Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Younes, Larsen"'
Autor:
Christian B. M. Poulie, Younes Larsen, Cindie Leteneur, Gaël Barthet, Walden E. Bjørn-Yoshimoto, Fanny Malhaire, Birgitte Nielsen, Jean-Phillippe Pin, Christophe Mulle, Darryl S. Pickering, Lennart Bunch
Publikováno v:
ACS Chemical Neuroscience. 13:1580-1587
Autor:
Jacob C. Hansen, Silke Kayser, Kasper B. Hansen, Stylianos Iliadis, Niels Krogsgaard-Larsen, Lennart Bunch, Darryl S. Pickering, Jed T. Syrenne, Markus Staudt, Piero Temperini, Younes Larsen, Birgitte Nielsen, Feng Yi, Aleksandra Moroz
Publikováno v:
ACS Chemical Neuroscience. 11:674-701
Competitive antagonists for ionotropic glutamate receptors (iGluRs) are highly valuable tool compounds for studying health and disease states in the central nervous system. However, only few subtype selective tool compounds are available and the disc
Autor:
Kasper B. Hansen, Mikkel Krell-Jørgensen, Eloi Astier, Younes Larsen, Birgitte Nielsen, Jed T. Syrenne, Christian B. M. Poulie, Anna Alcaide, Feng Yi, Darryl S. Pickering, Morten Storgaard, Walden E. Bjørn-Yoshimoto, Karla Frydenvang, Lennart Bunch, Anders A. Jensen
Publikováno v:
ACS Chem Neurosci
Development of pharmacological tools for the ionotropic glutamate receptors (iGluRs) is imperative for the study and understanding of the role and function of these receptors in the central nervous system. We report the synthesis of 18 analogues of (
Autor:
Silke, Kayser, Jacob C, Hansen, Markus, Staudt, Aleksandra, Moroz, Younes, Larsen, Piero, Temperini, Feng, Yi, Jed T, Syrenne, Niels, Krogsgaard-Larsen, Stylianos, Iliadis, Birgitte, Nielsen, Kasper B, Hansen, Darryl S, Pickering, Lennart, Bunch
Publikováno v:
ACS Chem Neurosci
Competitive antagonists for ionotropic glutamate receptors (iGluRs) are highly valuable tool compounds for studying health and disease states in the central nervous system. However, only few subtype selective tool compounds are available and the disc
Autor:
Seppo Auriola, Kasper B. Hansen, Mikko Gynther, Yevheniia Ishchenko, Darryl S. Pickering, Birgitte Nielsen, Aleksanteri Petsalo, Younes Larsen, Liwei Han, Jacob C. Hansen, Silke Kayser, Ilaria Proietti Silvestri, Tarja Malm, Lennart Bunch
Publikováno v:
Journal of Medicinal Chemistry. 60:9885-9904
The most common solid tumors show intrinsic multidrug resistance (MDR) or inevitably acquire suchwhen treated with anticancer drugs. In this work, we describe the discovery of a peripherally restricted, potent, competitive NMDA receptor antagonist 1l
Autor:
Rasmus P. Clausen, Jette S. Kastrup, Cristina Vara Navarrete, Birgitte Nielsen, Anders A. Jensen, Darryl S. Pickering, Karla Frydenvang, Shuang-Yan Wang, Ali Al-Musaed, Younes Larsen
Publikováno v:
Journal of medicinal chemistry. 59(5)
A series of analogues of the (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptor agonist BnTetAMPA (5b) were synthesized and characterized pharmacologically in radioligand binding assays at native and cloned AMPA receptors