Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Youn-Jae Kim"'
Publikováno v:
Cells, Vol 13, Iss 19, p 1659 (2024)
Autophagy is essential for cell survival and cellular homeostasis under various stress conditions. Therefore, autophagy dysfunction is associated with the pathogenesis of various human diseases. We explored the regulatory role of RhoBTB3 in autophagy
Externí odkaz:
https://doaj.org/article/9a87846afdf74f7ca8cddcfff17cb0b9
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 3, Pp 1270-1283 (2018)
Background/Aims: Recent studies have revealed that many long non-coding RNAs (lncRNAs) play oncogenic or tumor-suppressive roles in various cancers. Lung cancer is the leading cause of cancer-related death worldwide, and many lung cancer patients fre
Externí odkaz:
https://doaj.org/article/e9bb528bc31b4603940adac4a87aecdd
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-11 (2017)
Abstract Background Most DNA cancer methylation markers are based on the transcriptional regulation of the promoter-gene relationship. Recently, the importance of long-range interactions between distal CpGs and target genes has been revealed. Here, w
Externí odkaz:
https://doaj.org/article/5fade54c47b1431a9a216504d8a08c5f
Autor:
Seong-Min Park, Eun-Young Choi, Mingyun Bae, Sunshin Kim, Jong Bae Park, Heon Yoo, Jung Kyoon Choi, Youn-Jae Kim, Seung-Hoon Lee, In-Hoo Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Histone variants act as transcriptional activators and repressors and have been linked to cancer progression. Park and Choi et al. show that the histone H3.3 overexpression is associated with early-stage lung cancer, and promotes cancer cell migratio
Externí odkaz:
https://doaj.org/article/07788f10331948db8924a111c4c9b877
Autor:
Kang Seon Lee, Paramita Chatterjee, Eun-Young Choi, Min Kyung Sung, Jaeho Oh, Hyejung Won, Seong-Min Park, Youn-Jae Kim, Soojin V Yi, Jung Kyoon Choi
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007311 (2018)
Adrenergic α2C receptor (ADRA2C) is an inhibitory modulator of the sympathetic nervous system. Knockout mice for this gene show physiological and behavioural alterations that are associated with the fight-or-flight response. There is evidence of pos
Externí odkaz:
https://doaj.org/article/f487f9f7838046198014b087839f2085
Autor:
Ryuk-Jun Kwon, Myoung-Eun Han, Youn-Jae Kim, Yun Hak Kim, Ji-young Kim, Liangwen Liu, Woong Heo, Sae-Ock Oh
Publikováno v:
Tumor Biology, Vol 39 (2017)
Zinc-fingers and homeoboxes 1 (ZHX1) is a nuclear transcription repressor and known to be involved in cell differentiation and tumorigenesis. However, the pathophysiological roles of ZHX1 have not been characterized in glioblastoma. We examined ZHX1
Externí odkaz:
https://doaj.org/article/b8809d9bda1942cda6d75552a9596208
Autor:
Jinlong Yin, Gunwoo Park, Tae Hoon Kim, Jun Hee Hong, Youn-Jae Kim, Xiong Jin, Sangjo Kang, Ji-Eun Jung, Jeong-Yub Kim, Hyeongsun Yun, Jeong Eun Lee, Minkyung Kim, Junho Chung, Hyunggee Kim, Ichiro Nakano, Ho-Shin Gwak, Heon Yoo, Byong Chul Yoo, Jong Heon Kim, Eun-Mi Hur, Jeongwu Lee, Seung-Hoon Lee, Myung-Jin Park, Jong Bae Park
Publikováno v:
PLoS Biology, Vol 14, Iss 1, p e1002367 (2016)
[This corrects the article DOI: 10.1371/journal.pbio.1002152.].
Externí odkaz:
https://doaj.org/article/5d8e6f20832a479fa656349dbb071f2d
Autor:
Jinlong Yin, Gunwoo Park, Tae Hoon Kim, Jun Hee Hong, Youn-Jae Kim, Xiong Jin, Sangjo Kang, Ji-Eun Jung, Jeong-Yub Kim, Hyeongsun Yun, Jeong Eun Lee, Minkyung Kim, Junho Chung, Hyunggee Kim, Ichiro Nakano, Ho-Shin Gwak, Heon Yoo, Byong Chul Yoo, Jong Heon Kim, Eun-Mi Hur, Jeongwu Lee, Seung-Hoon Lee, Myung-Jin Park, Jong Bae Park
Publikováno v:
PLoS Biology, Vol 13, Iss 5, p e1002152 (2015)
Epidermal growth factor receptor variant III (EGFRvIII) has been associated with glioma stemness, but the direct molecular mechanism linking the two is largely unknown. Here, we show that EGFRvIII induces the expression and secretion of pigment epith
Externí odkaz:
https://doaj.org/article/9adb21b0e48747189b062bec6fafa021
Autor:
Ho-Shin Gwak, Tae Hoon Kim, Guk Heui Jo, Youn-Jae Kim, Hee-Jin Kwak, Jong Heon Kim, Jinlong Yin, Heon Yoo, Seung Hoon Lee, Jong Bae Park
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47449 (2012)
Radiation is a core part of therapy for malignant glioma and is often provided following debulking surgery. However, resistance to radiation occurs in most patients, and the underlying molecular mechanisms of radio-resistance are not fully understood
Externí odkaz:
https://doaj.org/article/942776d712534561abb7484e1d009299
Autor:
Youn-Jae Kim, Se-Jeong Park, Eun Young Choi, Sol Kim, Hee Jin Kwak, Byong Chul Yoo, Heon Yoo, Seung-Hoon Lee, Daesoo Kim, Jong Bae Park, Jong Heon Kim
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28308 (2011)
Aberrant miR-21 expression is closely associated with cell proliferation, anti-apoptosis, migration, invasion, and metastasis in various cancers. However, the regulatory mechanism of miR-21 biogenesis is largely unknown. Here, we demonstrated that th
Externí odkaz:
https://doaj.org/article/b07661ae72c746febce3bd435792b877