Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Younes SM"'
Publikováno v:
Applied Microbiology, Vol 4, Iss 3, Pp 1362-1383 (2024)
The terrestrial biota is a rich source of biologically active substances whose anti-biofilm potential is not studied enough. The aim of this review is to outline a variety of terrestrial sources of antimicrobial agents with the ability to inhibit dif
Externí odkaz:
https://doaj.org/article/d738710336c64eabacf09c21082ccd78
Autor:
Irene Molina-Panadero, Marcos Morales-Tenorio, Alfonso García-Rubia, Tiziana Ginex, Khalil Eskandari, Ana Martinez, Carmen Gil, Younes Smani
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Our aim is to identify new small molecules with antimicrobial potential, especially against colistin-resistant (Col-R) Acinetobacter baumannii and Escherichia coli. After initial hits identification by fingerprint similarity, MIC of 24 heterocyclic d
Externí odkaz:
https://doaj.org/article/c5d65201a6bb4f93b0e75e543b8a7281
Publikováno v:
Molecules, Vol 29, Iss 20, p 4889 (2024)
Conventional antibiotic and multidrug treatments are becoming less and less effective and the discovery of new effective and safe antibacterial agents is becoming a global priority. Returning to a natural antibacterial product is a relatively new cur
Externí odkaz:
https://doaj.org/article/7f6d67625784495291b5c3edc1c372bd
Autor:
Yassir Boulaamane, Irene Molina Panadero, Abdelkrim Hmadcha, Celia Atalaya Rey, Soukayna Baammi, Achraf El Allali, Amal Maurady, Younes Smani
Publikováno v:
mSystems, Vol 9, Iss 6 (2024)
ABSTRACT Global challenges presented by multidrug-resistant Acinetobacter baumannii infections have stimulated the development of new treatment strategies. We reported that outer membrane protein W (OmpW) is a potential therapeutic target in A. bauma
Externí odkaz:
https://doaj.org/article/efb09053dc2f4762a556a4e4e44d2d13
Autor:
Soraya Herrera-Espejo, Andrea Vila-Domínguez, Tania Cebrero-Cangueiro, Younes Smani, Jerónimo Pachón, Manuel E. Jiménez-Mejías, María E. Pachón-Ibáñez
Publikováno v:
Antibiotics, Vol 13, Iss 5, p 386 (2024)
This study aimed to evaluate the potential of tamoxifen and N-desmethyltamoxifen metabolites as therapeutic agents against multidrug-resistant Escherichia coli and Acinetobacter baumannii, using a repurposing approach to shorten the time required to
Externí odkaz:
https://doaj.org/article/ea68df2b9859410d9975e2537749a300
Autor:
Angel Rodríguez Villodres, Lydia Gálvez Benítez, Manuel J. Arroyo, Gema Méndez, Luis Mancera, Andrea Vila Domínguez, José Antonio Lepe Jímenez, Younes Smani
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2034-2044 (2022)
Background The excessive use of piperacillin/tazobactam (P/T) has promoted the emergence of P/T-resistant Enterobacterales. We reported that in Escherichia coli, P/T contributes to the development of extended-spectrum resistance to β-lactam/β-lacta
Externí odkaz:
https://doaj.org/article/5f66a0c7be00466c856ca82d704cf51c
Autor:
María Tomás, Younes Smani
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/026341dcd76f4b448ee924f2194682bf
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Acinetobacter baumannii needs to adapt to hypoxia during infection. Understanding its proteome regulation during infection would allow us to determine new targets to develop novel treatments. iTRAQ proteomic analysis of A549 cell infection b
Externí odkaz:
https://doaj.org/article/1a3a0fac10ec43479688a037d1b45bf7
Autor:
Isabel Mayoral, Elisa Bevilacqua, Gorka Gómez, Abdelkrim Hmadcha, Ignacio González-Loscertales, Esther Reina, Julio Sotelo, Antonia Domínguez, Pedro Pérez-Alcántara, Younes Smani, Patricia González-Puertas, Ana Mendez, Sergio Uribe, Tarik Smani, Antonio Ordoñez, Israel Valverde
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100252- (2022)
Three-dimensional (3D) engineered cardiovascular tissues have shown great promise to replace damaged structures. Specifically, tissue engineering vascular grafts (TEVG) have the potential to replace biological and synthetic grafts. We aimed to design
Externí odkaz:
https://doaj.org/article/442e641e63dc4304a42882b0e2fda4e1
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/22769ec077334a51baecfaf178d854b0