Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Youn-Jae Kim"'
Publikováno v:
Cancers, Vol 15, Iss 23, p 5504 (2023)
Lung adenocarcinoma is a crucial contributor to cancer-related mortality; however, effective treatments remain challenging. The present study aimed to investigate the role of hemoglobin subunit theta 1 (HBQ1), an α subunit of hemoglobin whose expres
Externí odkaz:
https://doaj.org/article/8534990f36f442f191da0895fb523694
Publikováno v:
Cancers, Vol 14, Iss 1, p 19 (2021)
Lung adenocarcinoma is one of the leading causes of cancer-related deaths. Despite the availability of advanced anticancer drugs for lung cancer treatment, the prognosis of patients still remains poor. There is a need to explore novel oncogenic mecha
Externí odkaz:
https://doaj.org/article/aabba758597e46c18135b1d2eb54464f
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 3, Pp 1270-1283 (2018)
Background/Aims: Recent studies have revealed that many long non-coding RNAs (lncRNAs) play oncogenic or tumor-suppressive roles in various cancers. Lung cancer is the leading cause of cancer-related death worldwide, and many lung cancer patients fre
Externí odkaz:
https://doaj.org/article/e9bb528bc31b4603940adac4a87aecdd
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-11 (2017)
Abstract Background Most DNA cancer methylation markers are based on the transcriptional regulation of the promoter-gene relationship. Recently, the importance of long-range interactions between distal CpGs and target genes has been revealed. Here, w
Externí odkaz:
https://doaj.org/article/5fade54c47b1431a9a216504d8a08c5f
Autor:
Seong-Min Park, Eun-Young Choi, Mingyun Bae, Sunshin Kim, Jong Bae Park, Heon Yoo, Jung Kyoon Choi, Youn-Jae Kim, Seung-Hoon Lee, In-Hoo Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migratio
Externí odkaz:
https://doaj.org/article/07788f10331948db8924a111c4c9b877
Autor:
Kang Seon Lee, Paramita Chatterjee, Eun-Young Choi, Min Kyung Sung, Jaeho Oh, Hyejung Won, Seong-Min Park, Youn-Jae Kim, Soojin V Yi, Jung Kyoon Choi
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007311 (2018)
Adrenergic α2C receptor (ADRA2C) is an inhibitory modulator of the sympathetic nervous system. Knockout mice for this gene show physiological and behavioural alterations that are associated with the fight-or-flight response. There is evidence of pos
Externí odkaz:
https://doaj.org/article/f487f9f7838046198014b087839f2085
Autor:
Ryuk-Jun Kwon, Myoung-Eun Han, Youn-Jae Kim, Yun Hak Kim, Ji-young Kim, Liangwen Liu, Woong Heo, Sae-Ock Oh
Publikováno v:
Tumor Biology, Vol 39 (2017)
Zinc-fingers and homeoboxes 1 (ZHX1) is a nuclear transcription repressor and known to be involved in cell differentiation and tumorigenesis. However, the pathophysiological roles of ZHX1 have not been characterized in glioblastoma. We examined ZHX1
Externí odkaz:
https://doaj.org/article/b8809d9bda1942cda6d75552a9596208
Autor:
Jinlong Yin, Gunwoo Park, Tae Hoon Kim, Jun Hee Hong, Youn-Jae Kim, Xiong Jin, Sangjo Kang, Ji-Eun Jung, Jeong-Yub Kim, Hyeongsun Yun, Jeong Eun Lee, Minkyung Kim, Junho Chung, Hyunggee Kim, Ichiro Nakano, Ho-Shin Gwak, Heon Yoo, Byong Chul Yoo, Jong Heon Kim, Eun-Mi Hur, Jeongwu Lee, Seung-Hoon Lee, Myung-Jin Park, Jong Bae Park
Publikováno v:
PLoS Biology, Vol 14, Iss 1, p e1002367 (2016)
[This corrects the article DOI: 10.1371/journal.pbio.1002152.].
Externí odkaz:
https://doaj.org/article/5d8e6f20832a479fa656349dbb071f2d
Autor:
Jinlong Yin, Gunwoo Park, Tae Hoon Kim, Jun Hee Hong, Youn-Jae Kim, Xiong Jin, Sangjo Kang, Ji-Eun Jung, Jeong-Yub Kim, Hyeongsun Yun, Jeong Eun Lee, Minkyung Kim, Junho Chung, Hyunggee Kim, Ichiro Nakano, Ho-Shin Gwak, Heon Yoo, Byong Chul Yoo, Jong Heon Kim, Eun-Mi Hur, Jeongwu Lee, Seung-Hoon Lee, Myung-Jin Park, Jong Bae Park
Publikováno v:
PLoS Biology, Vol 13, Iss 5, p e1002152 (2015)
Epidermal growth factor receptor variant III (EGFRvIII) has been associated with glioma stemness, but the direct molecular mechanism linking the two is largely unknown. Here, we show that EGFRvIII induces the expression and secretion of pigment epith
Externí odkaz:
https://doaj.org/article/9adb21b0e48747189b062bec6fafa021
Autor:
Mi Ra Kim, Ji Hye Jang, Chang Sik Park, Taek-Keun Kim, Youn-Jae Kim, Junho Chung, Hyunbo Shim, In Hyun Nam, Jung Min Han, Sukmook Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 3, p 566 (2017)
Vascular cell adhesion molecule-1 (VCAM-1) is closely associated with tumor progression and metastasis. However, the relevance and role of VCAM-1 in lung cancer have not been clearly elucidated. In this study, we found that VCAM-1 was highly overexpr
Externí odkaz:
https://doaj.org/article/086780e07e3d40b98bd539cce9c139c2