Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Youling Wu"'
Autor:
Yichen Wang, Xuyao Zhang, Jiajun Fan, Wei Chen, Jingyun Luan, Yanyang Nan, Shaofei Wang, Qicheng Chen, Yujie Zhang, Youling Wu, Dianwen Ju
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundAntibody drug conjugate (ADC) showed potent therapeutic efficacy in several types of cancers. The role of autophagy in antitumor effects of ADC remains unclear.MethodsIn this study, the ADC, Rituximab-monomethyl auristatin E (MMAE) with a V
Externí odkaz:
https://doaj.org/article/a2ac534923784c0cbed630e44b19bf93
Autor:
Jingyun Luan, Yichen Wang, Xuyao Zhang, Youling Wu, Yujie Zhang, Wei Chen, Jiajun Fan, Qicheng Chen, Dianwen Ju, Shaofei Wang, Yanyang Nan
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Background Antibody drug conjugate (ADC) showed potent therapeutic efficacy in several types of cancers. The role of autophagy in antitumor effects of ADC remains unclear. Methods In this study, the ADC, Rituximab-monomethyl auristatin E (MMAE) with
Publikováno v:
Pharmaceutical Bioprocessing. 3:285-292
Intense efforts in bioprocessing development have been made to improve the production of Chinese Hamster Ovary-based biopharmaceuticals. However, lacking an efficient host cell has hampered therapeutic protein production. This article reviews means b
Autor:
Qiping Zhao, Liujia Li, Bing Huang, Hongyu Han, Youling Wu, Shunhai Zhu, Hui Dong, Yange Wang
Publikováno v:
Parasitology Research. 113:2915-2923
Lactate dehydrogenase (LDH) is a key enzyme in the glycolytic pathway and is crucial for parasite survival. In this study, we cloned and expressed the LDH of Eimeria tenella (EtLDH). Real-time polymerase chain reaction and Western blot analysis revea
Autor:
Qiping Zhao, Di Wu, Youling Wu, Hongyu Han, Enle Pei, Hui Dong, Bing Huang, Yange Wang, Liujia Li, Shunhai Zhu
Publikováno v:
Acta Parasitologica. 60
Hepatozoon species are the most common hemoparasites of snakes. In this study, Hepatozoon parasites were examined for the first time in king rat snakes (Elaphe carinata) from Shanghai, China. All 10 snakes were found to be infected with Hepatozoon ga
Autor:
Qiping Zhao, Ting Li, Liujia Li, Shunhai Zhu, Bing Huang, Hongyu Han, Youling Wu, Yange Wang, Hui Dong
Publikováno v:
Parasitology research. 113(2)
The precocious lines of Eimeria spp. have unique phenotypes. However, the genetic basis of the precocious phenotype is still poorly understood. The identification of Eimeria genes controlling the precocious phenotype is of immense importance in the f
Publikováno v:
Biopolymers. 34:403-414
Urethane bonds, derived from the hydroxyl group of the tyrosine side chain, have been investigated as a new type of amide bond mimetic in the design of pseudopeptides. The structure of a representative cyclic pseudotetrapeptide that consists of an -A
Publikováno v:
Synthetic Communications. 23:3055-3060
Fmoc-Argw, w′(Boc)2-OH and Boc-Argw, w′(Cbz)2-OH were prepared in two steps: Guanylation of Cu(II)-ornithine complex at Nδ with N, N′bis-urethane protected derivatives of 1-guanylpyrazole, followed by Nα-protection using either 9-fluorenylmet
Publikováno v:
ChemInform. 25
Publikováno v:
Analytical biochemistry. 270(2)
Proteins that are heavily glycosylated pose unique challenges in their biophysical characterization. In particular, molecular weight analysis is exacerbated by such glycosylation. For example, glyoproteins are refractory to careful mass spectrum anal