Deimmunization of flagellin for repeated administration as a vaccine adjuvant

Autor: Koemchhoy Khim, Yong Jun Bang, Sao Puth, Yoonjoo Choi, Youn Suhk Lee, Kwangjoon Jeong, Shee Eun Lee, Joon Haeng Rhee

Publikováno v: npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)

Abstract Flagellin, a protein-based Toll-like receptor agonist, is a versatile adjuvant applicable to wide spectrum of vaccines and immunotherapies. Given reiterated treatments of immunogenic biopharmaceuticals should lead to antibody responses precl

Externí odkaz: https://doaj.org/article/a8f24b6ddcc2499695bfd6ace50b7b97

Deimmunization of flagellin for repeated administration as a vaccine adjuvant

Autor: Joon Haeng Rhee, Yoonjoo Choi, Youn Suhk Lee, Shee Eun Lee, Koemchhoy Khim, Sao Puth, Yong Jun Bang, Kwangjoon Jeong

Publikováno v: NPJ Vaccines
npj Vaccines, Vol 6, Iss 1, Pp 1-14 (2021)

Flagellin, a protein-based Toll-like receptor agonist, is a versatile adjuvant applicable to wide spectrum of vaccines and immunotherapies. Given reiterated treatments of immunogenic biopharmaceuticals should lead to antibody responses precluding rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c68a2b9b0a842554e20a9ab99c244cb
http://europepmc.org/articles/PMC8438039

A built-in adjuvant-engineered mucosal vaccine against dysbiotic periodontal diseases

Autor: Je-Hwang Ryu, Jeong Tae Koh, In-Chol Kang, Hye Hwa Lee, Seol Hee Hong, Youn Suhk Lee, Sug-Joon Ahn, Wenzhi Tan, Soo Young Kim, Sao Puth, Hye Suk Hwang, Shee Eun Lee, Joong-Ki Kook, Sethupathy Sivasamy, Hee Sam Na, Kwangjoon Jeong, Joon Haeng Rhee

Publikováno v: Mucosal immunology. 12(2)

Periodontitis is associated with a dysbiotic shift in the oral microbiome. Vaccine approaches to prevent microbial shifts from healthy to diseased state in oral biofilms would provide a fundamental therapeutic strategy against periodontitis. Since de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a26ab67bf8358cf5f63094f64e238e
https://pubmed.ncbi.nlm.nih.gov/30487648

Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer

Autor: Vivek Verma, Young Chul Sung, Saji Uthaman, Seol Hee Hong, Shee Eun Lee, Joon Haeng Rhee, Kwangjoon Jeong, Youn Suhk Lee, In-Kyu Park, Jaetae Lee, Jung-Joon Min, Tra-My Nu Duong

Publikováno v: Oncoimmunology

Cervical cancer is a high-incidence female cancer most commonly caused by human papilloma virus (HPV) infection of the genital mucosa. Immunotherapy targeting HPV-derived tumor antigens (TAs) has been widely studied in animal models and in patients.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cffd44a05239ca132b078b7a045aec3
https://doi.org/10.1080/2162402x.2015.1081328

