
Sonia Golombek, Thomas Hoffmann, Ludmilla Hann, Markus Mandler, Sabine Schmidhuber, Josefin Weber, Young-Tae Chang, Roman Mehling, Andrea Ladinig, Christian Knecht, Johanna Leyens, Christian Schlensak, Hans Peter Wendel, Achim Schneeberger, Meltem Avci-Adali
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 642-654 (2023)
Loss of elastin due to aging, disease, or injury can lead to impaired tissue function. In this study, de novo tropoelastin (TE) synthesis is investigated in vitro and in vivo using different TE-encoding synthetic mRNA variants after codon optimizatio
Externí odkaz:
https://doaj.org/article/fb35e12ee64a40e1bef0ae30f9a604f7
Autor:
Seul-Ki Mun, Hyun Bo Sim, Ji Yeon Han, Hyeongyeong Kim, Dae-Han Park, Dong-Jo Chang, Sung-Tae Yee, Young-Tae Chang, Jong-Jin Kim
Publikováno v:
Tomography, Vol 9, Iss 4, Pp 1187-1195 (2023)
The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR
Externí odkaz:
https://doaj.org/article/4ab1bb8c93eb445b9a85c7d4f6b4b7a8
Autor:
Mügen Terzioglu, Kristo Veeroja, Toni Montonen, Teemu O Ihalainen, Tiina S Salminen, Paule Bénit, Pierre Rustin, Young-Tae Chang, Takeharu Nagai, Howard T Jacobs
Publikováno v:
eLife, Vol 12 (2023)
Based on studies with a fluorescent reporter dye, Mito Thermo Yellow (MTY), and the genetically encoded gTEMP ratiometric fluorescent temperature indicator targeted to mitochondria, the temperature of active mitochondria in four mammalian and one ins
Externí odkaz:
https://doaj.org/article/582ec16ea6924628942e3d6071e8abc5
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 424 (2024)
Fluorescent bioprobes are invaluable tools for visualizing live cells and deciphering complex biological processes by targeting intracellular biomarkers without disrupting cellular functions. In addition to protein-binding concepts, fluorescent probe
Externí odkaz:
https://doaj.org/article/eb7bfc7015a04c2187a1aaa0ca7853f9
Autor:
Heewon Cho, Haw-Young Kwon, Amit Sharma, Sun Hyeok Lee, Xiao Liu, Naoki Miyamoto, Jong-Jin Kim, Sin-Hyeog Im, Nam-Young Kang, Young-Tae Chang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Studying the specific roles of macrophage subsets has been hampered by a lack of subset-specific probes. Here the authors report an M1 selective fluorescent probe named CDr17, and demonstrate the suitability of this probe for tracking M1 macrophages
Externí odkaz:
https://doaj.org/article/9d22797d096d44b6b006ce06f63551e8
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Trimethyltin (TMT) is a potent neurotoxicant that leads to hippocampal neurodegeneration. Regulatory T cells (Tregs) play an important role in maintaining the immune balance in the central nervous system (CNS), but their activitie
Externí odkaz:
https://doaj.org/article/fbcab1b541434e66800411472b89288f
Publikováno v:
Chemosensors, Vol 11, Iss 7, p 375 (2023)
Fluorescence thermometry is a microscopy technique in which a fluorescent temperature sensor records temperature changes as alterations of fluorescence signals. Fluorescence lifetime imaging (FLIM) is a promising method for quantitative analysis of i
Externí odkaz:
https://doaj.org/article/86397c1ad8bc4d24b12c4f12a92a0357