Acid-base, nephrolithiasis and divalent ions

Autor: William Noonan, Maria Svelto, Pier Paolo Sainaghi, Shirley J. Dopson, Yoon Chul Jung, Yipu Chen, Antonia Fabris, Sofia Trompouki, Daria Vachugova, Giovanni Gambaro, P. Richard Grimm, Gonzalo Martinez, Promsuk Jutabha, Gabriella Porcellini, Hyo-Young Kim, Renzo Bonofiglio, Lucia Andrade, Po-Jen Hsiao, Galina Baturina, Bettina Krueger, Alejandro Joyas, Andrey Sorokin, Zoran Cukic, Ho-Jung Kim, Arthur John, Søren Nielsen, Jay Wook Lee, María Márquez, Juan Carlos Q. Velez, Sunena Srivastava, Silvana Rvaglio, Chun Ji Jin, Mutsuko Ohnishi, Tewoldemedhn Yabarek, Jin Suk Han, Rosita Greco, Talita Rojas Sanches, Kristin Brooks, Sang-Woong Han, Essam Khidr, Chiara Lanzani, Ji Yong Jung, Silke Haerteis, Donald T. Ward, Zoran Kovacevic, Afshin Azhir, Alejandra Carrasco, Hsin-Chi Wu, Magdy ElSharkawy, Luís Coentrão, Zenaide P. Moyses, Roberto Jalil, Keiko Uchida, Debra L. Irsik, Erling B. Pedersen, Robert J. Unwin, Eliete Caló Romero, Maja T. Lindenmeyer, Lubov Katkova, Jiro Kumagai, Toru Kimura, Hernán Borja, Clemens D. Cohen, M. Rita Lecca, Marta Nowik, Dimitrios Hadjiyannakos, Mathieu Lemaire, Shinichi Uchida, Teruyo Nakatani, Hiroyuki Sakurai, Kwon Wook Joo, Jesper N. Bech, Ji Y. Lee, William G. Robertson, Rudolf P. Wüthrich, Manuel Pestana, Jorge Vega, Tatemitsu Rai, Yun Kyu Oh, Xiao Li, Francisco Manriquez, Grazia Tamma, Bolesław Rutkowski, Alexandra C. Rankin, Alexander Staruschenko, Tomomi Nemoto, Neelanjana Dutt, Nan Chen, Francesca Romano, Evgeniy Solenov, Domenica Lasorsa, R. Bansal, Jürgen Cox, Marcelo Bastos, André W. Brändli, Roberta Morozetti, Giuseppe Procino, Tae-Hwan Kwon, Olivier Devuyst, Jørn Starklint, Jeong-Eun Lee, Nicola Marchionna, Yuen Fei Wong, Fatemeh Nasseri, Teresa Papalia, Min Jeong Son, Jeremy Field, Carolina Cannillo Graffe, Fernando Assuno, Nicolò Borsa, J. Ruth Wu-Wong, Youn Suhk Lee, Gilda Stringini, J.S. Sandhu, Chang B. Lee, Margaret Ross-Styles, Medhat Ali, V. Midha, Ellappan Babu, Giovanna Valenti, Dragan Savic, Vasilis Filiopoulos, Akihito Ohta, Eriko Ohta, Viatcheslav Nesterov, Helmuth Goecke, Beate Lanske, Aleksandr Ilyaskin, Julio Salinas, Olivia Beloto-Silva, Marco Materassi, Ki Young Na, Jeffrey B. Kopp, Tomohiro Itoh, M. Shawkat Razzaque, Sekineh Shahsavari, Ana Carolina de Bragança, Bruce A. Cooper, Carolina Alejandra Ilabaca Diaz, Tadic Jelena, Bruce M. Hendry, Jin S. Lim, Hye Jung Cho, Joo-Hark Yi, Weiming Wang, Masashi Suzuki, Jean-Daniel Horisberger, Carla Cristiane da Motta Bernardo, Giuseppe Bianchi, Francesco Emma, Antonio Carlos Seguro, Marie Louise Syrén, M. Mann, Dimosthenis Vlassopoulos, Ettore Bartoli, Wen Zhang, Catherine Roberts, Rebecca Winzeler, Georgiy Khodus, Hitoshi Endou, Wojciech Wołyniec, Alexei Diakov, Monica Carmosino, Luca Bergamasco, Patrice Ambuehl, Obrencevic Katarina, Qihe Xu, Alireza Merikhi, Shih-Hua Lin, María José Cubillas Rodríguez, Ioannis Koutis, Hao Shi, Oleh Pochynyuk, Ana Velic, Daniel Moura, Jos Augusto Meneses, Steven C. Sansom, Patricia Wahl, Maria Oliveira-Souza, Tengis S. Pavlov, Jiahui Wang, Paolo Manunta, Masaki Nakane, Yanyan Wang, Peter J. Scambler, Takashi Taguchi, Boris Macek, Casagranda Ivo, Mayuko Kawashima, Elena Vitale, Toshiro Fujita, Fernando Lucas, Ahmed Abd-Elaazeem, Liliana Gadola, Katia R. Cesar, Malcolm Maden, Limin Yang, M. Kaur, Alexandre Braga Libório, Lisa Mastrofrancesco, Fernando Rojas, Nam Ju Heo, Antonio J. Magaldi, Elena Puricelli, Shoko Horita, Jung-Suk Lim, Luigi Castello, Hideomi Yamada, Marcus Krüger, Silvana Tedeschi, Ling Qin, Anna Masiak, Hong Ren, Claudia Barbieri, Nilufar Mohebbi, Christoph Korbmacher, Kenichi Ishibashi, U.-Seok Noh, Naohiko Anzai, Thomas G. Lauridsen, Yu-Jung Lee, Heidi Fodstad, Vjatzeslav Nesterov, Alberto Bettinelli, Wanda D McCormick, Mara Steffanini, Antonio Lupo, Saban Elitok, Leonella Luzardo, Carsten A. Wagner, Alf Corsenca, Hans-Peter Gaeggeler, Pingyan Shen, Osamu Yamazaki, George Seki, Henrik Vase, Pauling Chu, Kyu Youn Ahn, Shigeru Ko, Dimitrios Lazarou, Moon-Chang Baek, Ahmed Chahdi, Tracy Delay, Sei Sasaki, Anke Dahlmann

Publikováno v: NDT Plus. 2:ii756-ii756

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55a68fa7c3158d2f257a2d157b9cb6b6
https://doi.org/10.1093/ndtplus/2.s2.2